Pharmacy Practice Top 200 Spring Quarter 3rd Group

Mirabegron brand name

Myrbetriq

Mirabegron drug class

Beta-3 agonist

Mirabegron Indication

Overactive Bladder, Neurogenic detrusor overactivity

Mirabegron contraindication

Hypersensitivity

Mirabegron Box Warnings

None

Methotrexate brand name

Trexall

MEthotrexate drug class

immunosuppressant; antimetabolite

Methotrexate indication

non-hodgkin lymphoma, psoriasis, rheumatoid arthritis, juvenile rheumatoid arthritis

Methotrexate contraindication

Hypersensitivity, pregnancy, breastfeeding, alcohol use disorder, chronic liver disease, preexisting blood dyscrasias in patients treated for psoriasis and rheumatoid arthritis

Methotrexate box warnings

Bone marrow suppression, renal impairment, hepatotoxicity, GI toxicity, dermatologic toxicity, secondary malignancy, opportunistic infections, tumor lysis syndrome, radiotherapy, hypersensitivity, pregnancy

Mirabegron Briggs

Limited human data - animal data suggest low risk

Methotrexate briggs

contraindicated

Hydroxychloroquine brand name

Plaquenil

Hydroxychloroquine drug class

immunosuppressant; aminoquinoline

hydroxychloroquine indication

lupus erythematosus, malaria, rheumatoid arthritis

Hydroxychloroquine contraindication

Hypersensitivity, retinal or visual field changes from prior hydroxychloroquine, long-term use in children

Hydroxychloroquine box warnings

None

Hydroxychloroquine Briggs

Limited human data - probably compatible

Timolol brand name

Betimol, Timoptic

Timolol drug class

Beta-blocker, antiglaucoma agent

Timolol indication

Glaucoma

Timolol Contraindication

Hypersensitivity, asthma, COPD, sinus bradycardia, heart failure, cardiogenic shock

Timolol box warnings

None

Timolol Briggs

Human data suggest risk in 2nd and 3rd trimesters

Brimonidine brand name

Alphagan P, Lumify

Brominidine indication

Ocular hypertension, open-angle glaucoma, ocular redness

Brimonidine drug class

adrenergic agonist, antiglaucoma agent

Brimonidine contraindication

Hypersensitivity, concurrent MAOIs, use in children <2 yo

Brimonidine Box warnings

None

Brimonidine Briggs

Limited human data - probablt compatible

Bimatoprost brand name

Lumigan, Latisse

Bimatoprost drug class

Prostaglandin, antiglaucoma agent, Cosmestic agent for eyelash growth

Bimatoprost indication

Ocular hypertension, open-angle glaucoma, hypotrichosis of the eyelashes

Bimatoprost contraindication

Hypersensitivity

Bimatoprost box warnings

None

Bimatoprost briggs

No human data - probably compatible

Dexmethylphenidate brand name

Focalin

Dexmethylphenidate drug class

CNS stimulant C-II

dexmethylphenidate indication

ADHD

dexmethlphenidate contraindication

Hypersensitivity, MAOI use, history of drug dependence, tics or history of tourette syndrome, glaucoma

dexmethylphenidate box warnings

abuse, misuse, addiction

dexmethylphenidate briggs

no human data - animal data suggest low risk

Buprenorphine brand name

suboxone, zubsolv

buprenorphine drug class

Opioid partial agonist & antagonist combo, C-III

buprenorphine indication

opioid use disorder

buprenorphine contraindication

hypersensitivity

buprenorphine box warnings

none

buprenorphine briggs

compatible

phentermine brand name

adipex-P, Lomaira

phentermine drug class

Centrally Acting Appetite Suppressant, C-IV

phentermine indication

Obesity

phentermine contraindication

hypersensitivity, history of drug abuse, moderate-severe HTN, hyperthyroidism, use in agitated states, glaucoma, cardiovascular disease

phentermine box warnings

None

phentermine briggs

contraindicated

Olanzapine brand name

Zyprexa

Olanzapine drug class

Atypical antipsychotic

Olanzapine indication

Bipolar disorder, schizophrenia, depression

Olanzapine contraindication

Hypersensitivity

Olanzapine box warnings

Mortality in elderly patients with dementia-related psychosis; DRESS

Olanzapine briggs

Maternal benefit - embryo-fetal risk

Risperidone brand name

Risperdal

Risperidone drug class

Atypical antipsychotic

Risperidone Indication

autistic disorder, Bipolar I disorder, Schizophrenia

Risperidone contraindication

Hypersensitivity, agents that increase QTc interval

Risperidone box warnings

Mortality in elderly with dementia

Risperidone Briggs

Maternal benefit - embryo-fetal risk

Carbamazepine brand name

Tegretol

Carbamazepine drug class

Anticonvulsant

Carbamazepine indication

Seizures, neuropathic pain

Carbamazepine contraindications

Hypersensitivity, history of bone marrow depression, MAOIs, nefazodone

Carbamazepine box warnings

Agranulocytosis, aplastic anemia, dermatologic reactions (especially in asians), screen for HLA-B15:02

Carbamazepine briggs

Maternal benefit - embryo-fetal risk

Oxycarbazepine brand name

Trileptal

Oxycarbazepine drug class

Anticonvulsant

Oxycarbazepine indication

Partial seizure

Oxycarbazepine contraindication

Hypersensitivity

Oxycarbazepine Box warning

None

Oxycarbazepine briggs

Limited human data - animal data suggest risk

Anastrozole Brand name

Arimidex

Anastrozole drug class

Aromatase inhibitor

Anastrozole indication

Breast Cancer

Anastrozole contraindication

Hypersensitivity, pregnancy

Anastrozole box warnings

None

Anastrozole Briggs

Contraindicated

Lithium brand name

Eskalith, Eskalith CR, Lithobid

Lithium drug class

Antimanic

Lithium indication

Bipolar disorder

Lithium contraindication

Severe debilitation, dehydration, or sodium depletion, significant cardiovascular disease, significant renal impairment, concomitant diuretic therapy

lithium box warnings

Lithium level monitoring required

Lithium briggs

Human data suggests risk

Pramipexole brand name

Mirapex, Mirapex ER

Pramipexole Drug Class

Dopamine agonist

Pramipexole Indication

Parkinson Disease, Restless Leg Syndrome

Pramipexole Contraindication

Hypersensitivity

Pramipexole Box warnings

None

Pramipexole Briggs

Limited human data - animal data suggest low risk

Clobetasol brand name

Impoyz, Temovate

Clobetasol drug class

topical corticosteroid

Clobetasol indication

Skin disorders, plaque psoriasis

Clobetasol contraindication

Hypersensitivity