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The two major divisions of the Skeletal System are __________ and __________.
Axial Skeleton and Appendicular Skeleton. The Axial Skeleton consists of the skull, vertebral column, and thoracic cage, providing the main support for the body and protecting vital organs like the brain and heart. The Appendicular Skeleton includes the bones of the limbs and girdles, crucial for locomotion and manipulation of the environment.
The Axial Skeleton is composed of __________ bones, including the skull, vertebral column, and thoracic cage.
80
The Appendicular Skeleton is composed of __________ bones, including the limbs and girdles.
126
One important function of bones is to provide __________, acting as a framework for the body.
Support
Bones also provide __________, which shields vital organs like the brain.
Protection
Bones act as __________ for muscles, facilitating movement of the body.
Levers
Another function of bones is __________, which involves storing minerals like calcium and phosphorus.
Mineral Storage & Hematopoiesis
Compact bone is dense and arranged in __________, found in the diaphysis of long bones.
Osteons
The porous type of bone that contains trabeculae is known as __________ bone.
Spongy
The __________ of long bones is the shaft of the bone.
Diaphysis
The ends of long bones are known as __________.
Epiphysis
The region between the diaphysis and epiphysis is called the __________.
Metaphysis
The network found in spongy bone is referred to as __________.
Trabeculae
The outer fibrous layer surrounding bones is called __________.
Periosteum
The inner lining of bone cavities is known as __________.
Endosteum
The hollow space inside bones is called the __________ __________.
Medullary Cavity
In children, the growth plate is referred to as the __________ __________, which becomes the line in adults.
Epiphyseal Plate
The central canal of compact bone contains __________ and __________.
blood vessels and nerves.
Small cavities housing osteocytes in compact bone are called __________.
Lacunae
The channels connecting lacunae in bone are known as __________.
Canaliculi
The layers of bone matrix in compact bone are called __________.
Lamellae
____________ lamellae surround the entire bone.
Circumferential
____________ lamellae are found between osteons in compact bone.
Interstitial
____________ lamellae surround the central canal in osteons.
Concentric
____________ canals connect blood supply between osteons in bone.
Perforating
The structural unit of compact bone is called an __________.
Osteon
Osteogenic cells differentiate into __________, which are found in the periosteum and endosteum.
Osteoblasts
__________ are cells that form new bone and are derived from osteogenic cells.
Osteoblasts
____________ maintain the bone matrix and are derived from osteoblasts.
Osteocytes
__________ are multinucleated cells that resorb bone.
Osteoclasts
The enzyme secreted by osteoblasts to facilitate hydroxyapatite deposition is called __________ __________.
Alkaline Phosphatase
The organic composition of bone matrix includes __________ __________, which provides flexibility.
Collagen fibers
The inorganic composition of bone matrix includes __________, which provides strength.
Hydroxyapatite
____________ ossification involves direct bone formation, as seen in the skull.
Intramembranous
____________ ossification occurs when bone replaces cartilage, such as in long bones.
Endochondral
Bone lengthening occurs at the __________ __________.
Epiphyseal plate
The five zones of the epiphyseal growth plate include: Resting Zone, Proliferation Zone, __________ Zone, Calcification Zone, and Ossification Zone.
Hypertrophic
New bone is added to the periosteum through __________ growth.
Appositional
The parathyroid hormone (PTH) increases __________ activity to raise calcium levels in the body.
Osteoclast
____________ inhibits osteoclasts to lower calcium levels in the body.
Calcitonin
__________ indicates low calcium levels, which can lead to muscle spasms.
Hypocalcemia
__________ indicates high calcium levels, potentially causing weak muscles.
Hypercalcemia
Hormones like __________ and __________ stimulate bone growth but later close growth plates.
Estrogen and Testosterone
The hormone that promotes bone lengthening is called __________ __________.
Growth Hormone
____________ (Vitamin D) helps with calcium absorption in the body.
Calcitriol
A __________ (open) fracture is when a bone breaks through the skin.
Compound
A __________ (closed) fracture is when a bone does not break the skin's surface.
Simple
A __________ fracture is when the bone is fully broken.
Complete
An __________ fracture is a partial break of the bone.
Incomplete
A __________ fracture is when the bone is misaligned after breaking.
Displaced
A __________ fracture is when the bone remains aligned after a break.
Non-displaced
Bone __________ is the continuous process of bone replacement.
Remodeling
The first step in bone repair is __________ formation, where a blood clot forms at the fracture site.
Hematoma
The second step in bone repair is the formation of the __________ __________, which serves as a temporary cartilage bridge.
Fibrocartilaginous Callus
The third step in bone repair is __________ __________ formation, where spongy bone replaces cartilage.
Bony Callus
The final step in bone repair is __________ __________, where compact bone replaces spongy bone.
Bone Remodeling
Calcium __________ can lead to various health issues related to bone density and function.
Imbalance