Tablet Compression Process

Compression

The stage in tablet manufacturing where granules are formed into tablets using a tablet press.

Line Clearance

A verification process ensuring that equipment and production areas are clean and clear of previous product residues and ready for the next batch.

Batch Manufacturing Record (BMR)

An approved document detailing the manufacturing history of a specific batch of products.

D-Tooling

The specific tooling components used in tablet compression, including punches and dies.

Intermediate Bulk Container (IBC)

A large container used to transfer and store bulk materials, such as lubricated granules in tablet manufacturing.

Fill Cam

A component that controls the amount of powder filled into the die cavities during tablet compression.

Pre-compression

The initial compression phase where air is expelled from the powder bed before main compression.

Critical Process Parameters (CPPs)

Key parameters that are monitored to ensure the quality and consistency of the tablet manufacturing process.

In-Process Controls (IPC)

Procedures conducted during tablet production to monitor critical attributes such as weight and hardness.

Material Reconciliation

A post-process analysis comparing the theoretical yield of tablets to the actual output to assess efficiency and loss.

Tablet Deduster

A device used to remove excess powder and dust from tablets after they are ejected from the tablet press.

Compression Force

The force applied by the upper and lower punches during the main compression phase to form tablets.

Compression Stability

The ability of the compression process to maintain consistent output and quality of tablets during production.

Tablet Ejection

The process of removing tablets from the die after they have been formed in the tablet press.

Quality Control Parameters

Attributes such as tablet diameter, thickness, hardness, and disintegration time that are measured to ensure tablet quality.

Safety Guards

Protective components of the tablet press that ensure operator safety during the manufacturing process.

Feed Frame

The component of the tablet press that distributes granules from the hopper into the die cavities.

Tablet Coating

The process that tablets undergo after compression to improve stability, appearance, or release characteristics.

Dust Extraction System

A system used to remove airborne particles and dust generated during the manufacturing process, ensuring a clean environment.