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Classifying vs. understanding human variation
Contrasts grouping people into categories versus explaining the origins and causes of human variation.
The Great Chain of Being
The belief that all living things occupy a fixed position on a continuous hierarchical scale.
Carolus Linnaeus
Naturalist who classified humans as Homo sapiens with geographic varieties based on natural history.
Johann Friedrich Blumenbach
Founder of physical anthropology who proposed five human racial categories from a common ancestor.
Ethnocentrism
Judging other cultures by the standards of one's own culture.
Scientific racism
"The misuse of science to argue that human races are natural
Polygenism
Doctrine that different races descended from different origins or 'Adams'.
Monogenism
Doctrine that all humans share a single common origin.
Typology
Reducing continuous variation into idealized categories.
Eugenics
Movement promoting selective breeding to preserve or improve perceived human traits.
Cranial Index
Maximum skull breadth divided by maximum skull length ×100.
Anthropometry
Measurement of the human body and its proportions.
Franz Boas
Anthropologist who demonstrated environmental influences on human biology and challenged racial typology.
Plasticity
Ability of an organism to modify biology or behavior in response to environmental change.
Cline
a gradual change in the frequency of a biological trait or gene across a geographic area, rather than an abrupt difference between distinct groups.
Tuskegee Study of Untreated Syphilis
Unethical U.S. study in which African American men with syphilis were denied treatment.
Institutional Review Board (IRB)
Committee that reviews research involving human participants for ethical protection.
Race
"A socially constructed system of categorizing people
Ethnicity
"Grouping based mainly on shared culture
Population
A community of individuals who usually mate with one another.
Discordance
Traits inherited independently that do not predict one another.
Concordance
Traits that tend to vary together.
Genetic determinism
Belief that genes overwhelmingly determine traits or behavior.
Embodiment
Process by which social and environmental conditions become biologically incorporated over the life course.
Morbidity
Rate of disease in a population.
Mortality
Rate or proportion of deaths in a population.
Racial-genetic determinism
Claim that genetic differences explain racial health disparities.
Social Determinants of Health Model
Model emphasizing social and environmental conditions as drivers of health.
Intergenerational Inheritance of Health Model
Model describing how parental and early-life environments influence later health.
Adaptation
Biological change that improves survival or reproduction in an altered environment.
Homeostasis
Maintenance of stable internal conditions.
Allostasis
Maintaining stability through context-dependent physiological change.
Acclimatization
Reversible physiological adjustment over days to weeks.
Developmental adaptation
Developmental changes that improve fitness in a particular environment.
Genetic adaptation
Heritable evolutionary change produced by natural selection.
Human Energy Allocation Model
Model stating that finite energy must be divided among competing biological functions.
Metabolic health
Risk profile for cardiovascular disease and type 2 diabetes.
Subcutaneous adipose tissue (SAT)
Fat beneath the skin with relatively lower inflammatory activity.
Visceral adipose tissue (VAT)
Fat surrounding organs that produces more inflammatory molecules.
Food security
"Reliable access to sufficient
Dietary adequacy
Extent to which nutrient intake meets nutritional requirements.
Physical nutritional status
Biological measures of nutritional health such as body composition or blood markers.
Body mass index (BMI)
Weight in kilograms divided by height in meters squared.
Epidemiological transition
Shift from infectious to chronic diseases as leading causes of death.
Stressor
Environmental factor that triggers an allostatic response.
Acute stress
Short-term activation of the stress response.
Chronic stress
Long-term activation of the stress response that damages health.
Autonomic nervous system
Controls involuntary bodily functions.
Sympathetic nervous system
Division responsible for fight-or-flight responses.
Parasympathetic nervous system
"Division promoting rest
Neurotransmitter
Chemical messenger acting across short distances between cells.
Hormone
Chemical messenger carried through the bloodstream.
HPA axis
Hypothalamus-pituitary-adrenal stress response pathway.
Cortisol
Glucocorticoid hormone that mobilizes energy and suppresses immunity.
Ultraviolet radiation (UVR)
"Solar radiation affecting skin
Melanin
Pigment that protects tissues from UV damage.
Melanocyte
Cell that produces melanin.
Eumelanin
Dark pigment providing strong UV protection.
Pheomelanin
Red-yellow pigment providing little UV protection.
MC1R gene
Gene regulating eumelanin production.
Folate
Vitamin essential for cell growth and red blood cell production.
Vitamin D
Vitamin produced partly through UV exposure that aids calcium absorption.
Tanning response
UV-induced increase in eumelanin production.
Allen's Rule
Cold-adapted animals have shorter limbs; warm-adapted animals have longer limbs.
Bergmann's Rule
Cold-adapted animals tend to have larger bodies.
Vasoconstriction
Narrowing of blood vessels to reduce heat loss.
Vasodilation
Widening of blood vessels to increase blood flow.
Thermogenesis
Heat production by the body.
Non-shivering thermogenesis (NST)
Heat production without muscle shivering.
Brown adipose tissue (BAT)
Heat-producing fat rich in mitochondria.
Indirect calorimetry
Measurement of metabolic rate using oxygen consumption and carbon dioxide production.
Hunting's response
Alternating vasoconstriction and vasodilation during cold exposure.
Hypobaric hypoxia
Reduced oxygen availability due to low atmospheric pressure at altitude.
Acute mountain sickness
Short-term illness after rapid ascent to high altitude.
Chronic mountain sickness
Loss of altitude adaptation in long-term high-altitude residents.
Candidate gene approach
Tests genes chosen for known biological relevance.
Genome-wide association study (GWAS)
Genome-wide scan for genetic variants associated with traits.
Hypoxia-inducible factors (HIF)
Proteins coordinating responses to low oxygen.
Arterial saturation (SaO2)
Percentage of hemoglobin carrying oxygen.
Hypoxic ventilatory response (HVR)
Immediate increase in breathing caused by hypoxia.
Vital capacity
Maximum air exhaled after a full inhalation.
Residual volume
Air remaining in lungs after maximal exhalation.
Immune system
Body's defense against infectious disease.
Innate immunity
"Rapid
Adaptive immunity
Specific immune response that develops after antigen exposure.
Antigen
Substance that triggers a specific immune response.