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What are the levels of organizations?
cell to tissue to organ to organ system to organism
How do cells recognize and communicate with each other?
recognize each other by the extracellular matrix and communicate through the cell membranes
What are desmosomes?
button-like welds that join opposing cell membranes, rivet cells into a strong sheet but allows substances to pass freely through the intercellular space, intracellular filaments attach the plasma membranes of both cells, found in sheets of tissue that are subjected to severe stress (heart muscle)
What are tight junctions?
intracellular junctions that are tight enough to block transport of substances through the intercellular space, specialized membrane proteins that bond cells tightly together like a set of belts, found in epithelial layers that separate two kinds of solutions
What are gap junctions?
channels or pores through membranes of two cells and across the intracellular space, allow electrical communication between cells and for the flow of ions and small molecules, found in areas like the heart where rapid communication is a necessity
What are the four tissue types?
epithelial, connective, muscular, and nervous tissue
What is epithelial tissue?
tissue that makes up coverings
What is simple?
one layer
What is stratified?
more than one layer
What is pseudostratified?
only in columnar cells, have weird column shapes
What is squamous?
flat/circular
What is cuboidal?
cube/square
What is columnar?
column/rectangle
What is simple squamous epithelium?
single layer of flattened cells, very leaky so excellent for diffusion, linings of blood vessels (alveoli of lungs)
What is stratified squamous epithelium?
several layers of flattened cells stacked upon each other, can be keratinized or non-keratinized
Where are stratified squamous epithelium tissues found?
areas that are subject to abrasion; outer layer of skin, linings of vagina, anus
What does keratinized mean?
has protein keratin that confers waterproofing and helps resist friction and bacterial invasions (outer layer of skin)
What does non-keratinized mean?
occurs in areas that stay moist but are subject to wear and tear (linings of anus, vagina, mouth, esophagus)
What is a basement membrane?
where cells are in a junction with each other
What is simple cuboidal epithelium?
found in areas where the main function is secretion, endocrine glands
What are endocrine glands?
glandular epithelium that work in groups, secrete products directly in the bloodstream (without duct)
What is stratified cuboidal epithelium?
found in areas such as the sweat glands, exocrine glands
What are exocrine glands?
glandular epithelium that work in groups, secrete products into a duct (sweat glands secreting sweat)
What are simple columnar epithelium?
found in areas such as the intestinal lining (mucosa layer), finger-like projections in intestinal lining are called villi and are involved in absorption and secretion (digestive enzymes), goblet cells
What are goblet cells?
glandular epithelium that works individually, secrete mucus that helps lubricate foodstuffs as it passes down through the intestines
What is pseudostratified ciliated columnar epithelium?
found lining the upper respiratory tract (trachea and bronchi), functions to sweep mucus and foreign objects up and out of the airway using cilia located on the luminal/apical surface of the cells
What are the matrix fiber types of connective tissue?
collagen, elastic, reticular
What is loose (areolar) connective tissue?
very thin and delicate tissue; no patter or arrangement of fibers, used to hold organs in place and to bind epithelial tissue to the underlying tissues, contains all three fibers, has fibroblasts and macrophages
What are fibroblasts?
cell type in loose areolar connective tissue; secrete the proteins of the extracellular matrix (makes fibers)
What are macrophages?
cell in loose areolar connective tissue; phagocytic, amoeboid cells that function in the immune system
What is adipose connective tissue?
fat; specialized type of loose in which adipocytes (fat cells) enlarge and store lipids
What are the functions of adipose connective issue?
insulation against heat loss, pads/cushions against injury, provides nutrient storage
What is dense regular connective tissue?
matrix is a thick interlacing matted network of collagen fibers in parallel bundles, allowing for great tensile strength; no space between fibers; tendons and ligaments
What are tendons?
not elastic but are flexible, cable-like cords that connect skeletal muscle to bone
What are ligaments?
somewhat elastic and connect bone to bone
What is dense irregular connective tissue?
matrix is a thick interlacing matter network of collagen fibers in parallel bundles, allowing for great tensile strength; has fibers in interwoven bundles with more space between them
What is submucosa?
layer between the muscle (muscularis layer) and intestinal lining (mucosa layer); compromised of dense irregular connective connective tissue
What is cartilage?
specialized form of dense connective tissue that is strong but somewhat flexible, forms embryonic supporting skeleton of vertebrates
What is chondroitin sulfate?
very dense, collage fibers embedded in a rubbery matrix; secreted by chondrocytes
What are chondrocytes?
makes cartilage; found in small chambers/spaces of the ground substance called lacuna (hole); also secrete collagen
How does cartilage form the embryonic supporting skeleton of vertebrates?
as embryo ages, the cartilage gets replaced in most areas by bone except in locations such as the ear flaps, trachea, larynx, tip of nose, and end of long bones
Replacement of cartilage with bones happen in what?
all vertebrates except Chondrichthyes (sharks and rays), Myxini (hagfish), Cephalaspidomorphi (lampreys)
What is fibrocartilage?
characterized by a scattering of chondrocytes throughout collagenous fibers (in rows); found in inter-vertebral discus
What do collagen fibers do in fibrocartilage?
give a wavy appearance
What is elastic cartilage?
high number of elastic fibers present, tissue can bounce back into shape, found in areas that need flexible support (ear, esphogus)
What is a hyaline cartilage?
characterized by lack of elastic fibers, does not have ability to bounce back into shape, found in areas that need a more rigid support (ends of the long bones, sternal ends of the ribs, cartilage rings of the trachea that help keep trachea from collapsing)
What is bone?
mineralized connective tissue with a hard, rigid matrix; remains alive, secreting a calcified matrix throughout life
How is bone made?
osteoblasts lay down deposits of calcium phosphate and collage; magnesium, calcium, and phosphate form a substance called hydroxyapatite
What do calcium salts and collagen do for bones?
calcium makes the bone hard and collagen keeps it from being too brittle; give bone strength with some elasticity
What are osteons?
basic structural unit of bone; found in compact bone
Where are NOT true osteons found?
spongy bone; has irregular latticework of thin plates of bone called trabeculae with spaces between filled with red marrow that produces erythrocytes
What are osteoblasts?
build the bone tissue; when trapped in their own matrix, become osteocytes
What are osteoclasts?
function in bone degradation
What are osteocytes?
maintain bone tissue and reside in the spaces known as lacuna, which are surrounded by the matrix secreted originally by the osteoblasts
What is special about osteocytes?
switch with osteoblasts and osteoclasts depending on what cell needs
What are Haversian canals?
channels contain blood vessels and nerves to supply and control the bone cells; run through the matrix
What is a lamella?
located concentrically around the canals that are calcified rings
What is the collective term for Haversian canal and surrounding Lamella?
osteon
What are Canaliculi?
cell extensions that are how lacuna are interconnected
What are the three types of muscle?
skeletal, smooth, and cardiac
What is skeletal tissue?
cylindrical cells, striated, multinucleated, peripheral, unbranched fibers, under voluntary control; makes up large muscle masses that attch to the bones
What does exercise do to muscle cells?
increases their size not number; adults have a fixed number of muscle cells
What is cardiac muscle?
cylindrical cells, striated, up to 2 central nuclei, branched fibers, under involuntary control; found in walls of the heart
What is special about cardiac muscle?
has branched fibers joined by intercalated discs that help speed the relaying of the stimulus for contraction from cell to cell
What is smooth muscle?
spindle-shaped cells, non-striated, single nucleus, unbranched fibers, under involuntary control; found in walls of the alimentary, genital, and urinary tracts and in the walls of arteries and veins; contractions are slower but can stay contracted longer
What is a neuron made up of?
has soma, dendrites, and axon
What is a soma?
cell body of neuron; contains the nucleus and most of the organelles
What are dendrites?
extensions that are responsible for conducting stimuluses into the soma
What is the axon?
extension that is responsible for conducting impulses away from soma
What makes up nerve fibers?
axons and dendrites together
How are nerve fibers bound together outside the central nervous system?
by connective tissue to form nerves
What do nerves do?
send messages from the sense organs to the brain and conduct impulses from the brain and spinal cord to make muscle contract