Looks like no one added any tags here yet for you.
What type of bonds does carbon make with other elements?
covalent
carbon chains form skeletons. What types of skeletons can be formed?
they may vary in length and can be straight, branched, or arranged in closed rings (some have double bonds)
define: hydrocarbon
an organic molecule consisting of only hydrogen and carbon; hydrophobic (ex. methane and ethane)
define: functional group
chemical groups that affect molecular function by being directly involved in chemical reactions
What chemical group does -OH belong to?
hydroxyl
What chemical group does C=O belong to?
carbonyl
What chemical group does COOH belong to?
carboxyl
What chemical group does -NH2 belong to?
amino
What chemical group does -SH belong to?
sulfhydryl
What chemical group does PO4 belong to?
phosphate
What chemical group does -CH3 belong to?
methyl
key component of ethanol (alcohol)
hydroxyl
key component of acetone and propanol
carbonyl
key component of carboxylic acid
carboxyl
key component of glycine
amino
key component of cysteine
sulfhydryl
key component of ATP
phosphate
Which chemical group can affect gene expression?
methyl
Which chemical groups are polar?
hydroxyl, carbonyl, carboxyl, amino, sulfhydryl, and phosphate
Which chemical group is non polar?
methyl
Which chemical group is acidic?
carboxyl
Which chemical group is basic?
amino
Which chemical group forms disulfide bridges? (cross links that stabilize protein structure)
sulfhydryl
Which chemical group determines the two groups of sugar?
carbonyl
4 main classes of large molecules of all living things
lipids, proteins, carbohydrates, nucleic acids
define: polymer
long molecule consisting of many similar or identical building blocks linked by covalent bonds (proteins, carbohydrates, nucleic acids)
define: monomer
the repeating units that serve as the building blocks of the polymer. They are smaller molecules
What reaction connects monomers?
dehydration reaction: 2 molecules are covalently bonded together with the loss of a water molecule; -H comes from one monomer and -OH comes from the other
Polymers are converted to monomers in what type of reaction?
hydrolysis: the covalent bond is broken by the addition of a water molecule
What are the monomers of all carbohydrates?
monosaccharides--simple sugars
Most monosaccharides are some multiple of ____.
CH2O
define: aldehyde sugar (carbonyl)
have the C=O at the end of the carbon skeleton
define: ketone sugars (carbonyl)
have the C=O in the middle of the skeleton
All sugars have the same two functional groups…
carbonyl (C=O) and hydroxyl (-OH)
define: structural isomers
compounds that have the same molecular formulas but different structural formulas
What are the 3 hexosugars?
glucose, galactose, and fructose.
What two monosaccharides make up sucrose?
glucose and fructose
What two monosaccharides make up lactose?
glucose and galactose
What two monosaccharides make up maltose?
glucose and glucose
define: glycosidic linkage
a covalent bond formed between 2 monosaccharides by dehydration reaction
What are the two categories of polysaccharides?
storage and structural
What are the two storage polysaccharides?
starch- in plants
glycogen- in animals
What are the two structural polysaccharides?
cellulose- plant cell walls
chitin- exoskeletons of arthropods and the cell walls of fungi
Why can you not digest cellulose?
humans do not have the enzymes to break the beta 1,4 linkages between glucose monomers. Some protists and prokaryotes can digest cellulose, and they are present in the gut of herbivores
has 1-4 B glucose linkages
cellulose
is a storage polysaccharide produced by vertebrates; stored in your liver
glycogen
two monomers of this form maltose
glucose
glucose + ____ form sucrose
fructose
monosaccharide commonly called “fruit sugar”
fructose
“milk sugar”
lactose
structural polysaccharide that gives cockroaches their crunch
chitin
malt sugar; used to brew beer
maltose
structural polysaccharide that comprises plant cell walls
cellulose
What characteristics do all lipids share?
mix poorly with water bc they are hydrophobic
What are the building blocks of fats?
glycerol and fatty acids
What are ester linkages?
bond the forms between the glycerol and fatty acid when a H2O is removed
What element in a fatty acid chain makes it unsaturated?
double bonds because it causes “kinks” or bending of the chain
Why are unsaturated fats liquid at room temperature?
the kinks where the cis double bonds are located prevent the molecules from packing together closely enough to solidify at room temp
What is a trans fat?
an unsaturated fat that has been synthetically converted to a saturated fat by adding hydrogen
4 important functions of fats
energy storage
makes up cell membrane
insulate the body
protects the body
Why are the “tails” of lipids hydrophobic?
they are made of fatty acid chains
define: phospholipid
it consists of a hydrophilic head and hydrophobic tails
has a glycerol attached to a phosphate group
What has a structure of three hexagons and a doghouse?
cholesterol, a steroid
important in cell membranes and a precursor form which other steroids are made
What are two examples of steroids? (hint: sex)
estrogen and testosterone
enzymatic proteins
selective acceleration of chemical reactiosn
transport proteins
transport substances
hormonal proteins (hormones)
coordination of an organism’s actives
receptor protein
response of cell to chemical stimuli
structural protein
support
What are R groups?
side chains which are different for each amino acid
there are 20 side chains
What determines the characteristics of the R groups?
functional groups present
define: peptide bond
covalent bond formed by a dehydration reaction between amino acids
define: dipeptide
2 amino acids joined by a peptide bond
define: polypeptide
many amino acids joined by a peptide bond
Primary Level of Protein Structure
peptide bonds; linear chain of amino acids
Secondary Level of Protein Structure
hydrogen bonds; regions stabilized by hydrogen bonds between atoms of the polypeptide backbone
Secondary Level of Protein Structure (alpha helix)
a coil held together by hydrogen bonding every 4th amino acid
Secondary Level of Protein Structure (beta pleated sheet)
2+ segments of the polypeptide chain lying side by side
Tertiary Level of Protein Structure
R groups; shape of a polypeptide resulting from interactions between R groups
Quaternary Level of Protein Structure
overall protein structure resulting from the aggregation of polypeptide subunits
sickle cell disease
glutamic acid, which is acidic and hydrophilic, is replaced with valine, which is hydrophobic. Therefore, the protein is folded differently which causes aggregation, deforming the blood cell
define: denaturation
when the environment that the protein is in is altering the shape (pH, increase in temp, salt content, etc.)
define: chaperonins
assist in the proper folding of proteins; they are large protein structures that can provide a particular environment (usually hydrophilic) to help a protein fold optimally
The flow of genetic information is from:
DNA→ RNA→ protein (central dogma)
4 nitrogen bases found in DNA
Adenine
Thymine
Guanine
Cytosine
4 nitrogen bases found in RNA
Adenine
Uracil
Guanine
Cytosine
How do ribose and deoxyribose sugars differ?
deoxyribose is missing an oxygen at the 2’ carbon (DNA)
ribose has the oxygen (RNA)
Why are DNA strands said to be antiparallel?
the sugar-phosphate backbones run in opposite 5’-3’ directions from each other
What two molecules make up the “uprights" in DNA?
sugars and phosphates
What molecules make up the “rungs”?
nitrogenous bases