Anti+Infective+Medications;Antiretrovirals: NRTIs zidovudine (AZT)

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6 Terms

1
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mechanism of action

  • Reduces HIV symptoms and viral replication

2
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therapeutic use

  • First-line antiretroviral

3
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complications

  • Bone marrow suppression

  • Lactic acidosis

  • N/V, diarrhea

  • Hepatomegaly/fatty liver

4
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contraindications

  • Clients with liver disease and bone marrow suppression

  • Caution in pregnancy

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drug/drug interactions

  • Valproic acid, methadone, ganciclovir, rifampicin, phenytoin, amphotericin B, doxorubicin

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education

  • Take on empty stomach with water

  • Take exactly as prescribed