Polar or Hydrophilic Amino Acids

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Last updated 3:22 AM on 5/27/26

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Serine (Ser, S)

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Threonine (Thr, T)

3

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Cysteine (Cys, C)

4

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Asparagine (Asn, N)

5

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Glutamine (Gln, Q)

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Histidine (His, H) pKa = 6.0

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Aspartic Acid (Asp, D) pKa = 3.9

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Glutamic Acid (Glu, E) pKa = 4.1

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Lysine (Lys, K) pKa = 10.8

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Arginine (Arg, R) pKa = 12.5