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_____ are solutions administered directly into a patient's vein to maintain or restore fluid balance, provide nutrients, or correct electrolyte imbalances.
IV Fluids
fluids are broadly categorized based on their ______ and their effect on the__________.
Composition,
body's fluid balance
Major types of IV Fluids
Crystalloids
Colloid solutions
Blood Products
most common types of IV fluids
Crystalloid Solutions
Crystalloid solutions contain ________________-
water, electrolytes, sometimes glucose
they are called _____ because they contain small molecules that can easily pass through cell membranes.
crystalloids
types of crystalloid
isotonic
hypotonic
hypertonic
These fluids have the same osmolarity (concentration of solutes) as blood plasma, meaning they do not cause fluid shifts between compartments (intracellular or extracellular
isotonic solutions
types of isotonic Solution
Normal Saline 0.9% sodium Chloride
LR
Ringer’s solution
A simple solution of sodium chloride and water.
Normal Saline 0.9% Sodium chloride
Contains sodium, chloride, potassium, calcium, and lactate (which is metabolized to bicarbonate), mimicking the electrolyte composition of blood plasma.
Lactated Ringer’s Solution
what does LR contain
sodium, chloride, calcium , potassium, lactate
mimics the electrolyte composition of blood
Similar to Lactated Ringer’s but lacks lactate.
Ringer’s solution
Common uses of Isotonic Solution
fluid resuscitation
surgical patients
electrolyte imbalance
burns
These fluids have a lower osmolarity than plasma, meaning they will cause water to move into the cells, hydrating them.
hypotonic solution
types of hypotonic solution
0.45% sodium chloride (half normal saline)
D5W (5% dextrose in water)
Contains half the amount of sodium chloride as normal saline.
0.45% Sodium Chloride
once administered, the dextrose is metabolized, and it becomes effectively a hypotonic solution.
D5W
Common uses if Hypotonic Solution
Cellular hydration
Diabetec ketoacidosis (DKA)
Hyponatremia
for patients with intracellular dehydration, such as those with hyperglycemia).
Hypotonic Solution
Hyponatremia means
low sodium
These fluids have a higher osmolarity than plasma, so they pull water out of cells and into the extracellular space.
Hypertonic Solutions
types of Hypertonic Solution
3% sodium chloride
D10W
A solution that provides both water and glucose.
D10W
uses of Hypertonic Solution
severe hyponatremia
Cerebral edema
Shock state
______contain larger molecules (such a___ or ___) that are too large to pass through cell membranes. They help maintain _______ drawing water into the blood vessels.
Colloid Solutions
Protein, starches
Blood Volume
Common types of Colloids
albumin
Dextran
Hespan (Hydroxyethyl Starch)
A protein solution that is the most common colloid used.
Albumin
A glucose-based polymer solution.
Dextran
A synthetic colloid.
Hespan, hydroxyethyl starch
Common use of Colloid solution
hypovolemic shock ( severe blood loss or fluid loss)
severe burns or large fluid loss
plasma volume expansion in pt. with low albumin levels ( Cirrhosis, nephrotic syndrome)
e: Colloids are less commonly used now in general practice due to the potential for side effects such as ______ or ______. They are more commonly used in intensive care or emergency situations
kidney injury, Allergic reaction
Types of Blood Products
whole blood
packes RBC
Plasma
platelets
Cryoprecipitate
Contains red blood cells, plasma, white blood cells, and platelets. Rarely used as whole blood due to the ability to separate components.
whole blood
Red blood cells separated from whole blood.
Packed RBC
· The liquid portion of blood, used to treat clotting disorders.
plama
Used to treat bleeding disorders due to low platelet counts (e.g., in leukemia).
platelets
· Contains clotting factors and fibrinogen, used for bleeding disorders.
Cryoprecipitate
Uses of Blood products
severe anemia
major trauma or surgery
clotting disorders
platelet deficiencies
DEHYDRATION
Isotonic fluids NS , LR
restore extracellular fluid volume
SEVER BLOOD LOSS (HEMORRHAGIC SHOCk)
Colloid Albumin Dextran | Blood products
restore BV and improve oxygen-carrying capacity
HYPERNATREMIA
Hypotonic 0.45% NaCl, D5W
move water into cells and dilute sodium levels
HYPONATREMIA
hypertonic fluids 3% Nacl
raise sodium levels + correct fluid imbalance
SURGICAL | POST-OP FLUID RESUSCITATION
Isotonic LR NS
replace fluid loss during surgery or anesthesia
DIABETIC KETOACIDOSIS
Isotonic then hypotonic (NS then 0.45% Nack )
rehydrate + correct electrolye imbalance
CEREBRAL EDEMA
Hypertonic fluids 3% NaCl
reduce brain swelling