Diuretics Overview

Flashcards based on diuretics, their types, mechanisms, uses, and side effects.

What is the mechanism of action (MOA) of diuretics?

Diuretics promote urine output by inhibiting sodium reabsorption at different parts of the renal tubular system.

Which diuretic is a thiazide with a long half-life?

Chlortalidone.

What is the mechanism of action (MOA) of diuretics?

Diuretics promote urine output by inhibiting sodium reabsorption at different parts of the renal tubular system.

Which diuretic is a thiazide with a long half-life?

Chlortalidone.

What are the potassium-sparing diuretics mentioned?

Amiloride and Triamterene.

What is the use of Spironolactone?

Used in cases of liver failure and ascites as an aldosterone antagonist.

What type of diuretic is Mannitol?

Osmotic diuretic, used in cerebral edema.

What is the function of carbonic anhydrase inhibitors in diuretics?

They are used in glaucoma treatment.

What are common side effects of loop diuretics?

Ototoxicity, acute urinary retention, hyperglycemia, hyperuricemia, hypokalemia.

What does the loop diuretic inhibit in the kidney?

It stops the Na+/K+/Cl- cotransporter in the ascending limb of the loop of Henle.

What is the typical onset and duration of action for loop diuretics?

Onset is 1 hour, and duration is 6 hours.