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What are 3 tunics of vessels?
tunica intima, tunica media, tunica externa
arteries vs veins (tunics/lumen)?
arteries have thicker tunica media and narrower lumen than. Veins have more elastic and collagen fibers with wide open lumen.
Name 3 basic types of arteries_____
elastic muscular and arterioles
What are the characteristics of elastic arteries?
largest and are 2.5 to 1 cm, Ex: pulmonary trunk, common carotid, and common iliac arteries
What are the characteristics of muscular arteries?
medium, 1cm to 0.3mm, has vasoconstriction with 2 layers being the internal elastic lamina and the external elastic lamina Ex: brachial arteries and coronary
What are the characteristics of arterioles?
0.3mm to 10micro meters, smooth muscle somewhat constricted
Define atherosclerosis_____
progressive disease of elastic and muscular arterioles, presence of atheroma
Define aneurysm_____
Part of the arterial wall thins and balloons out
What is tumor angiogenesis?
Its when cancer cells secrete molecules that cause host cells to release growth factors
Define Blood pressue(BP)
force of blood vessel wall
Define systole
occurs when ventricle contracts
Define Diastole
occurs when ventricles relax
Define Pulse pressure
pressure in arteries added by heart contraction
Define MAP(mean arterial pressure)
average arterial BP across entire cardiac cycle
Define pulse points
where artery may be compressed against a solid structure Ex: radial, common carotid, femoral, dorsalis pedis
What is cerebral edema?
excess interstitial fluid in the brain, MAP>160mm/Hg
What is Deep Vein Thrombosis?
clot or thrombus in the brain, common site is on the calf. Pulmonary embolus is the most serious complication
What is varicose veins
dialted and torturous, non-functional valves causing blood pooling
Define circulatory shock_____
insufficient blood flow to perfuse tissues
Define Resistance
the friction blood encounters, lumensice is also a effect of resistance
Define blood viscosity
resistance of fluid to its flow
Define vessel length
also effects resistance with longer vessels creating more resistance
What is the baroreceptor?
nerve endings that respond to stretch of vessel wall
What does measuring blood pressure do?
measured indirectly using a sphygmomanometer stethoscope placed on the brachial artery. Systole is first “lub” Diastole is last
What is hypertension?
chronically elevated BP
What is hypotension?
chronically low BP
What is orthostatic hypotension?
Drop in BP after sudden standing
2 branches of pulmonary trunk are____
L and R pulmonary arteries
3 branches of the aortic arch are?
Brachiocephalic trunk, left common carotid, and left subclavian artery
What are the branches of the external and internal carotid
external supplies external structures of the skull internal supplies internal skull