mitosis and cellcycle (exam4)

The basic substructure of chromatin in which DNA is wrapped around a histone octamer core is called the _____.

nucleosome

Spindle poles form in response to the duplication of the _____ at the beginning of mitotic prophase.

centrosomes (centriole pair)

Phosphorylation of internucleosomal ____ activates chromatin condensation.

Histodone H1

The actual division of a cell to produce two cells occurs during _____.

cytokinesis

The major growth of the cell prior to cell division occurs during ____.

G1 Phase

Localization of duplicated chromosomes to the spindle poles is called ______.

Telophase

During cytokinesis a circular band of actin fibers is tightened by the action of ______s until the membrane fuses to produced two new daughter cells.

myosin

Anaphase begins when _____ utilizes its active site cysteine to cut the connection between chromatids to make chromosomes.

separase

Each metaphase chromosome is composed of two identical sister ______s.

chromotids

Complete replication of the chromosomal DNA occurs during _____.

S phase

The kinase that activates processes occurring during mitotic prophase is ____

MPF

Phosphorylation of nuclear ____s disintegrates the nuclear envelope into multiple tiny fragments so as to merge the nucleoplasm with the cytoplasm.

Lamin

______ ends when the chromosomes reach the spindle poles.

anaphase

Regulatory mechanisms to determine competence for chromosomal segregation occurs during ____.

G2 Phase

Bidirectional tension that brings metaphase chromosomes to the midpoint between each spindle pole is accomplished by the action of _______ on spindle fibers.

Dynien

Duplicated chromatids are held in contact to each other during prophase and metaphase by ____.

cohesion

 BOTH reconstitution of two new nuclear envelopes AND  the decondensation of  chromatin they contain  is accomplished through the action of a ______ .

Phosphatase

Spindle fibers attach to condensed chromosomes at the ________ complex.

Kinetochore

Spindle fibers grow out from the spindle poles through the addition of _____ dimers.

tubulin