Molecular Genetics Lecture 1 - Intro

What is genetics?

the study of genes, their variants and how genes are transmitted from one generation to the next (heredity or inheritance) in living organisms

What is molecular genetics?

biochemical basis of genetics and associated technologies

______ carry the blueprint for an organism

genes/DNA

What do genes do?

encode proteins that specify tissues, organs and phenotypes of a whole organism

What controls the phenotype?

genes

What are phenotypes/traits?

observable feature or characteristics

What leads to an altered phenotype?

mutation

Over ______ genetics diseases in humans are caused by mutations in single genes (cystic fibrosis, Huntington, etc.)

10,000

Can we repair or edit the genetic code (DNA)?

CRISPR/Cas9

What are some applications of genetics?

discover genes associated with phenotypes, understand mechanisms of how those genes cause diseases, develop diagnostic tests for early detection of diseases, develop therapy, develop treatment for cure, biotechnology, GMOs

What is GLP-1?

modified GLP1 peptide

______ represents the complete set of all the DNA from an organism.

genome