Pharmaceutical Analysis Definition of Terms

Definitions for terminologies used in the laboratory.

Titration

• an act of adding and measuring the volume of titrant used in the assay

Analyte

• chemical substance being analyzed

Titrant

• solution of known concentration

Indicator

• a chemical which changes color at every near point in the titration where equivalent quantities of analyte and titratnt was measured

Stoichiometric/Equivalence Point

• the theoretical point of which equivalent amount of each have reacted

End point

• occurs a sudden change in some property of the reaction mixture

• a change which made apparent use of indicators

Direct

• Uses 1 known solution

Indirect

• uses 2 known solutions

Direct Titration

• the reaction between the unkown compound and the compound with the known concentration

Residual Titration

• excess amount of a compound with a known concentration

• done between two known components

• determine the exact end point when there are sharp color changes

Equivalence Point

• chemical reaction

• between titrant and analyte has reached its equal reaction

End Point

• Physical Change (change in color)