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what is normal calcium range?
8.5 to 10.5
what does calcium do for the body?
helps build strong bones and teeth and allows muscles to contract
what is released when calcium is low?
parathyroid hormone
what is released when calcium is high?
calcitonin
what are the main causes of hypocalcemia?
vitamin d deficiency, low pth, kidney disease, malabsorption disorders, hypoalbuminemia
what is the pathophysiology of hypocalcemia?
low vitamin d or pth causes decreased calcium absorption from food and decreased calcium released from bones
what are the symptoms of hypocalcemia?
paresthesias, tetany, muscle twitching, laryngeal spasms, dysrhythmias, bone pain, and increased bleeding
what are the two pathological findings for hypocalcemia?
positive trousseau's and chvostek's signs
what are the causes of hypercalcemia?
hyperparathyroidism, cancer, excess vitamin d
what is the pathophysiology of hypercalcemia?
excessive pth increases bone reabsorption and renal and intestinal absorptions of calcium
what are the main symptoms of hypercalcemia?
decreased level of consciousness, bradycardia, dysrhythmias, constipation, kidney stones
what is the normal magnesium level?
1.5 to 2.5
what are the causes of hypomagnesemia?
gi losses, renal losses, poor dietary intake, pancreatitis
what is the pathophysiology of hypomagnesemia?
low intake or high renal/gi losses causes decreased magnesium levels. it disrupts enzyme systems and electrolyte balance. leads to increased nerve and muscle excitability
what are the main symptoms of hypomagnesemia?
hyperreflexia, tremors, tetany, tachycardia, nausea, vomiting, confusion, irritability
what are the main causes of hypermagnesemia?
kidney failure, excess magnesium containing medications, diabetic ketoacidosis, hypothyroidism, rhabdomylosis
what is the pathophysiology of hypermagnesemia?
high magnesium blocks calcium at neuromuscular junction which leads to reduced nerve or muscle activity. causes vasodilation and slows heart's electrical system
what are the main symptoms of hypermagnesemia?
flushing/warmth, decreased reflexes, muscle paralysis, respiratory depression, hypotension, bradycardia
what is the normal phosphorus range?
2.5 to 4.5
what two electrolytes are intertwined?
calcium and phosphorus. when phosphorus increases, calcium decreases and vice versa
what are the symptoms and causes of hypophosphatemia?
it mimics hypercalcemia. muscle weakness, confusion, decreased reflexes. caused by malabsorption, diarrhea, and antacid use
what are the symptoms and causes of hyperphosphatemia?
it mimics hypocalcemia. muscle cramps, tingling. caused by renal failure
what is the normal chloride range?
95 to 105
what electrolyte works with sodium?
chloride. they usually change in the same directions
what are the causes of hyperchloremia?
dehydration, kidney problems, and excess saline. can lead to metabolic acidosis
what are the causes of hypochloremia?
vomiting, diarrhea, kidney diseases. can lead to metabolic alkalosis