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Addiction is defined as a __________ disorder characterized by compulsive drug seeking and use despite known adverse consequences.
chronic relapsing
Addiction involves functional changes to brain circuits involved in __________, stress, and self-control.
reward
The D2 dopamine receptor levels in individuals with a history of cocaine use are __________ compared to those without such a history.
lower
The initial euphoria produced by drugs is often followed by __________ effects that differ by the type of drug used.
other
People use substances to 'feel good' because drugs can produce intense feelings of __________.
pleasure
Social anxiety, stress, and depression may lead individuals to use substances in an attempt to feel __________.
better
High levels of __________ can pressure individuals to try or continue using drugs, especially in teenagers.
performance expectations
Teenagers are particularly at risk for substance use due to __________ pressure from peers.
social
Biological factors that affect addiction can include genetics, stage of __________, and gender or ethnicity.
development
Genes and environmental factors together account for about __________ of a person's risk of developing an addiction.
40 to 60%
Environmental factors regarding addiction include influences from family, school, and the __________.
society or neighborhood
The more risk factors an individual has, the greater the chance that taking a drug will lead to __________.
substance use and addiction
Protective factors are those that reduce a person's overall risk for __________.
addiction
Home and family environments, such as parental drug use, can significantly increase a child's __________ risk.
drug
Peer influence during the teen years can lead even those without risk factors to try drugs for the __________ time.
first
Substances change the way the brain works, and some people's brains are more __________ to problematic substance use.
vulnerable
Binge intoxication is a stage associated with the __________, where pleasurable effects of a substance are experienced.
basal ganglia
Withdrawal is associated with the __________, where ordinary rewards lose their power.
extended amygdala
The craving for a substance after a period of abstinence is associated with the __________.
prefrontal cortex
Trauma can be categorized into acute, chronic, and __________ trauma.
complex
Adverse childhood experiences can lead to long-term negative health and emotional consequences and increase the risk of __________.
substance use
Experiencing emotional maltreatment in childhood increases the risk of __________ in the future.
problematic substance use
Early use of substances is thought to increase the likelihood of developing __________ problems later on.
serious
All addictive substances cause increases in the release of the neurotransmitter __________.
dopamine
Social and environmental factors, alongside neurobiology, have implications for substance use and __________.
addiction
The stress endured from adverse childhood experiences affects brain development, contributing to __________ health issues.
long-term negative
The three stages of problematic use can be thought about as a repetitive __________.
cycle
Addiction is now recognized as a true __________ disorder affecting brain function and behavior.
medical
Factors that increase the likelihood of addiction vary from person to person, with no __________ factor being the sole determinant.
single
Substance use disorders are influenced by both __________ and biological factors.
environmental
A significant part of addiction prevention is understanding the various __________ behind a person’s substance use and treatment.
factors