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relaxing smooth muscles → decreasing TPR → decreasing blood pressure
How does a vasodilator lowers the blood pressure?
Vasodilators
Drugs that cause dilation of blood vessels resulting in decreased total peripheral resistance lowering the blood pressure.
Step 2
Vasodilators are given at step what of management of hypertension?
Arteriolar vasodilator
Mixed vasodilator
Classification of Vasodilators
Arteriolar vasodilator
This can dilate arteries
Mixed vasodilator
This can dilate arteries and veins
Indirectly:
Hypotension
Reflex stimulation of the heart (reflex tachycardia)
Increase plasma renin
Common adverse effect of vasodilators
Used with a beta blocker or diuretic
Management of antihypertensive drug