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Incidence
Estimated number of new cases of a disease per year
Prevalence
Estimated number of people currently infected with a given disease per year
Pubic lice (crabs)
Small but visible insects (~1mm) that typically live in pubic hair but can spread to other hairy areas of the skin (move by clinging on to two strands of hair)
Feed on the blood of the host
Possible to acquire either through direct contact or by using an infested person’s bedding, clothing, etc.
Mainly cause itching
Typically treated with insecticidal lotion or removed by shaving
Scabies mites
Infestation with a parasitic mite (Sarcoptes scabiei)
Dig tunnels within the upper layers of the skin, commonly found in hairless areas such as wrists, elbows, between fingers, knees, penis, breasts
Lay their eggs beneath the skin
Cause severe itching and rash on skin
Spreads easily between people
Treated with medicated lotion
Trichomoniasis
Infection of the vagina or male urethra and prostate gland with a single-celled protozoa
In women, infection marked by foul-smelling, greenish, or frothy discharge from vagina, itching and redness, abdominal discomfort, and urge to urinate frequently
Men are usually asymptomatic, though women may also be
Transmission occurs through coitus
Estimated 2 million women develop infection per year
Cured with a single dose of metronidazole
Bacterial STDs
Main examples in US are syphilis, gonorrhea, and chlamydia
Can be fatal (syphilis), impair fertility (gonorrhea & chlamydia)), or facilitate HIV infection (all 3)
All are curable when treated promptly, usually with antibiotics
Syphilis
Spread via direct contact (usually sexual) with infected person in primary or secondary stage
Can be transmitted from mother to fetus
Spread via contact with fluid from sores (chancres) which appear at infection site within 10-90 days
There are 4 stages: primary, secondary, latent, tertiary
Can be diagnosed by clinical signs and symptoms (bacterial fluid in discharge from chancre or antibodies to T. pallidum in blood)
Single large injection of penicillin is curative in first year of infection
Epidemic among heterosexual African Americans in the south and gay/bi men in cities, as well as 13% of all new cases being reported in prisons
Primary syphilis
Chancre appears at infection site within 10-90 days and heals within 3-6 weeks. This is the stage in which the individual is most infectious.
Secondary syphilis
Painless rash following the chancre healing that disappears within a few weeks. Individual is still highly infectious.
Latent stage of syphilis
Bacteria continues to multiply in the body and invades the cardiovascular system, bones, liver, and nervous system. Less infectious during this stage.
Tertiary stage of syphilis
Large ulcers appear on skin or organs after having already covered internal organs. Usually too late to treat at this stage. No longer highly contagious.
Tuskegee Syphilis Study
Significantly eroded minority groups’ trust in US medicine
1932 - study of effects of untreated syphilis began on hundreds of African American men in Tuskegee, Alabama (they were not told they had syphilis)
1947 - penicillin was recognized as standard of care for syphilis, but subjects in study were not informed or treated
1972 - CDC whistleblower told the media, at which point dozens of subjects had died and 22 wives, 17 children, 2 grandchildren had contracted syphilis
gonorrhea
Symptoms develop within 2-10 days of infection
Caused by Neisseria gonorrhoeae bacteria
In women, infection site is cervix
Symptoms include yellow or bloody vaginal discharge, bleeding during coitus, burning sensation when urination
Infection can spread into the uterus and oviducts causing pelvic inflammatory disease (PID) and infertility
In men, infection site is the urethra
Symptoms include discharge of pus from the urethra, pain during urination
Infection can spread to the epididymis or prostate gland (can potentially cause infertility in men)
Used to be treated readily with standard antibiotics, but bacterium has developed drug resistance and CDC recommends all cases be treated with Cephalosporins (special class of antibiotics)
~700,000 new cases reported in US every year; must prevalent in the South
Chlamydia
Most common of all reportable infectious diseases
Usually spread by genital contact, but may be spread by insects in tropical countries (cause of blindness)
Symptoms appear within days
Women - infection appears in the cervix or urethra causing discharge, painful urination
Men - infection appears in urethra causing discharge and burning pain during urination
75% women and 50% men are asymptomatic
Diagnosed from cell samples from penis or cervix, or urine samples
Can be treated with a single dose of antibiotics
Very common in young women - CDC recommends that all sexually active women under 25 be tested once per year
1 in 10 of all adolescent girls is infected
Bacterial Vaginosis
Status as an STD has been up for debate until recently
Normal vaginal microorganisms are replaced by other bacteria
Vaginal pH becomes less acidic
Vagina develops fishy odor, may be itching, pain, and off-white discharge
Many women have no symptoms
Very common among sexually active women (particularly WSW)
Viral STDs
Extremely small infectious particles that enter a host cell
Once in host cell, viral genes take over and either replicate immediately or after being inactive for a period of months to years
NOT treatable with antibiotics, and antiviral drugs are rarely curative and extremely expensive with serious side effects
6 main classes: pox, herpes simplex, CMV, HPV, hepatitis, HIV
Molluscum contagiosum
Skin condition caused by a pox virus
Characterized by small, bump-like growths on the skin which are highly contagious
Virus transmitted by skin-to-skin contact or by contact with infected clothing or towels
Nonsexual transmission is common, especially among children
Does not cause any serious health condition and usually disappears within a year
No serious long-term effects
Herpes
Two herpes viruses (HSV-1 and HSV-2) may be transmitted sexually
Lifelong infection, most common STD by prevalence
17% of Americans aged 14-49 are infected with HSV-2, and 90% are unaware that they’re infected (asymptomatic)
Outbreaks typically preceded by tingling or itching at infection site, and first outbreak may include fever and swollen lymph nodes
Reddish bumps or cluster of spots appear, which turn into blisters within 24 hours, or cracks in the skin
Blisters break leaving sores or ulcers that leak clear discharge containing viral particles (may be painless or mildly itchy)
Diagnosed via lab tests on samples from sores or blood
Treated with acyclovir (Zovirax), available as a topical ointment and the more effective oral tablets
Considered incurable with current therapy
HSV-1
Commonly causes oral herpes, often in form of “fever blisters” or cold sores on lips
May be spread by sexual or nonsexual contact, can be transmitted through touch
Infections of this type have been increasing, possibly due to the popularity of oral sex
Less severe version
HSV-2
Common cause of the more serious genital herpes
Usually transmitted by anogenital contact
Initial symptoms occur within 2 weeks after exposure (outbreak of sores at infection site)
Genitals are most frequently affected sites (penis, labia, clitoral hood, vaginal walls)
Most serious outbreak occurs the first time an individual is exposed
HSV-2 recurrent outbreaks
Primary herpes infection typically resolves within 2 weeks and the sores disappear
Virus remains inert within nerve cell bodies
Later outbreaks typically less severe and less frequent
Virus mainly transmitted during outbreaks, but can also happen between them
Cytomegalovirus (CMV)
DNA virus related to HSV
Most people don’t show symptoms (estimated 50-80% of population infected with it at some point)
Very easily transmitted in bodily fluids
Daycare and nursery school workers are at risk
Mother-to-fetus transmission is possible
Human papillomaviruses (HPV)
100 different types of DNA viruses, 30 of which are sexually transmitted
Viruses infect cells lining urogenital tract or skin near genitalia, can remain inactive or trigger cell division leading to genital warts or sin lesions
Many infected people are asymptomatic
Genital warts are highly infectious and usually painless, don’t cause serious health problems, 90% caused by types 6 and 11
Infection with types 16 and 18 is the main cause of cervical cancer (70%), and linked to anal, mouth/throat, vulval cancer
Not likely for mother to pass along to fetus
Most common STD in the US by incidence (50-57% of sexually active individuals)
Most infected individuals eventually clear the virus from their bodies and become noninfectious to others within 2 years of initial infection
Gardasil - 1st vaccine against HPV types 6,11,16,18
Hepatitis viruses
Viruses that attack the liver - Hep B, followed by Hep A, are the most likely to be sexually transmitted
Vaccines available against both types:
Combined: 3 injections over 6 months
Costs $120 on average without insurance
Hepatitis B
DNA virus that can be transmitted via sex or contaminated blood
Symptoms include jaundice
Most people recover, but some become “chronic” and remain infectious
Treated via drugs taken for months (suppress symptoms but don’t get rid of the virus)
Hepatitis A
RNA virus transmitted most often by fecal-oral route (sexual or nonsexual transmission)
Similar symptoms to Hep B but milder
Disease cannot progress to chronic state and individual does not remain infectious after recovery - no specific treatment
AIDS (Acquired Immune Deficiency Syndrome)
First described in 1981, fatal if left untreated → now an epidemic across the world
Caused by HIV (human immunodeficiency virus) - an RNA virus
Evolved from similar virus that infects chimps in west-central Africa, spread to humans around the 1950s, first major outbreak in gay communities in SF, LA, and NYC in late 1970s
AIDS is the name of the syndrome acquired after the HIV virus becomes active - not everyone infected with HIV develops AIDS today
When the level of CD4 cells in blood is at or below ~200/uL, the person is considered to have AIDS
Symptoms: acute flu-like condition; after latent period, opportunistic infections, cervical cancer, lymphoma, wasting
Diagnosed through blood test (antibodies to virus or DNA test)
Treated through combination of several oral antiviral drugs (HAART) - not curable
Preventative care through PrEP has been highly effective
HIV
Present in high concentrations in semen and vaginal fluid
Transmission occurs more readily in penis-to-vagina or penis-to-anus directions, risk of transmission to receptive partner is 5x higher for anal sex than coitus due to micro-tears in anus being more likely
Presence of existing STDs increases risk
Virus mainly targets CD4 lymphocytes
Seroconversion occurs 6 weeks - 6 months after infection
Symptoms subside after antibodies form and person enters asymptomatic period for 7-10 years
Level of CD4 cells in blood gradually decline from normal level of 1000/microlitier to ~200/uL, when the person is considered to have AIDS
Disproportionately affects MSM and African American communities
childhood sexual expression
Children are curious about sex
Some children engage in solitary sexual activity (autoerotic exploration)
Interpersonal sexual activity between youth
Most common is talking about sex, looking at porn, kissing and hugging, showing genitals
Varying cultural attitudes
Adult-Child Sexual Contacts
Sexual assaults against children have become less frequent because of greater awareness/resources
15% of women and 7% of men report at least one childhood sexual experience involving an adult
80-90% of adult-child contacts involve adult touching child’s genitals
Most likely age bracket for child to have contact with adult male is 7-10 years
Most likely to be relatives and family friends (stepfathers)
Harmful consequences depend on:
cultural dependence (societally criminalized vs normalized)
one-off vs repeated
trusted individual vs stranger
framing - are you told there will be irreparable damage?
how intrusive/violence or threat involved?
Preadolescent sexual activity
Period between 8-12/13 when puberty begins
Most sexual information learned from peers (schools are variable)
Most time is spent in same-sex groups
7% experience coitus before age 13 (red flag, more likely among Black kids)
Adolescent sexual activity
Beginning of phase may correspond with onset of menarche or first ejaculation
Marked by great increase in sexual feelings and behavior
Testosterone levels are strong predictor of when individual will begin partner sex
Lower education and SES level makes individuals more likely to engage in sex before age 15
Coitus among teens increases over time, oral sex is common
Kissing, fondling → noncoital orgasmic contacts → coitus (for some)
Casual sex is becoming more common, and dating is replaced by group outings
Teen pregnancy
4 out of 5 are unintended, & 1/3 end in abortion
For full-term pregnancies, babies are less likely to be breastfed, more likely to have health problems
Father is often out of the picture
Teen birth rates have decreased, though are still disproportionately high for the US compared to other developed nations
Young adult relationship stages
Between puberty and marriage, most young adults spend a portion of time:
Without a sexual relationship
Dating (varying degrees of sexual intimacy)
Cohabiting with eventual marital partner (1yr)
Cohabitation
Increasingly prevalent form of relationships in recent decades
Influenced by demographic factors (age, religiosity, geographic location)
7% of the population (50% either break up or get married within a year)
Marriages preceded by cohabitation end more quickly because those who are more likely to get married without cohabitation are also less likely to divorce (because religion)
40% of couples have children, and 20% last more than 5 years
Marriage
Serves a variety of purposes:
Women viewed as men’s property
Environment for childrearing
Places obligation on others to respect couple’s sexual exclusivity
May bring extended families/clans closer together
Polygamy is commonplace (84% of preindustrial societies)
Over 90% of Americans marry at least once, but the marriage rate is decreasing overall
African American women in inner cities are less likely to be married or cohabiting due to the high incarceration rates of black men
Married women have sex less frequently and have fewer orgasms; marital sex becomes less frequent with increasing age
Emotional satisfaction increases with age for men and decreases for women
Polyamory
People who participate in non-monogamous relationships. Can be many different relationship configurations (triad, etc.)
Companionate Marriage
Form of marriage in which husband and wife are expected to be emotionally and sexually intimate, and engage in social activities together.
This implies some equivalence between husband and wife in distribution of breadwinning, household, & decision-making.
Contrast effects
Occurs in long-term relationships, where men who observe different sexual stimuli or act out different sexual behaviors may find their partner to be less attractive in comparison. This is different from the Coolidge effect, which is about mating and arousal.
Divorce
4 main contributing factors:
Passage of time
1 in 5 first marriages end within 5 years, 1/3 in 10yrs
Woman’s age at marriage (<18)
Ethnicity (highest odds Black, lowest Asian)
Educational level (without degree more likely to divorce)
Dissimilarity shortens marriages
Divorced people suffer higher rates of psychological and physical ill health (less happy, less sexually active, more socially isolated, more prone to substance abuse)
Women suffer severe income drop
Children of divorce experience higher risk of depression, behavior problems, low academic performance, substance abuse, criminality, early sexual activity
Menopause
Average age of menopause occurs at 51
Early menopause can be caused by fewer pregnancies, short cycles, removal of an ovary, not using oral contraceptives, smoking, genetics
Osteoporosis related to menopause (bone density drops with lowered estrogen)
Post-menopausal hormone therapy may be used when women have severe symptoms
Women’s sexual problems
Lack of interest in sex
Inability to experience orgasm
Problems with physiological arousal
Pain during sex
Men’s sexual problems
Premature ejaculation
Anxiety about performance
Pain during sex
Sexual dysfunctions
Impairment in either desire for sexual gratification or ability to achieve it. May be caused by psychological, interpersonal, or physical factors, or a combination. Can occur in any of the first 3 phases of the sexual response cycle (desire, excitement, orgasm).
Primary dysfunction
Lifelong sexual dysfunction, where the individual has never experienced normal functioning.
Secondary dysfunction
Appears after some period of normal sexual function
Situational dysfunction
Sexual dysfunction appears in some circumstances but not in others (eg. with some partners but not others, in partnered vs solitary situations)
Dysfunctions of sexual desire
Category of disruption during the first stage of the sexual response cycle. Only 3% of the general population meets criteria for a clinical disorder regarding lack of desire for sex. Includes:
Hypoactive sexual desire disorder
Sexual aversion disorder
Discrepant sexual desire
Hypersexuality (compulsive sexual behavior)
Hypoactive sexual desire disorder
Disorder where person shows little to no sex drive or interest. Most common female sexual dysfunction in both general and clinical population. Gonadal hormones play strong role in influencing sexual desire in both men and women.
In men, may be treated with testosterone, though side effects can include prostate disease, liver and heart disease, mood problems, balding, lower fertility
In women, low levels of androgens can cause decreased desire and testosterone patches may help
Sexual aversion disorder
Disorder where person shows extreme aversion to, and avoidance of, all genital sexual contact with a partner (usually penile-vaginal contact). More common in women, and is usually treated with psychotherapy.
Discrepant sexual desire
Different levels of sexual activity desired by partners.
Hypersexuality
Excessive sexual desire or behavior that can be caused by some medical conditions, or may be associated with paraphilic disorders. May be treated with psychotherapy and drug therapy (SSRIs, anti-androgens). Behaviors may be related to OCD.
Compulsive sexual behavior
Compulsive cycle related to OCD thought patterns:
craving for sex → ritualized search for sex → sexual behavior → guilt/despair after sexual behavior → …
Dysfunctions of sexual arousal
Category of disruption during the second stage of the sexual response cycle. Includes:
Male erectile disorder (impotence)
Female sexual arousal disorder
Male erectile disorder
Recurrent inability to achieve an adequate penile erection or to maintain it through the course of sexual behavior.
May be partial or complete; primary, secondary, or situation, and becomes much more common as men age.
Affects 50% of men over age 60, and majority of men age 70 or older
Causes:
Behavioral or lifestyle (overweight, lack of exercise)
Medical condition (vascular disease)
Drugs (smoking, alcohol, weed, etc.)
Injuries (spinal chord damage)
Psychological factors (relationship stress, anxiety)
Developmental issues (paraphilias)
Treatment:
Medications that increase responsiveness of erectile tissue to nitric oxide
Hormonal treatments if penile nerves are damaged - Prostaglandin E1
Vacuum constriction system or penile implants
Psychological treatments focus on reducing anxiety and providing reassurance, as well as addressing relationship problems
Prostaglandin E1
Hormonal treatment for men whose penile nerves have been damaged and who are experiencing erectile dysfunction. Can produce erections as long as erectile tissue is intact by heightening sensitivity to nitric oxide. This drug is delivered via self-injection and is very expensive, which results in 50% of men discontinuing treatment.
Vacuum constriction system
Non-drug method to help men with erectile dysfunction that involves placing a constricting cylinder over the penis and then drawing a partial vacuum to cause an erection, increasing bloodflow to the penis. It is among the least expensive forms of treatment and is popular among older men, but it may interrupt sex.
The Eros Clitoral Therapy device (ECTD) is meant to work similarly for women, but is largely ineffective.
Penile implants
Surgical intervention to assist with erectile dysfunction. Most invasive and expensive methods that are likely to damage the erectile tissue, and are usually the last resorts.
Semi-rigid: Soft material implant is inserted in the shaft of the penis, can be bent downwards when not being used for sex
Inflatable prosthesis: Expandable cylinders inserted into penis with saline solution, reservoir, and pump. Cylinders fill with solution to cause an erection. More expensive but more discrete than semi-rigid.
Dysfunctions of sexual orgasm
Category of disruption during the third stage of the sexual response cycle. Includes:
Premature ejaculation
Male orgasmic disorder
Female orgasmic disorder
Premature ejaculation
Persistent and recurrent onset of ejaculation with minimal sexual stimulation. This is the leading form of sexual dysfunction among young and middle-aged men, and can be primary (lifelong), secondary, or situational.
Causes are not well-understood, but may include:
Psychological (eg. early learning context from porn, anticipatory anxiety)
Biological (eg. dysfunction in serotonin receptors)
Treatments:
SSRI treatment
Sex therapy, including CBT, sensate focus technique, stop-start technique, Kegel exercises
Sensate focus technique
A form of sex therapy that involves graduated touching exercises taking sex off the table and focusing on feeling more comfortable engaging in intimacy with one’s partner.
Stop-start method
A sex therapy technique for the treatment of premature ejaculation that involves alternating between stimulating and not stimulating the penis.
Kegel exercises
Exercises to strengthen pelvic floor muscles, with the aim of improving sexual function or alleviating urinary leakage.
Male orgasmic disorder (delayed ejaculation)
Persistent delayed or absent ejaculation during intercourse. This is a fairly uncommon problem that may be a side effect of several drugs (eg. antidepressants) or due to neurological damage. Psychological causes may be possible, but treatment has not been proven effective.
Female orgasmic disorder (anorgasmia)
Persistent or recurrent delay in or absence of orgasm following a normal sexual excitement phase.
10-15% of US women have never experienced an orgasm under any circumstances
Estimated 2/3 of women don’t experience orgasm during coitus
Many women are satisfied with sex despite infrequent or absent orgasms
Causes may include drugs (eg. antidepressants) or medical conditions (eg. diabetes or multiple sclerosis)
Treatment is typically psychological (modify partnered sex, add clitoral stimulation, increase sexual activity, try different positions)
Dysfunctions involving sexual pain
Category of sexual disorders that includes:
Vaginismus
Dyspareunia
Vaginismus
An involuntary spasm of the muscles at the entrance of the vagina NOT due to a physical disorder prevents penetration and sexual intercourse by causing pain.
Caused by the striated muscle of the outer portion of the vagina spasming
Usually treated through both physical therapy involving vaginal dilators that increase in size and psychotherapy that addresses anxiety
Dyspareunia
Coitus causes persistent pain in either men or women (though more common in younger women), usually with a physical basis.
Common causes include:
Developmental malformations
Scars from vaginal tearing
Vaginal atrophy
Acute or chronic vaginal infections (STDs)
Vulvar vestibulitis syndrome (vulval pain)
Endometriosis
Insufficient physiological arousal (especially with older women)
Treatment varies considerably based on cause & diagnosis
infections usually treated with antibiotics, antiviral, or antifungal drugs
Vaginal dryness treated with lubricants or topical estrogen
Endometriosis treated with drugs or surgery
Paraphilias
Group of persistent sexual behavior patterns in which unusual objects, rituals, or situations are required to fulfill sexual satisfaction
Recurrent, intense, sexually arousing fantasies, sexual urges, or behaviors that generally involve:
nonhuman objects
suffering or humiliation of self or partner
children or other nonconsenting persons
Generally all held by men, and are rare conditions
Most do not seek treatment
Comorbidity
The simultaneous presence of two or more medical conditions in a patient.
Fetishism
Fetish is the most important source of sexual stimulation or is essential for satisfactory sexual response
Fetish objects are not articles of clothing used in cross-dressing or devices designed for the purposes of tactile genital stimulation
Generally nonliving objects (eg. shoes, rubber)
Partialism
A type of fetishism that involves typically nonsexual (not primary or secondary sexual characteristics) body parts as as sexually stimulating.
Transvestic fetishism
Individual wears articles of clothing of the opposite sex in order to create the appearance & feeling of being a member of the opposite sex, primarily practiced by cis heterosexual men
Cross-dressing closely correlated with sexual arousal
Often a desire to remove clothing immediately after orgasm
NOT related to being transgender or doing drag
Sadism & masochism
There is a preference for sexual activity as the recipient or provider of pain, humiliation, and/or bondage
In interactions, the infliction or reception of pain/humiliation is the most common source of stimulation or is necessary for sexual gratification
BDSM
Bondage, discipline/domination, sadism, & masochism that is highly scripted, usually consensual, and typically is done in a community with strong safety measures.
Autoerotic asphyxiation
Self-strangulation that produces erotic feelings for the individual, which is highly dangerous and often comorbid with other paraphilias.
Voyeurism
Recurrent or persistent tendency to look at people engaging in sexual or intimate behavior such as undressing, which is associated with sexual excitement & masturbation
No intention to reveal one’s presence or become sexually involved
May not cause perpetrator distress but is a criminal activity
Exhibitionism
Either a recurrent or persistent tendency to expose genitalia to unsuspecting strangers, which is almost invariably associated with sexual arousal & masturbation
No intention or invitation to have sexual intercourse with the witness(es)
May not cause perpetrator distress but is a criminal activity
Frotteurism
Recurrent or persistent preference for touching or rubbing against a nonconsenting person.
Pedophilia
Persistent or predominant preference for sexual activity with a prepubescent child or children (defined by body maturity, not age of preferred partner)
Individual must be at least 16 years old and at least 5 years older than the child or children
Differs from hebephilia (adult attracted to pubescent kids)
Nearly all male, victims usually female between 8-11 years old
Those who act on it are more likely to have been sexually abused as children, and to believe children initiate sexual contact/will benefit from it
Paraphilia Not Otherwise Specified
DSM-V category included for coding paraphilias that do not meet criteria for any of the specific categories
Common examples: telephone scatologia, necrophilia, partialism, zoophilia, coprophilia (feces), urophilia (urine)
Conditioned arousal
Potential mechanism for development of paraphilias
Relies on classical conditioning, where an unconditioned stimulus is paired with physiological arousal and the individual is trained to associate it with arousal
Conditioning experimentally that has been done was weak and easily extinguished
Recidivism
Rate of returning to prison for the same crime after being released the first time
Relatively low for sex offenders, except for those with strongest deviant sexual preferences
Rate for rapists steadily decreases with age, but for child molesters only see decrease after age 50, when testosterone dips
Psychological therapies
In treatment for sex offenders, may include:
Aversion therapy (electric shock therapy)
Covert sensitization/assisted covert sensitization
Cognitive restructuring
Relapse prevention
Not very effective in reducing recidivism
Biological & surgical treatments
In treatment for sex offenders, may include:
Physical castration - low recidivism rates
Chemical castration with anti-androgen drugs
Many treatment programs use combination of hormone therapy and CBT
Autogynephilia
Natal male experiencing sexual arousal at the thought of being or becoming a woman, or having the sex characteristics of a natal female
Cycle of abuse
People with paraphilias who are sex offenders are more likely to have been sexually abused as children.
Seroconversion
Person does not test positive for HIV until antibodies appear in blood (usually 6 weeks - 6 months after infection), at which point they are considered to have HIV.
CD4 lymphocytes
White blood cells targeted by HIV. When level in blood drops to 200 cells/microliter, an individual is considered to have AIDS.
HPV Types 16 & 18
The most severe and concerning types of HPV, which are the main cause of cervical cancer (70%), and linked to anal, mouth/throat, vulval cancer