Pharmacology - Histamine H2 Antagonists: Cimetidine

Flashcards covering key pharmacological information about Cimetidine, its uses, adverse reactions, administration guidelines, client instructions, contraindications, precautions, and drug interactions.

Cimetidine

A histamine H2 antagonist

Therapeutic Uses of Cimetidine

Gastric and duodenal ulcers, heartburn

Adverse Drug Reactions of Cimetidine

Impotence, reduced libido, and gynecomastia

Client Instructions for Cimetidine

avoid smoking and irritating foods, and report signs of gastrointestinal bleeding.

Contraindications for Cimetidine

Known sensitivity and impaired liver function

Precautions for Cimetidine

hepatic or renal dysfunction

Drug Interactions with Cimetidine

Antacids can reduce absorption; cimetidine increases levels of warfarin, phenytoin, lidocaine, and theophylline.

Method of action for Cimetidine

Block histamine receptors in the stomach responsible for secretion of stomach acid