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Assumption for Equilibrium
Random mating, large population, equal fitness and fertility among genotypes, equal gen frequency between sexes
True/False
Domestic animals follow the assumption for equilibrium
False; their populations are heavily in influence by human intervention
Equilibrium
a state in which opposing forces or influences are balanced (don't change between generations)
Why is gene frequency important?
A change in gene frequency may change the mean performance of a population.
What are 4 ways to change a gene frequency?
Drift, mutation, migration, selection (DMMS)
Drift (random change)
-Random statistical fluctuation
- independent of natural selection
- sampling nature of inheritance
Mutation
-biochemical event of a change in DNA sequence
-source of all variation on an evolutionary scale
Migration
- a mixture of populations similar to what often occurred in herds
-bringing in new genetics from outside of the population
-potential to make rapid changes in gene frequencies
selection
-choosing those animals with a high number of desired alleles from the population
-can be 2 types: natural and artificial
artificial selection
Selection by humans for breeding of useful traits
natural selection
Selection that is done by nature in causing the death of the less viable individuals or lower reproduction rates
True/False
Once you switch your population you must use other forces to effect further change.
True
Novel genes
genes that are unique to a species
bottleneck effect
Genetic drift resulting from the reduction of a population, typically by a natural disaster, such that the surviving population is no longer genetically representative of the original population.
Ne
Effective number of breeding animals
Is the fact that domestic populations are not in H-W equilibrium good or bad?
-Bad
-loss of genetic diversity, increased risk of genetic disorders, loss of traits used in the wild
- Pparent=POffspring=no change
Genotype frequency
p+q=1 and p2+2pq+q2=1
P=
frequency of dominant allele
Q=
frequency of recessive allele
N
Total number of events
S
Total number of times events a occurs
T
Number of times event b occurs
A
Chance of event a occurring each time
B
Chance of event b occurring each time
Probability
-likelihood that a particular event will occur
- P= n!/s!t! (a^s•b^t)
Quantitative Traits
-Must be defined numerically to be accurately described, continuous variation
Ex: Feed efficiency, growth rate, speed, milk yield, fat content, agility
Qualitative Traits
-don't need metric definition to be accurately described
-discrete variation
Ex: Horns, colors, Cleft palate, PSS, rate of feathering
Accuracy
-correlation between the estimated and true genotype
-Degree of success in selecting for traits depends on courtesy of estimate
-least accurate due to "fuzzy" observation
Ex: large grouping of arrows on bullseye
Accuracy Genotype
Cumulative effect of all loci
Loci
Location of a gene on a chromosome
incomplete dominance
-Dominant allele does not dominate the recessive allele entirely
-intermediate trait appears in the offspring
Ex: Pink flower with red and white parents
Co-Doninance
When the alleles do not show any dominant and recessive allele relationship
Ex: a flower with white and red alternating
Dominance
-A characteristic in which an allele that expresses its phenotype even in the presence of a recessive allele
Ex: RR= Red
Recessive
-An allele that is masked when a dominant allele is present or expressed without a dominant allele
Ex: Bb or bb
Homozygous
Having two identical alleles for a particular gene
Heterozygous
having two different alleles for a particular gene
Heritability (h2)
-Portion of the phenotypic variance in a population that is due to heredity
Heritability estimates
-indicate the portion of an individual phenotypic superiority or inferiority to transmit to its offspring
- %heritability= variation due to heredity/ variation due to both heredity and environment X 100
-Low heritability: h2<0.20
•survival and Reproductive traits, such as disease distance, litter size, calving interval, longevity in herd
• see more results from managing the environment, rather than selecting for those traits genetically
Moderate Heritability: 0.20
• growth and production traits like weaning weight, average daily gain, milk, yield, birth weight
• pay to select for these traits and manage the environment because these are often the traits you get paid for
High Heritability: h2>0.40
• structural traits in qualitative traits, such as bone, fat, mature size, color, horns
• easy to make fast selection progress because they are not influence much by the environment. However, they may not be terribly valuable in a production setting.
General Heritability Trends
Low heritability, moderate heritability, high heritability
Estimated breeding individual
EBV= h^2 (Pi-Pherd)
Pi
Average performance of individual
Pherd
Average performance of herd
n
Number of records for an individual set of data
R
Repeatability of the trait ratio (typically given)
MPPA
= Pi + nR/[1+(n-1)R] (Pi-Pherd)
Trait Ratio
= Pi/Pherd • 100
True/False
Selection differential can be accumulated over multiple generations
True
Repeatability Estimates
Likelihood that individual will tend to repeat records for a particular trait throughout its life
Ex: milk production at different times in the life of the same individual
Most Probably Producing Ability (MPPA)
is an estimate of producing ability; is a prediction of the next record
True/False
Heritability and repeatability are both average figures and may not be exact for a specific individual or herd
True
Pedigree
A record of an individuals ancestors related to it through its parents
True/False
Data to indicate phenotypic merit of ancestors have ALWAYS been included in "performance pedigrees"
False; they are just now starting to be included
What factors influence the value of performance records of an ancestor?
-the degree of relationship between the ancestor and the individual
-the degree of heritability of the trait
-environmental correlation among animals used in the prediction
-how completely the merit of the ancestors use in the prediction is known
Selection on the basis
The breeder makes a decision to keep or call a sir or dam, based on the average merit of their offspring as compared to the average merit of the prodigy of contemporary sires and dams
True/False
The most effective use of prodigy test and selection for quality traits is to determine if an individual of the dominant phenotype is homozygous or heterozygous.
True
To produce a pure breeding line for a dominant trait what has to happen?
All homozygous, recessive, individuals, and heterozygous and individuals must be removed
True/False
It's much harder to progeny test for recessive genes in litter-bearing individuals
False; it's much simpler
What is the principle involved in the progeny test?
Each progeny receives 1/2 of its inheritance from each parent, and this is a sample 1/2 of each parents breeding value
True/False
The more closely they are related to the individual in question, the more valuable is the information they can apply for selection purposes
True
What does the selection on the basis of sibling test mean?
An individual is kept or cold for breeding based on the average phenotype of its brothers and sisters
Relationships
-parents you offspring R= 0.50
-grandparent to grand-offspring R=0.25
Full Sibling R=0.50
Half Sibling R=0.25
/\P=
Heritability*Selection Differential
Selection differential
Difference between meaning of selected parents, and the population from which they came
How do I increase selection response per year?
-select a trait with a higher hair ability and/or increase variation
-increase accuracy
-increase select intensity
-decrease generation interval
Miniature Horse
-Origin: Northern Europe
-miniature horse
-Stand a max of 34" at the withers
-Dwarfism
-any color
- pets/ pulling carts in mines
Shetland Pony
-origin Shetland island (Scotland)
-Pony
-oldest and smallest of the pony bred
-often sorrels but can be any color
-showing, harness racing and children mounts
Pony of America
-Origin Iowa
-Pony
-cross between Appaloosa and Shetland pony
-any color with Appaloosa type pattering
-Pleasure, horses, and young rides
Stand between 46"- 56"
Welsh Pony
-Origin Wales
-pony
-Thoroughbred and Arabian influence
-coat is commonly black or gray, but can be bay, gray, chestnut
-12 hands
-Red coal mining but now popular for children and small adults
Arabian
-Origin Arabia
-foundational light
-colors are often bay, gray, chestnut, black
-14-15 hands
-Riding horse for endurance
- dished face, high head and tail carriage
- "Father breed" of light horses
Thoroughbred
-Origin, England
-foundational light
-coat colors bay, gray, chestnut, black
-15-16 hands top
-light breed if riding horses known for speed over intermediate distances
-race horses, and speed and horses
Quarter horse
-origin, USA
-light horse
-coat colors, all colors without excessive white
-14-16 hands tall
- light breed of horses and known for speed over short distances
-stock horses, all around horses, rodeo horses, short distance, race horses
Standardbred
-Origin eastern United States
-light horse
-coat colors bay, brown, chestnut, black, gray, roan, fun
-15-16 hands tall
-known as trotters and pacers, these horses are not ridden, but used for harness racing and showing
Morgan
-Origin, United States of America, New England
-light horse
-color colors bay, black, brown, or chestnut
-14-16 hands tall
-known for using temperament, docility, and longevity
-used for stock, saddle, and harness horses
American paint
-Origin, United States of America
-light horse
-originated from quarter horse and thoroughbred conformed horses (other breed types fall into pintos)
-coat colors any base color with white pattern, distinct pattern including Tobiano and overo
-14.2-16.2 hands tall
-stock, pleasure, racing and showing
American Saddlebred
-origin USA
-light horse
- coat colors bay, black, brown, chestnut, gray
-15-16 hands tall
-Head and tail high carriage
- 3 gaits or five gaited horses move with much action and high, stepping, docile and intelligent, have endurance and improve easy writing on rough terrain
-used for pleasure, stock and fine harness horses
Clydesdale
-origin Scotland
- Draft
- bay, brown, or black with white markings, leg feathering is straight silky and heavy
-used for cart pulling and working land
Belgian
-origin Belgium
-draft
-bay chestnut or sorrel
- thicker, curlier hair BUT NOT FEATHERING
- used for cart pulling and working land
Shire
-origin England
-draft
- bat, brown, or black with white markings, feathering is straight, silky, and heavy, neck is long and shoulders are wide and deep
- more athletic, largest of the modern horse, used for pulling carts and working land
Percheron
-origin France
-draft
- dapple gray or black most common but as bay, brown, chestnut or roan
-head is attractive and clean cut, legs have no feathering, good temper
- used for battle, farming and pleasure riding
Trakehner
-origin Trakehnen, east Prussia
-warm blood
-bay, gray, chestnut, or black, bred to be big and more powerful but also athletic
- used for equestrian activities
Holsteiner
-origin Germany
- warm blooded
-bay, gray, chestnut or black
- equestrian sports
Hanoverian
-origin Germany
- warm blood
- most conformational balanced, original carriage horse but now used in English equestrian sports