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What are the functions of iron
part of heme and cofactor for enzymes
What animals receive iron injections at birth
pigs
Sources of iron
feeds, meat
What is a poor source of iron
milk
The human adult contains how much iron
3g
How much of the human iron content is in hemoglobin
2g
RBCs last how long before iron is recycled
120 days
Some iron is stored in the
liver and spleen
the iron storage protein is
ferritin
Anemia is a shortage of
hemoglobin
Anemia can be caused by
iron deficiency (most common deficiency)
How to reduce Fe deficiency in humans
-control parasites and malaria
-eat more vit C
-eat more meat
-check levels of Ca/phenolics
-add Fe to table salt
T/F: iron is excreted in large ammounts
false, almost no iron is secreted
Excess iron can come from
-cooking acid foods in iron pots
-eating iron pills
(can cause shock, death, intestinal bleeding, toxicity from free radicals)
Iron is found in many foods (beets and spinach) but is not always
available
The functions of copper
-many enzymes, especially oxidases
-formation of bone, collagen, elastin, hemoglobin
Copper is found in
most feeds
A deficiency of copper can cause
• Wasting
• Anemia
• Swayback (ataxia) in lambs and calves
• Bone defects
• Bursting of blood vessels
• Depigmentation (inactive tyrosinase), "spectacles" around eyes
• "Steely wool"
Who has a high copper requirements
sheep, lambs for wool. Deficiency gives steely wool
A deficiency of copper is rare in
humans
induced copper deficiencies can arise from
excess Zn or Mo (galvanized metal found in feeders or drinkers)
How does excess zinc cause copper deficiency?
When there's too much zinc in thebody, the body produces moremetallothionein, a binding proteinthat helps absorb copper.
What animal is easily poisoned by excess copper
sheep
What animal can handle high Cu levels
pigs
With excess copper, sheep can get
jaundice (don't feed them cow feed, cows can handle more)
Excess copper for provide certain benefits to pigs, like
acting as a growth stimulant
Excess copper isn't advised for pigs because
it might not be good for human consumption, and have mineral leeching in manure, soil, and water
what is one function of zinc
for enzymes
Sources of zinc
meats (poultry and fish)
Signs of zinc deficiency
• Dermatitis
• Poor wound healing
• Signs often vague
What other supplements may cause zinc deficiencies
High Ca intake or Fe supplements may cause it
What can reduce zinc availability
phytate
Sometime iron, phosphorous and zinc are in a plant but not available, because they are bound to
phytate
Excess in zinc can come from
metal working (causing brassfounder's ague, where brass is Zn and Cu)
What two minerals can be growth promoters in pigs
Cu
Zn
Manganese function
enzymes
Manganese sources
most feeds
T/F: corn is high in manganese
false, it is low
Deficiency of manganese causes
• Poor cartilage and bone
• Slipped tendon in chickens
What mineral can cause Mn deficiency
High Ca can cause
Mn is toxic on
inhalation (easy to have excess in mines)
There is little storage of
Mn
Selenium functions
enzymes protecting from oxidative damage (Glutathione peroxidase, superoxide dismutase)
part of proteins (selenomethionine or selenocysteine)
Some forages can accumulate
selenium
Selenium can be added to soil via
fertilizers
What soil are low in Se
-east side of NA
-South island of NZ
Selenium deficiency effects
-oxidative damage (white muscle and dystrophy lambs and calves)
-Liver necrosis
-low disease resistance
-poor feathering
-retained placentas in cattle
The safety margin for selenium is __________
narrow, toxicity level is low
Plants can become toxic sources of Se since they
accumulate Se
excess Se effects
hair and hoof loss
Selenium overlaps with what vitamin
Vitamin E
What is one function of Molybdenum (MO)
enzymes
T/F: Normal diets have adequate MO sources
true
T/F: Deficiencies of MO are common
false, unknown so far. Only one case
Excess of MO is ________
rare
An excess in MO causes a deficiency in
a Cu deficiency
How does an excess in MO cause a Cu deficiency
•High Mo = Cu thiomolybdate
•Mo and Sulfur interact in the digestive tract of ruminants and form thiomolybdate. If Mo is in excess then thiomolybdates can interfere with Cu absorption
MO can be added to soils in order to
increase nodulation in legumes to increase N fixation
Legumes work with ________________ bacteria to form nodules that fix nitrogen
rhizobium
Function of cobalt
part of B12
Sources of Co
mineral supplements
rumen boluses
feed grown on Co-adequate soil
Deficiency of Co effects
• Deficiency:
• Loss of appetite
• Anemia
• Wasting
• Death
Rumen bacteria convert _____ to ___________ (think vitamins)
Co
Vit B12
T/F: Horses are more resistant to B12 deficiency than cows
True
Iodine functions as part of
part of thyroid hormone, thyroxin
Thyroxin influences
embryonic development and metabolic rate
Sources of iodine
iodized salt, milk and fish, feed gown on I-adequate soils
Being close to the ocean means
you are less likely to be iodine deficient
Iodine deficiency effects
• Deformity
• Impaired mental development
• May be born dead, lack of hair
• Goiter (enlargement of thyroid, swollen neck) (fairly common still)
Iodine deficiency is more common in
inland regions
Induced deficiency of iodine can arise from
-plants that contain goitrogens (antithyroid compounds)
What plant families are known to have goitrogens
brassica and cassava
Excess of iodine can cause
-goiter
-thyroid inflammation
-hyperthyroidism
Excess of iodine can arise from eating too much
seaweed
Fluorine function
-bones and teeth (have trace F)
Fluoride sources
water
Deficiency of fluorine can cause
tooth decay, weak bones, worsening osteoporosis
Excess fluorine can cause
-poor growth
-tissue damage
-marks on teeth
-weaken teeth
-exostoses (lumps on bones)
Boron is required by
plants and green algae, and some bacteria
Boron may be associated with growth in
pigs
Chromium functions
-glucose absorption (help insulin)
-immune responses
-leaner carcasses
Excess of chromium (Cr) can cause
-hypoglycemia
-stomach issues
-organ damage
Silicon (Si) function
-structural material for diatoms and grasses
-involved in animal tissues (CT, bone, eggshells)
_________________is said to have some anti-cancer action
germanium (GE)
____________ sometimes used medically to increase bone density
strontium (Sr)
Other minerals include
Tungsten (W)
Strontium (Sr)
Nickel (Ni)
Vanadium (V)
Germanium (Ge)