[PHARMACEUTICAL DOSAGE FORMS] MANOR

PROVERBS 16;3

C) Isotonic

1. Solution which has the same osmotic pressure and pH as human fluid is:
   A) Saturated
   B) Hypertonic
   C) Isotonic
   D) Hypotonic

A) Peroxidase

2. Acacia reproduces color with some substance due to the presence of:
   A) Peroxidase
   B) Acid
   C) Impurities
   D) Any of the above

D) Solution with maceration

3. Spirit of peppermint is prepared by:
   A) Simple solution
   B) Chemical reaction
   C) Distillation
   D) Solution with maceration

D) None of the above

4. Brandy is made from:
   A) Molasses
   B) Fermented malt juice
   C) Fermented juice of grapes
   D) None of the above

E) All of the above

5. Preservative added to syrup:
   A) Glycerin
   B) Benzoic acid
   C) Sodium Benzoate
   D) Methyl Paraben
   E) All of the above

C) Ointments

6. Levigation is often applied in:
   A) Syrups
   B) Solutions
   C) Ointments
   D) Tinctures

D) 5%

7. General formula for infusions uses a strength of:
   A) 10%
   B) 15%
   C) 20%
   D) 5%

B) Antihistamine

8. One of the following is not a biological product:
   A) Serum
   B) Antihistamine
   C) Toxoid
   D) Anti-toxin

B) 50%

9. Concentration of "Diluted Alcohol" by volume is:
   A) 10%
   B) 50%
   C) 70%
   D) 20%
   E) 85%

B) Talc

10. Aromatic water may be prepared by triturating the oil with:
    A) Acacia
    B) Talc
    C) Kaolin
    D) None of the above

C) Glycerin

11. Phenol produces a clear solution with:
    A) Water
    B) Ammonia
    C) Glycerin
    D) Liquid petrolatum

C) Comminution

12. One of the following is not a process of extraction:
    A) Maceration
    B) Digestion
    C) Comminution
    D) Decoction
    E) Percolation

E) All of the above

13. Separation of immiscible liquids may be carried out by:
    A) Glass syringe
    B) Pipette
    C) Separatory funnel
    D) Florentine receiver
    E) All of the above

B) Solutions

14. Liquid preparations that contain one or more chemical substances usually non-volatile dissolved in water is:
    A) Emulsions
    B) Solutions
    C) Lotions
    D) Syrups

D) 10%

15. Triturations usually have a strength of:
    A) 5%
    B) 1%
    C) 15%
    D) 10%
    E) None of the above

B) Levigation

16. A small scale comminution is:
    A) Maceration
    B) Levigation
    C) Digestion
    D) None of the above

D) Distillation

17. Process of converting a liquid into vapor and condensing back to liquid is:
    A) Sublimation
    B) Condensation
    C) Evaporation
    D) Distillation

A) Incineration

18. Chemical change caused by heat:
    A) Incineration
    B) Evaporation
    C) Sublimation
    D) All of the above

C) Dover's powder

19. One of the following has strength of 10% opium:
    A) Laudanum
    B) Paregoric
    C) Dover's powder
    D) All of the above

B) Sodium stearate

20. Glycerin suppositories are solidified by the use of:
    A) Stearic acid
    B) Sodium stearate
    C) Glycerol triacetate
    D) White wax

E) All of the above

21. Tablet is the preferred form as dosage form because of:
    A) Stability
    B) Economy
    C) Precision of dosage
    D) Convenience
    E) All of the above

D) None of the above

22. Liquid preparations representing water-soluble principles of animal and plant drugs are:
    A) Spirits
    B) Tincture
    C) Fluidextracts
    D) None of the above

A) Benzoic acid

23. The preservatives for juices:
    A) Benzoic acid
    B) Sodium benzoate
    C) Alcohol
    D) Glycerin

C) U. S. P. or N. F. statement of required purity

24. Purity means:
    A) Purified coloring substance
    B) Pure food and drugs act
    C) U. S. P. or N. F. statement of required purity
    D) Substance requires purification

D) Surfactants

25. The HLB system is used to classify:
    A) Flavors
    B) Colors
    C) Perfumes
    D) Surfactants

B) Weak electrolytes

26. Most drugs are:
    A) Strong electrolytes
    B) Weak electrolytes
    C) Non-electrolytes
    D) Highly ionic

B) Palatability

27. The usual purpose of chilling medication prior to administration is to increase:
    A) Absorption
    B) Palatability
    C) Stability
    D) Ionization

C) Rabbits

28. The U. S. P. Pyrogen test is performed on:
    A) Dogs
    B) Guinea pigs
    C) Rabbits
    D) Cats

A) Cold place

29. According to the U. S. P. standard, a refrigerator may be used to store pharmaceutical which specify storage in a:
    A) Cold place
    B) Controlled room temperature
    C) Dark place
    D) None of the above

B) Trituration

30. The process of grinding substances to a very fine powder is termed:
    A) Levigation
    B) Trituration
    C) Sublimation
    D) Percolation
    E) Maceration

A) Douche

31. An aqueous solution which serves as a cleansing or an antiseptic agent directed against a part or into a cavity of the body is a/an:
    A) Douche
    B) Enema
    C) Gargle
    D) Spray

B) 10 volume peroxide

32. The official hydrogen peroxide solution U. S. P. is also known as:
    A) Diluted peroxide
    B) 10 volume peroxide
    C) 15 volume peroxide
    D) 30 volume peroxide

A) Petrolatum rose water ointment

33. A synonym for cold cream, U. S. P. is:
    A) Petrolatum rose water ointment
    B) Vanishing cream
    C) Wool fat ointment
    D) Rose water ointment

B) Hermetic container

34. Container impervious to air:
    A) Light-resistant tight container
    B) Hermetic container
    C) Single dose container
    D) All of the above

B) Not perceptible to touch

35. The term "impalpable" refers to a substance that is:
    A) Colorless
    B) Not perceptible to touch
    C) Greasy
    D) Tasteless

C) A vitamin

36. Cyanocobalamin is:
    A) A steroid
    B) Hallucinogen
    C) A vitamin
    D) An enzyme

C) Vegetable oils

37. The non-aqueous vehicle used in injection:
    A) Alcohol
    B) Glycerol
    C) Vegetable oils
    D) Liquid petrolatum

B) Ophthalmic solutions

38. Which one of the following solutions should be sterile when dispensed:
    A) Tinctures
    B) Ophthalmic solutions
    C) Spirits
    D) Syrups
    E) None of the above

D) All of the above

39. Bulk powders are:
    A) Triturations
    B) Dentrifices
    C) Douche powder
    D) All of the above

D) None of the above

40. Oleoresins are:
    A) Volatile oils
    B) Waxes and resins
    C) Fixed oils and resins
    D) None of the above

A) A colored substance

41. A chromagen is:
    A) A colored substance
    B) Certified dye
    C) A dye fixative
    D) A precursor of color

A) Anti-histamine

42. Alcohol is a specific potentiating agent when used with:
    A) Anti-histamine
    B) Penicillin
    C) Aspirin
    D) Sulfonamide

B) Oxidation at double bond

43. Rancidity of fats may be due to:
    A) Impurities
    B) Oxidation at double bond
    C) Reduction to alcohol
    D) Hydrogenation at double bond

C) A drug profile

44. This is a tool for monitoring drug utilization:
    A) A drug receipt
    B) A drug invoice
    C) A drug profile
    D) Prescription

A) Diagnose diseases and prescribe prescription drugs

45. These are roles of the pharmacists except:
    A) Diagnose diseases and prescribe prescription drugs
    B) Recognize self-limiting diseases
    C) Recommend OTC drugs
    D) Advise patients on expected drug side effect

C) Diagnosis of diseases

46. These are developing trends in a pharmacist's function except:
    A) Influence the physician in choice of drugs
    B) Use of generics
    C) Diagnosis of diseases
    D) Advise the physician on dosage regimens

A) Nonprescription drugs

47. OTC drugs are:
    A) Nonprescription drugs
    B) Prescription drugs
    C) Regulated drugs
    D) Potent drugs

D) Label

48. This represents the quality of the product and the professionalism of the compounding pharmacists:
    A) Price of the medicine
    B) Name of the drug store
    C) Name of the prescriber
    D) Label

D) Compliance

49. Recovery of an ambulatory patient depends upon this factor in this medication:
    A) Brand product
    B) Generic product
    C) Expenses
    D) Compliance

D) Polyoxyalkalene derivatives

50. Spans and Tweens are:
    A) Phospholipids
    B) Glycoside
    C) Highly polymerized mannuronic acid anhydrides
    D) Polyoxyalkalene derivatives

C) Filtering

51. Which of the following is not a method of splitting emulsions:
    A) Centrifuging
    B) Adding electrolytes
    C) Filtering
    D) Heat

B) Pounds per square inch gauge

52. The term PSIG in reference to aerosols means:
    A) Per square inch of glass
    B) Pounds per square inch gauge
    C) Atmospheric pressure
    D) Propellant safety in glass

A) Bitter after taste

53. A disadvantage of sodium saccharin as a sweetening agent is:
    A) Bitter after taste
    B) Solubility in water
    C) Poor strength compared to glucose
    D) Poor strength compared to gulein

B) Light-resistant container

54. According to the USP, the instruction protect from light in a monograph indicated storage in a:
    A) Dark place
    B) Light-resistant container
    C) Amber glass bottle
    D) Hermetic container

A) Relief from gas

55. The pharmacist may suggest Riopan Plus in place of Riopan when the patient desires:
    A) Relief from gas
    B) Greater antacid capacity
    C) A chewable tablet
    D) Lower sodium levels

A) mL of solvent required to dissolve 1 gram of solute

56. Solubility of a substance may be expressed in several ways. When a quantitative statement of solubility is given in the USP, it is a generality expressed as:
    A) mL of solvent required to dissolve 1 gram of solute
    B) G of solute soluble in 1 mL of solvent
    C) G of solute soluble in 100 mL of solvent
    D) mL of solvent required to dissolve 100G of solute

B) Sufficient activity to be outside USP monograph requirement

57. The expiration date on a pharmaceutical container states "Expires on July 1997". This statement means that by that expiration date, the product may have lost:
    A) 50% of its activity
    B) Sufficient activity to be outside USP monograph requirement
    C) 5% of its activity
    D) All of its activity

D) All of the above

58. Which of the following agents is/are available in a sublingual dosage form?
    A) Isosorbide dinitrate (Isordil)
    B) Glycerin
    C) Hydrogenated ergot alkaloids (Hydergine)
    D) All of the above

B) Crystals of Theophylline

59. Upon exposure to air, Aminophylline solutions may develop:
    A) A gas
    B) Crystals of Theophylline
    C) A precipitate
    D) A straw color

A) Multivalent metal

60. A chelate must always contain a:
    A) Multivalent metal
    B) Triple bond
    C) Amine group
    D) Ethylenediamine group

D) All of the above

61. Official forms of water include:
    A) Water for injection
    B) Sterile water for injection
    C) Bacteriostatic water for injection
    D) All of the above

C) Subcutaneous injection

62. Insulin preparations are usually administered by:
    A) Intradermal injection
    B) Intramuscular injection
    C) Subcutaneous injection
    D) Intravenous

B) Intravenous

63. "Winged" needles are most closely associated with which type of injections?
    A) Intramuscular
    B) Intravenous
    C) Subcutaneous
    D) Length of needle

A) Intermittent therapy

64. The term piggyback is most commonly associated with:
    A) Intermittent therapy
    B) Total parenteral nutrition
    C) Intravenous bolus
    D) Flow intravenous infusions

B) Partially filled parenteral bottles with 50 to 150 mL volumes

65. The designation "minibottles" refers to:
    A) 10-30 mL glass vials
    B) Partially filled parenteral bottles with 50 to 150 mL volumes
    C) Any parenteral bottle with a capacity of less than 1 mL
    D) Vials with a capacity of less than 10 mL

A) Intravenous infusions

66. The term venoclysis is most associated with:
    A) Intravenous infusions
    B) Intrathecal injections
    C) Intravenous injections
    D) Peritoneal dialysis

B) 5.0%

67. Which of the following commonly available large-volume dextrose solutions for intravenous use is isotonic?
    A) 2.5%
    B) 5.0%
    C) 10%
    D) 50%

A) An automatic device for self-injecting

68. The busher injection is:
    A) An automatic device for self-injecting
    B) A pre-filled syringe unit
    C) Wyeth's cartridge injection unit
    D) A disposable syringe and needle system

D) B and C only

69. Valium (diazepam) is available in which of the following dosage forms?
    A) Elixir
    B) Tablet
    C) Injection solution
    D) B and C only

A/C) Maalox and Mylanta

70. This antacid containing mixture of aluminum and magnesium hydroxide is marketed under the name of:
    A) Maalox
    B) Amphojel
    C) Mylanta
    D) Titralac

B) Cannula

71. The shaft portion of the needle is called the:
    A) Bevel
    B) Cannula
    C) Lumen
    D) Hub

B) Tinctures

72. Alcoholic and hydroalcoholic solutions prepared from vegetable materials or from chemical substances, prepared usually by maceration and percolation.
    A) Extracts
    B) Tinctures
    C) Fluidextracts
    D) Elixirs

B) Fluidextracts

73. Concentrated (1g/mL) alcoholic or hydroalcoholic solutions representing the therapeutically active principles of vegetable drugs prepared by percolation process:
    A) Extracts
    B) Fluidextracts
    C) Tinctures
    D) Elixirs

A) Elixirs

74. Clear, pleasantly flavored, sweetened hydroalcoholic liquids intended for oral use as flavors and vehicles for substances:
    A) Elixirs
    B) Tinctures
    C) Fluidextract
    D) Extracts

B) Gargles

75. Aqueous solutions used for treating the pharynx and nasopharynx by forcing air from the lungs through the solution which is held in the throat:
    A) Mouthwashes
    B) Gargles
    C) All of the above
    D) None of the above

C) Solutions

76. A homogenous mixture in which the molecules of the solute are dispersed among those of the solvent:
    A) Suspensions
    B) Emulsions
    C) Solutions
    D) All of the above

D) All of the above

77. Purified water may be prepared by:
    A) Distillation
    B) Ion-exchange resin
    C) Reverse osmosis
    D) All of the above

D) All of the above

78. Syrups may be prepared by:
    A) Solution with heat
    B) Agitation without heat
    C) Percolation
    D) All of the above

D) All of the above

79. Spirits, popularly known as essences, are alcoholic or hydroalcoholic solutions of volatile substances prepared by:
    A) Simple solution
    B) Distillation
    C) Chemical reaction
    D) All of the above

C) Emulsion

80. A two-phase system prepared by combining 2 immiscible liquids, one of which is uniformly dispersed throughout the other:
    A) Suspension
    B) Solution
    C) Emulsion
    D) Magma

B) Suspension

81. Preparations containing finely divided drug particles uniformly distributed throughout a vehicle in which the drug exhibits a minimum degree of solubility:
    A) Emulsion
    B) Suspension
    C) Solution
    D) None of the above

A) Strong iodine solution

82. Lugol's solution is:
    A) Strong iodine solution
    B) Potassium iodine oral solution
    C) Povidone-iodine solution
    D) None of the above

D) Ethylene glycol

83. The following solvents are used in the preparation of oral solutions, syrups and elixirs except:
    A) Alcohol, USP
    B) Purified water, USP
    C) Propylene glycol
    D) Ethylene glycol

B) Sodium lauryl sulfate

84. An example of an anionic emulsifying agent is:
    A) Benzalkonium chloride
    B) Sodium lauryl sulfate
    C) Polyethylene glycol
    D) Magnesium trisilicate

C) Cholesterol

85. The following substances produce which emulsions, except:
    A) Gelatin
    B) Egg yolk
    C) Cholesterol
    D) Casein

D) All of the above

86. Suppositories are prepared by:
    A) Melting from a melt
    B) Compression
    C) Hand rolling
    D) All of the above

B) Urethral suppositories

87. Bougies is another term for:
    A) Vaginal suppositories
    B) Urethral suppositories
    C) Rectal suppositories
    D) None of the above

C) Absorption ointment base

88. Anhydrous lanolin is a/an:
    A) Hydrocarbon ointment base
    B) Water-removable ointment base
    C) Absorption ointment base
    D) Water-soluble ointment base

C) All of the above

89. Cold cream is a/an:
    A) Water in oil (w/o emulsion)
    B) Absorption ointment base
    C) All of the above
    D) None of the above

B) Hydrophilic petrolatum

90. The following are hydrocarbon ointment base except:
    A) Petrolatum
    B) Hydrophilic petrolatum
    C) White petrolatum
    D) Mineral oil

A) Ointments

91. Medicated or non-medicated semisolid preparations intended for external application:
    A) Ointments
    B) Lotions
    C) Liniments
    D) All of the above

C) 3 and 4 only

92. Which of the following sterilization methods is (are) used for heat-labile pharmaceutical preparations?
    1) Moist-heat sterilization
    2) Dry-heat sterilization
    3) Sterilization by filtration
    4) Gas sterilization
    A) 1, 3 and 4
    B) 1 and 3 only
    C) 3 and 4 only
    D) 3 only

B) Stimulant laxative

93. Castor oil is a/an:
    A) Saline laxative
    B) Stimulant laxative
    C) Bulk-forming laxative
    D) Emollient laxative

A) 1, 3 and 4

94. The saline cathartics:
    1) Act by increasing the osmotic load of the gastrointestinal tract
    2) Act by local irritation on the intestinal tract
    3) Are salts of poorly absorbable anions and cations
    4) Water soluble and are taken with large amounts of water
    A) 1, 3 and 4
    B) 2, 3 and 4
    C) 1 and 3
    D) 1 and 4

B) Capsules

95. Solid dosage forms in which one or more medicinal and/or inert substances are enclosed within a small shell or container generally prepared from a suitable form of gelatin:
    A) Tablets
    B) Capsules
    C) Troches
    D) Pastilles

C) Effervescent salts

96. Granules or powders consisting of sodium bicarbonate, a suitable organic or inorganic acid and other ingredients are known as:
    A) Dusting powder
    B) Dentrifices
    C) Effervescent salts
    D) Insufflations

D) 000

97. Which of the following capsule size is the largest?
    A) 1
    B) 0
    C) 00
    D) 000

B) Sorbitol

98. What substance is/are added to render soft gelatin capsules elastic or plastic like?
    A) Mineral oil
    B) Sorbitol
    C) Carnauba wax
    D) All of the above

A) Tablets

99. Widely used solid dosage forms of medicinal substances usually prepared with the aid of suitable pharmaceutical adjuncts by compression or molding and contain medicinal substances with or without suitable pharmaceutical adjuncts:
    A) Tablets
    B) Bulk powders
    C) Capsules
    D) Divided powders

C) 2 only

100. Which of following is / are true of buccal tablets?
     1) Intended to be dissolved beneath the tongue
     2) Provide absorption of drugs that are destroyed by the gastric juice
     3) Dissolved very promptly to give rapid drug effects
     A) 1 and 2
     B) 2 and 3
     C) 2 only
     D) 1, 2 and 3