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Merkel cell found where?
Basal layer
Meissner’s corpuscles found where?
dermal papillae
Ruffini corpuscle found where?
Deep in dermis, subcutaneous tissue
Pacinian Corpuscle found where?
Reticular dermis, subcutaneous hypodermis, densely packed in hands and feet
Merkel cells detects what?
prolonged light touch, texture, fine points
Meissner corpuscles detect what?
light touch, textural changes, vibration
Ruffini corpuscles detect what?
skin stretching, limb position
Pacinian corpuscles detect what?
Vibration and pressure
Mechanoreceptors include
merkel cell, meissner’s corpuscles, ruffini corpuscles, Pacinian corpuscles
Free nerve endings found where?
epidermis, dermis, around hair
Free nerve endings detect what?
mechanical stimuli, painful and thermal stimuli
Nocrireceptor found where?
Epidermis and dermis, muscles, joints, internal organs
Nocrireceptors detect what?
painful stimuli
merkel cell adapting speed
slow
merkel cell receptive field
small
Meissner’s corpuscles adapting speed
fast
Meissner’s corpuscles receptive field size
small
Ruffini’s corpuscles adapting speed
slow
Ruffini’s corpuscles receptive field size
large
Pacinian Corpuscle adapting speed
fast
Pacinian corpuscles receptive field size
large
Thermoreceptor adapting speed
slow
Thermoreceptor receptive field size
small
Nocrireceptor adapting speed
slow
Nocrireceptor receptive field size
both
Slow adapting
fires impulses continuously for as long as a constant stimulus remains
Fast adapting
Fire an initial burst of signals, quickly drops when continues
main function of epidermis
form protective barrier and replace old cells
main function of keratin
form a tough, protective outer barrier
desmosomes function, where’s it found?
attach adjacent cells to one another, found in stratum spinosum
what layer do keratinocytes lose their nuclei?
stratum granulosum
apoptosis occurs where?
stratum granulosum
stratum granulosum generates large amounts of what
keratin and keratohyalin (both proteins)
lamellar bodies do what
hold and release glycolopids to create waterproof barrier
where is the stratum lucidum
palm, soles, digits
stratum lucidum contains what
eleiden, a clear protein that gives the layer its translucent, shiny look
Top layer of dermis is called and made of what
papillary layer, loose, areolar connective tissue
what forms a mesh in papillary layer
collagen and elastin fibers
Bottom layer of dermis is called and made of what
Reticular layer, much thicker, dense irregular connective tissue
Elastin fibers enable
movement
Collagen fibers provide
structure, binds/hydrates skin