Virology: Additional Viruses

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HPV: characteristics

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1

HPV: characteristics

ds DNA virus, non-segmented non-enveloped humans targets epithelial cells

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2

HPV: disease

acute or chronic infection warts: lack of immune response -clearance can occur with development of immune response cancer: cervical, penile, anal -viral proteins activate cell growth and suppress apoptosis

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3

HPV: transmission

sex

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4

HPV: vaccine

yes (for some strains) -against structural proteins from types of associated with cancer

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5

HPV: treatment

drugs: yes (rarely used) cryotherapy/acid to remove warts

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6

HPV: prevention

safe sex, vaccination

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7

Coronaviruses: characteristics

+ss RNA virus, non-segmented -proof reading enzyme (doesn't evolve as fast as it could) -has really large genome enveloped

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8

Coronaviruses: types

SARS, MERS, SARS-2 (COVID) -zoonotic

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9

Coronaviruses: disease

acute infection common cold -along with rhinoviruses, adenoviruses, RSV -circulate in humans

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10

Typical coronaviruses

restricted to upper respiratory tract replicate @ 33-35 C usually receptors other than ACE-2 generate poor memory immune responses no vaccine or drugs

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11

Coronaviruses: variants?

yes- different mutations

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12

Coronaviruses: SARS-2

can go systemic (ACE-2) memory immune responses? -can block some innate immune responses -cytokine storm

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13

Coronaviruses: SARS-2 treatment

drugs: yes vaccine: yes -recombinant -RNA

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14

Monkey Pox: characteristics

ds DNA virus, non-segmented enveloped

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15

Monkey Pox: disease

acute infection pox: filled with virus

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16

Monkey Pox: vaccine

yes (limited supply) many potential vaccines based on smallpox vaccine -evidence for cross immunity

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17

Monkey Pox: drugs

none

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18

Monkey Pox: prevention

vaccination, avoid infected individuals

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19

Arboviruses: characteristics

humans are dead end host

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20

Arboviruses: transmission

insects -replicates inside the insect vector

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21

Arboviruses: treatment

no drugs limited vaccines -yellow fever

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22

Zoonotic: characteristics

humans are dead end host

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23

Zoonotic: rodents

Lassa, Hanta

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24

Zoonotic: Ebola

unknown vector passive immunization vaccines?

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25

Zoonotic: Various mammals

rabies- neurological infection

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26

Zoonotic: Rabies

"universal" virus passive immunization vaccine (post exposure)

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27

Diarrheal Viruses

rotavirus (vaccine), norovirus, norwalk virus, astrovirus

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28

Prions

infectious protein -no nucleic acid -convert normal host protein -can't do anything about them

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29

Prions: transmission

consumption

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