exam 1 - cytokines

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Last updated 2:49 PM on 9/9/26
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15 Terms

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released by Th1

IFN-gamma, IL-2, TNF-alpha

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Th1 is associated with

cell-mediated immunity

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function of IL-2

T cell growth factor

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IFN-gamma function

activate macrophages

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IL-2 + IL-12 causes what

IFN-gamma production by CD4+ cells

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released by Th2

IL-4, 5, 6, and 10

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Th2 is associated with

humoral immunity and IgE production

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IL-4 function

differentiation into Th2 cells

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IL-5, 6, 10, and 21 function

plasma cell differentiation

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Tfh secrete

IL-5, 6, 10, and 21

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Th17 secretes

IL-17

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IL-17 function

increases ICAM-1 expression, secretes IL-8, and differentiation of stem cells into neutrophils

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IL-8 function

recruits neutrophils to the site of infection

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Tregs secrete

TGF-beta and IL-10

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TGF-beta function

anti-inflammatory