Drug(s) with the following indications: acute pulmonary edema
Furosemide
60
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Drug(s) with the following indications: primary hyperaldosteronism
Spironolactone
61
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Drug(s) with the following indications: angina
Amlodipine, Nifedipine, Diltiazem, Verapamil
62
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Drug(s) with the following indications: arrhythmia (rate control)
Diltiazem, Verapamil
63
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Simplified MOA for Hydrochlorothiazide (HCTZ)
inhibits sodium reabsorption in the distal tubule causing increased excretion of sodium and hydrogen ions
64
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Simplified MOA for Chlorthalidone
inhibits sodium reabsorption in the distal tubule causing increased excretion of sodium and hydrogen ions
65
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Simplified MOA for Triamterene/hydrochlorothiazide
blocks epithelial sodium channels which inhibits sodium reabsorption, decreases the function of Na+/K+ ATPase, causing potassium retention and decreased Ca, Mg, and H excretion/ inhibits sodium reabsorption in the distal tubule causing increased excretion of sodium and hydrogen ions
66
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Simplified MOA for Furosemide
inhibits sodium and chloride reabsorption in the loop of Henle and interferes with chloride-binding cotransport system
67
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Simplified MOA for Spironolactone
competes with aldosterone in distal convoluted renal tubule which increases sodium chloride and water excretion while conserving potassium and hydrogen ions
68
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Simplified MOA for Amlodipine
calcium channel blocker that inhibits the influx of calcium across cell membranes in vascular smooth muscle causing vasodilation
69
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Simplified MOA for Nifedipine
calcium channel blocker that inhibits the influx of calcium across cell membranes in vascular smooth muscle causing vasodilation
70
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Simplified MOA for Diltiazem
calcium channel blocker that inhibits the influx of calcium across cell membranes in vascular smooth muscle causing slowing of the SA and AV node conduction
71
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Simplified MOA for Verapamil
calcium channel blocker that inhibits the influx of calcium across cell membranes in vascular smooth muscle causing slowing of the SA and AV node conduction
72
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Simplified MOA for Amlodipine/benazepril
calcium channel blocker that inhibits the influx of calcium across cell membranes in vascular smooth muscle causing vasodilation/inhibits angiotensin-converting enzyme thus preventing conversion of angiotensin I to angiotensin II, ultimately reducing aldosterone secretion and increasing plasma renin activity
73
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Drug(s) with the following simplified MOA: inhibits sodium reabsorption in the distal tubule causing increased excretion of sodium and hydrogen ions
Hydrochlorothiazide (HCTZ), Chlorthalidone
74
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Drug(s) with the following simplified MOA: blocks epithelial sodium channels which inhibits sodium reabsorption, decreases the function of Na+/K+ ATPase, causing potassium retention and decreased Ca, Mg, and H excretion/ inhibits sodium reabsorption in the distal tubule causing increased excretion of sodium and hydrogen ions
Triamterene/hydrochlorothiazide
75
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Drug(s) with the following simplified MOA: inhibits sodium and chloride reabsorption in the loop of Henle and interferes with chloride-binding cotransport system
Furosemide
76
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Drug(s) with the following simplified MOA: competes with aldosterone in distal convoluted renal tubule which increases sodium chloride and water excretion while conserving potassium and hydrogen ions
Spironolactone
77
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Drug(s) with the following simplified MOA: calcium channel blocker that inhibits the influx of calcium across cell membranes in vascular smooth muscle causing vasodilation
Amlodipine, Nifedipine
78
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Drug(s) with the following simplified MOA: calcium channel blocker that inhibits the influx of calcium across cell membranes in vascular smooth muscle causing slowing of the SA and AV node conduction
Diltiazem, Verapamil
79
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Drug(s) with the following simplified MOA: calcium channel blocker that inhibits the influx of calcium across cell membranes in vascular smooth muscle causing vasodilation/inhibits angiotensin-converting enzyme thus preventing conversion of angiotensin I to angiotensin II, ultimately reducing aldosterone secretion and increasing plasma renin activity
Amlodipine/benazepril
80
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Simplified ADR list for Hydrochlorothiazide (HCTZ)