general anesthetic

isoflurane

IH, odor

MOA:

• amplify GABA

use:

• induction, maintenance

AE:

• CV , resp depression

• PONV

• malignant hyperthermia

contraindication:

• fam hx malignant hyperthermia / PONV

treatment of malignant hyperthermia

IV dantrolene

propofol

IV

MOA:

• depress CNS through GABA amplification

• no analgesia

use:

• induction, maintenance

• sedation

AE:

• pain or burn at IV site

contraindication

• allergy to soy or egg

• lipid metabolism disorder

nurse:

• aseptic technique

ketamine

IV

MOA:

• produce analgesia w/o opioid receptor

use:

• critical ill pt

• lower BP / HR

BBW:

• delirium

• hallucination

• unpleasant dreams

nurse:

• monitor recovery closely

vecuronium

neuromuscular block

MOA:

• suspend nerve impulse at neuron junction

use

• skeletal paralysis

• intubation

• mechanical ventilation

AE:

• mild urticaria

• erythema

contraindication

• hypersensitivity

nurse:

• recurarization

recurarization

return of muscle weakness after pt recovery

succinylcholine

neuromuscular blockage

MOA:

• only depolarizing

use:

• tracheal intubation

• rapid sequence intubation

AE:

• malignant hyperthermia

• BBW → cardiac arrest

contraindication:

• hx of malignant hyperthermia

• pre-existing hyperkalemia

midazolam

BZD

MOA:

• short-acting IV

use:

• adjunct

BBW

• profound respiratory depression

reversal

• flumazenil

fentanyl

opioid

use:

• supplement sedation / general

AE:

• resp depression

• urine retention

reversal:

• naloxone