4Th shifting LE Samplex Gen Path

Increased levels of prolactin, amenorrhea, galactorrhea, loss of libido and infertility is caused by:
a. Somatotroph adenoma
b. Gonadotroph adenoma
c. Lactotroph adenoma
d. Corticotroph adenoma

c. Lactotroph adenoma

Triggered by dilation of the cervix:
a. ADH
b. Both choices
c. Neither
d. Oxytocin

d. Oxytocin

Clinical manifestation of hyperthyroidism EXCEPT:
a. Proximal muscle weakness
b. Tremor
c. Hyperdefecation
d. Cold skin

d. Cold skin

Two weeks after recovery from pharyngitis, a patient presents with edema, hematuria, and malaise. Which is expected?
a. Marked hypoalbuminemia
b. Hypotension
c. Polyuria
d. Increased antistreptolysin O titer

d. Increased antistreptolysin O titer

Compact, lamellar keratin formation (“wet keratin”) is diagnostic of:
a. Papillary craniopharyngioma
b. Adamantinomatous craniopharyngioma
c. Neither
d. Both

b. Adamantinomatous craniopharyngioma

A glomerular immunofluorescent pattern for IgG demonstrating linear immunofluorescence is expected in:
a. Post-streptococcal GN
b. Nephrotic syndrome child
c. A 25-year-old man with hemoptysis and hematuria
d. Progressive chronic renal disease

c. A 25-year-old man with hemoptysis and hematuria

Caused by sudden hemorrhage in the pituitary gland:
a. Empty sella syndrome
b. Sheehan syndrome
c. All of the choices
d. Pituitary apoplexy

d. Pituitary apoplexy

A 5-year-old boy presents with hematuria recurring after sore throat. Most likely diagnosis:
a. IgA nephropathy
b. Alport syndrome
c. Membranoproliferative GN
d. Goodpasture syndrome

b. Alport syndrome

A 50-year-old man with nodular glomerulosclerosis. Most associated lab finding:
a. Hypocalcemia
b. Fixed specific gravity
c. Decreased creatinine clearance
d. Hyperglycemia

d. Hyperglycemia

Produces FSH and LH:
a. Corticotrophs
b. Lactotrophs
c. Gonadotrophs
d. Somatotrophs

c. Gonadotrophs

Consists of modified glial cells and axonal processes extending from hypothalamus through pituitary stalk:
a. Neurohypophysis
b. Anterior pituitary
c. None
d. Adenohypophysis

a. Neurohypophysis

Ischemic necrosis of the anterior pituitary:
a. Sheehan syndrome
b. Pituitary apoplexy
c. All of the choices
d. Empty sella syndrome

a. Sheehan syndrome

Expected EM finding in poststreptococcal GN:
a. Thickened GBM with deposits
b. No changes except fused foot processes
c. Normal GBM with subepithelial “humps”
d. Subendothelial deposits

c. Normal GBM with subepithelial “humps”

What molecular structure extends between podocyte foot processes?
a. Podocin
b. Nephrin
c. Actin
d. CD2AP

b. Nephrin

Causes gigantism in children and acromegaly in adults:
a. Corticotroph adenoma
b. Gonadotroph adenoma
c. Lactotroph adenoma
d. Somatotroph adenoma

d. Somatotroph adenoma

Excess production of ACTH leads to adrenal hypersecretion of cortisol due to:
a. Somatotroph adenoma
b. Gonadotroph adenoma
c. Corticotroph adenoma
d. Lactotroph adenoma

c. Corticotroph adenoma

Produces prolactin:
a. Gonadotrophs
b. Somatotrophs
c. Lactotrophs
d. Corticotrophs

c. Lactotrophs

A 20-year-old woman with nephrotic syndrome shows diffuse thickening of capillary walls. Diagnosis:
a. Minimal change disease
b. Membranous glomerulonephritis
c. FSGS
d. PSGN

b. Membranous glomerulonephritis

Which of the following is NOT a feature of nephritic syndrome?
a. Hypotension
b. Hematuria
c. Proteinuria
d. Azotemia

a. Hypotension