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What are the structures of the muscular system?
muscles, nerves, connective tissue, tendons, blood, and blood vessels
What are the functions of the muscle system?
movement and body heat
What is a tendon?
rope of connective tissue that connects muscle to bone
What is an apenerosis?
sheet of connective tissue that connects muscle to bone or muscle to muscle
What is an epimysium?
membrane on outside of skeletal muscle
What is a fascicle?
bundle of muscle cells
What is a perimysium?
covering on fascicle
What is a muscle fiber?
single muscle cell
What is the order of the muscle from largest to smallest?
muscle→fascicles→muscle fibers→myofibril→filaments
There are multiple __________ in skeletal muscles.
nuclei
What takes up most of the space in skeletal muscles?
myofibril
Sarcolemma→__________
cell membrane
Sarcoplasm→__________
cytoplasm
Sarcoplasmic Reticulum→__________
endoplasmic reticulum
Sarcoplasmic Reticulum keep a high concentration of ____________.
calcium ions
What does active transport use?
energy
What are cisternae?
a lot of calcium ions; part of the endoplasmic reticulum
What are T Tubule's?
continuous with sarcolemma to allow signals (contractions)
What are triad's?
2 cisternae and 1 t tubule
What are the 4 types of filaments?
actin, myosin, tropomyosin, and troponin
What are actin?
thin filament; looks like 2 strands of beads twisted together; each one has a binding site
What are myosin?
thick filament; "testicles on a stick"
What are tropomyosin?
cover binding on actin
What are troponin?
holds tropmyosin in place
What is a sarcomere?
1 unit of contraction
Muscle is striated where muscle is __________.
overlapped
Muscle is not striated where muscle is not __________.
overlapped
What is a neuromuscular junction also called?
synapse
Neuromuscular junction is where the __________ and __________ meet.
nerve; muscle
What is an axon terminal?
end of an exon with vesicles and neurotransmitters
Where is the motor end plate found?
on the muscle
Relaxation requires __________.
energy
What are the steps for relaxation?
1. stop impulse
2. get rid of acetylcholine- acetylcholine storage
3. transport calcium back into sarcoplasmic reticulum
4. filaments go back
Relaxation is __________.
active transport
What are the steps for muscle contraction?
1. actin potential conducted down a motor neuron axon
2. motor neuron terminal releases acetylcholine
3. acetylcholine binds ot acetylcholine receptors on the muscle fiber
4. sarcolemma is stimulated, action potential is generated, impulse is conducted over surface of the muscle fiber and deep into the fiber through the t tubules
5. impulse reaches the sarcoplasmic reticulum and calcium channels open
6. calcium ions diffuse from sarcoplasmic reticulum into cytosol and bind to troponin
7. tropomyosin move and expose sites on active where myosin heads can bind
8. actin and myosin link, form cross-bridges
9. actin filaments are pulled toward the center of the sarcomere by pulling of the cross bridges, increasing the overlap of the thin and thick filaments
10. muscle fiber shortens as contraction occurs
What is rigor mortis?
loss of ATP so you can't move after myosin pulls up
What does nerve gas paralysis cause?
loss of movement
What is the treatment for nerve gas paralysis?
acetylcholine inhibitor- want to keep acetylcholine around
What is Myasthenia Gravis?
decreased acetylcholine receptors
What is the number one symptom of myosinia?
muscle weakness
What is the treatment for myosinia?
acetylcholine inhibitor-want to keep acetylcholine
What are the four sources of ATP?
stored ATP in muscles (very little), creatine phosphate (regenerates ATP), glucose (glycogen), and oxygen (myoglobin)
How much ATP is stored in the muscles?
very little
What does creatine phosphate do?
regenerates ATP
What two sources of ATP make more ATP?
glucose (glycogen) and oxygen (myoglobin
What are the four things for Oxygen Debt?
1. lactic acid
2. myoglobin
3. creatine phosphate
4. ATP
What are the two type of muscle fibers?
type 1 and 2
What kind of fibers are type 1 muscle fibers?
slow twitch
What kind of fibers are type 2 muscle fibers?
fast twitch
Are type 1 (slow) fibers oxidative or glycolytic?
oxidative
Are type 2 (fast) fibers oxidative or glycolytic?
glycolytic
Are type 1 (slow) fibers red or white?
red
Are type 2 (fast) fibers red or white?
white
What is increased in type 1 (slow) fibers?
increased myoglobin=more oxygen
What is decreased in type 2 (fast) fibers?
decreased myoglobin
What kind of respiration is type 1 (slow) fibers?
aerobic respiration for energy
What kind of respiration is type 2 (fast) fibers?
anerobic
What muscle fibers are used for endurance?
type 1 (slow)
What muscle fibers are used for short bursts of speed/power?
type 2 (fast)
What is the training for type 1 (slow) fibers?
increased capillaries for training
What is the training for type 2 (fast) fibers?
increased glycolytic enzyme
What is threshold?
minimum stimulus required for muscle contraction
What is the latent period?
time between stimulus and actual contraction (muscle- 2 milliseconds)
What is the origin?
fixed end of a muscle
What is the insertion?
moveable end of a muscle
What is the agonist?
prime mover; primary muscle responsible for a movement
What is the antagonist?
opposes prime mover (agonist)
What is the synergist?
help prime mover (agonist)
What are the two types of contraction?
isotonic contraction and isometric contraction
What is isotonic contraction?
something moves (ex. sit ups)
What is isometric contraction?
nothing moves (ex. planking)
What are the two type of isotonic contraction?
concentric and ecentric
What is concentric isotonic contraction?
shortening (ex. flexing the bicep)
What is eccentric isotonic contraction?
lengthening (ex. unflexing the bicep)
What are the 4 parts to the systems of levers?
1. lever- rigid bar (bones)
2. force- muscles
3. pivot point- fulcrum (joints)
4. resistance- what you are trying to move
What does the 1st class lever represent?
scissors
What is an example of the first class lever?
triceps
What is the order of a first class lever?
force, fulcrum, resistance
What does the second class lever represent?
like a wheelbarrow
What is an example of a second class lever?
opening the mouth (TMJ)
What is the order for a second class lever?
force, resistance, fulcrum
What does the third class lever represent?
tweezers
What is an example of a third class lever?
bicep
What is the order of a third class lever?
fulcrum, force, and resistance
Minimum stimulus that causes contraction
threshold
Single neuron and the muscle fiber it stimulates
motor unit
Muscle contraction with a change in length
isotonic
Muscle contraction with no change in length
isometric
Immediate source of energy for contraction
ATP
Stored in muscle to regenerate ATP
creatine phosphate
Molecule that stores oxygen in muscle
myoglobin (stronger pull than hemoglobin)
Acid that accumulates with lack of oxygen
lactic
The muscle that has a primary goal in providing a movement is called the __________. Muscles that assist this muscle are called __________ and muscles that oppose the movement are called __________.
agonist; synergist; antagonist
The fixed, stable end of a muscle
origin
The connective tissue covering of a fascicle
perimysium
Cell membrane of a muscle cell
sarcolemma
Neurotransmitter that binds to skeletal muscle
acetylcholine
Thick filament of a myofibril
myosine filament
Molecule that accumulates in aerobic respiration and provides energy for contraction and relaxation
ATP
Which filament binds calcium during contraction?
troponin