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corresponds with follicular phase
proliferative
corresponds with luteal phase
secretory
mullerian defects
most sensitive marker for menopause
FSH
can use in women WITHOUT a uterus
estrogen only → ↑ endometrial CA, no breast CA risk
used in women WITH a uterus
estrogen + progesterone → ↑ breast CA risk, protective against endometrial/ovarian CA
MC type of AUB
anovulatory → disruption of HPG axis; unopposed estrogen
heavy/prolonged bleeding
menorrhagia
bleeding inbtw periods
metrorrhagia
heavy intermenstrual bleeding
menometrorrhagia
light menstrual bleeding
hypomenorrhea
MCC postmenopausal bleeding
endometrial CA → until proven otherwise
failure of menarche onset by 13
primary amenorrhea
absence of menses > 3 months (if prev menstruated) or > 6 months (if irreg periods)
secondary amenorrhea → MCC is pregnancy
MCC infertility in US
PCOS
disproportionate LH > FSH
PCOS
grouped clear vesicles on erythematous base
HSV
MC bacterial STI
Chlamydia
climactic buboes
LGV
MCC urethritis in men
gram negative intracellular diplococci
gonorrhea
painLESS chancre
syphilis
extreme lower abdominal pain on ovulation
Mittelschmerz
painful menstruation that interferes with ADLs
dysmenorrhea
Venetian blind sign on US
adenomyosis → globally enlarged uterus
*TAH is dx and tx
postcoital/contact bleeding is ______ until proven otherwise
cervical CA
severe dysmenorrhea, chocolate cysts, laparoscopy w bx is definitive
endometriosis
U/L pelvic pain, irregular menses, dyspareunia
ovarian cyst
MC ovarian CA
epithelial (serous cystadenocarcinoma)
MC gynecological CA
endometrial
syndrome assoc w ↑ risk endometrial, ovarian, stomach, pancreatic and prostatic CA
Lynch syndrome
ovarian CA mets to umbilical lymph node
sister Mary Joseph nodule
MC type of endometrial CA
adenocarcinoma → endometrioid
RF: unopposed estrogen
MCC cervical CA
HPV
RF: early onset coitus
procidentia
Uterine prolapse a least 2 cm distal to hymen
replacement of rectum with finger pushing vaginal bulge back through introits to defecate (specific to rectocele)
splinting
ovarian CA tumor markers
CA-125
CA 19-9
clue cells
whiff test → fishy smell
thin milky discharge
↑ pH
BV → metro
white clumpy "cottage cheese" discharge
budding yeast & hyphae on wet prep
vaginal itchiness
RF: abx use, DM
candida vuvlovaginosis → -azoles
frothy pale green discharge → foul smelling
strawberry cervix
↑ pH; pear-shaped organism w tail
trich → metro
parabasal cells
↓ pubic hair
↑ pH
atrophic vaginitis → topical estrogen
purulent cervical discharge
chandeliers sign
PID → doxy + rocephin + metro
MC site of chlamydia in women
cervix → cervicitis
only ABX assoc w OCP failure
rifampin and griseofulvin
MC benign breast dx
fibrocystic breasts → menstrual fluctuation
eczematous, scaling rash on nipple
Paget's
MC type of breast CA
IDC → stellate (star like) on mammo
CI to BC patch
BMI > 30
BBW for significant bone mineral density loss
depo shot
IUD for parous women
mirena
IUD for nulliparous women
skyla
MCC of nipple discharge
intraductal pipilloma
start getting mammograms yearly
45-55 y/o
Nagele's rule
1st day of LMP - 3 months + 1 year & 7 days
GPA classification
G: # times pregnant
P: # births
- full term
- preterm (inc stillborn)
- abortions/miscarriages
- living
fundal height at umbilicus
20 wks
OGTT screening
24-28 wks
GBS screening
35-37 weeks
determines fetal position in 3rd trimester
Leopold's maneuver
blue discoloration of vulva, vagina or cervix
Chadwick's sign
softening of cervix
Goodell's sign
softening of lower uterine segment
Hegar's sign
shortening of cervix during labor (expressed as %)
effacement
distance in cm btw lowest bony portion of fetus & maternal ischial spines
station (0 = at level; + = going through canal)
ED FIRE ERE
engagement
descent
flexion
internal rotation
extension
external rotation
expulsion
tx for chronic HTN during pregnancy
methyldopa
HTN onset > 20 wks gestation & normotensive by 12 week PP
gestational HTN
MC presentation of fetal GBS
meningitis
sensorineural hearing loss
blueberry muffin rash
chorioretinitis
microcephaly
congenital CMV
when to give rhogam
28 wks & w/in 72 hrs delivery
layers that MUST be closed in C section
1st layer uterus, fascia, subQ, skin
leading cause of pregnancy related death in 1st trimester
ectopic pregnancy → MC ampulla; most dangerous is interstitial
cervial change (effacement or dilation) in the absence of uterine contractions
cervical incompétence
abortions
threatened: bleeding w/o dilation
inevitable: bleeding + dilation
incomplete
complete
missed: POC retained
septic: infx of uterus
blighted ovum: sac but no embryo
nitrazine test
ROM test
umbilical cord prolapse
occult = next to baby's head
overt = under baby's head (presenting first)
painLESS hemorrhage in 3rd trimester
placenta previa
unremitting abd/back/uterine PAIN
hypertonic uterus
hemorrhage
placenta abruption → concealed (blood stays in uterine cavity) & external (blood drains through cervix)
egg w no maternal DNA but 1 diploid or 2 haploid sperm
↑↑↑ hCG
cluster of grapes on US
trophoblastic molar pregnancy → hydatidiform
*risk for choriocarcinoma
turtle sign
shoulder dystocia → McRobert, Rubin or Woods maneuver
koplik spots on buccal mucosa
rash starts at hairline
prodrome: cough, coryza, conjunctivitis
comps: blindness
robeola → vit A
forscheimer spots on palate
rash starts on face & fades as it spreads
LAD
rubella
sudden high fever
rash STARTS ON TRUNK
roseola → HHV-6
parotitis
U/L epididymo-orchitis
mumps
U/L asymmetric flaccid paralysis (but MC asx)
transmitted via stool → do stool PCR/cx
destroys anterior grey horn (LMN)
acute polio
CHIKV vs DENV
DENV has hemorrhagic manifestations (bleeding gums)
sharply demarcated rash; butterfly pattern if on face
etiology → GABHS
erysipelas → amox or keflex
strawberry tongue
sandpaper rash sparing palms & soles
pasta lines
scarlet fever → PCV V
jones criteria (CCEPS)
rheumatic fever
poultry workers, pet stores
non-productive cough
chlamydia psittaci
erythema migrans, AV blocks, Bell's palsy, arthritis
Lyme disease
blanching red rash starting on wrists/ankles
RMSF
UTI tx for women
nitro, bactrim, or fosfomycin
asymptomatic bacteriuria tx
nitro, amox, augmentin, keflex
UTI in men tx
bactrim
rabies vax
day 0, 3, 7, 14
MCC of gastroenteritis in the US
seen in daycare & cruises
norovirus
pseudoappendicitis
high fever + rigors
watery → bloody diarrhea
comps: reactive arthritis, GBS
campylobacter → azithro
non-bloody diarrhea after eating eggs or poultry
salmonellosis
bloody diarrhea, lower abd tenderness
comps: toxic megacolon, HUS
shigellosis
faint salmon colored spots on trunk
stepwise fever
typhoid fever