Diseases of the Posterior Pituitary

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7 Terms

1
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What is SIADH?

  • Syndrome of inappropriate anti-diuretic hormone secretion

    • Hyper secretion of ADH; too much

2
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What are the clinical manifestations of SIADH

  • enhanced renal water retention

  • Hyponatermia

  • Serum hypo-osmolality

3
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What is Diabetes Insipidus?

  • Insufficiency of ADH

  • Clinical manifestations of polyuria and polydipsia

  • Partial or total inability to concentrate the urine

4
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What is neurogenic diabetes insipidus?

  • Hypothalamus or pituitary gland fails to produce ADH, kidneys can’t concentrate urine, water isn’t reabsorbed

  • Insufficient amounts of ADH

5
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What is nephrogenic diabetes insipidus?

  • Kidneys can’t respond to ADH due to faulty receptors in collecting ducts; inadequate response to ADH

6
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What is psychogenic diabetes insipidus?

  • Excess water ingestion causing diluted blood and excess urine

  • Occurs due to psychological factors like stress, anxiety, schizophrenia

7
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What are the manifestations of diabetes insipidus

  • enhanced water excretion

  • Hypernatremia

  • Serum hyperosmolality