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Osteoclasts (purpose)
secretes acids and protein-digesting enzymes, regulates calcium in your blood, and assists in remodeling
Bone classification (6)
long, short, flat, irregular, sesamoid, sutural
Long bones (shape and ex)
shaft: humerus, femur, phalanges
Short bones (shape and ex)
cube-like: tarsals and carpals
Flat bones (shape and ex)
plate-like: ribs, scapula, cranial bones
Irregular bones (examples)
vertebrae and facial bones
Sesamoid bones (shape and ex)
round and nodular: in joints, patella
Sutural bones (another name and purpose)
wormian bones, binds
Parts of a bone (12)
epiphysis, diaphysis, processes, foramen, fossa, sulcus, fissure, trochlea, trochanter, facet, spine, ramus
Epiphysis
knobby end, covered with cartilage for articulation
Diaphysis
shaft
processes
bony projections
foramen
openings
Sulcus
small groove
fissure
deep groove
trochlea
cylindrical pully
Trochanter
large, rough projection (ligaments attach to it)
Facet
flat, smooth surface
Spine
pointy process
Ramus
bone with a 90 degree angle
Bone tissue (2)
spongy and compact
Spongy bone
inside of epiphysis, branching bony plates called trabeculae
Compact bone
external wall of bone, continuous matrix with no gaps
Bone layers (4)
periosteum, endosteum, bone tissue, medullary cavity
Periosteum
lines outside of bone: isolates, routes, and growth (dense CT and cellular layer)
Endosteum
lines inside of bone: growth (cellular layer)
Bone tissue
spongy or compact
Medullary cavity
cavity within the shaft of the long bones filled with bone marrow
Two types of medullary cavity
Red and yellow
Red medullary cavity
produces blood cells
Yellow medullary cavity
fat storage
Cell types found in bone tissue (4)
osteoblasts, osteocytes, osteoclasts, osteogenic cells
Osteoblasts (purpose)
produces bone matrix (deposits osteoid, followed by calcium and phosphate)
Osteocytes (purpose)
recycles protein and minerals of matrix, remodels to adapt
fossa
deep pit or depression
Osteogenic cells (other names)
mesenchymal cells, osteoprogenitor cells, stem cells
Osteogenic cells (purpose)
maintains osteoblasts
Osteon (Haversian system)
structural unit of compact bone
lacunae
tiny holes containing osteocytes from osteoblasts
Osteocytes (structure)
bone cells connected by gap junctions
Central canals (Harversian canals)
contains blood vessels and nerve fibers
perforating canals (Volkmann's canals)
transverse connections of central canals
Canaliculi
small canals, gap junctions
Trabeculae of spongy bone (purpose)
adds strength and minimizes weight
Trabeculae of spongy bone (structure)
osteocytes and no canal system
Two types of bone growth/ossification
intramembranous and endochondral
Intramembranous ossification (where?)
develops in membranes of connective tissue
In intramembranous ossification, what do undifferentiated cells become?
osteoblasts
In intramembranous ossification, what becomes trapped?
Blood vessels
In intramembranous ossification, what forms around the blood vessels?
Spongy bone
In intramembranous ossification, how is compact bone formed?
matrix builds and isolates osteoblasts, which are now termed osteocytes, into lacunae
In intramembranous ossification, which type of cells cluster to form osteoblasts?
mesenchymal cells
In intramembranous ossification, what happens in the periosteum?
Outer mesenchymes condense and the surface osteoblasts become less active
endochondral ossification (where?)
develops in rod-shaped cartilage
In endochondral ossification, what happens to mesenchymes
they become chondroblasts
In endochondral ossification, what happens to chondrocytes
they die as the matrix breaks down, then calcify
Factors that affect bone growth, development, and repair
Nutrition, hormones, and exercise
What nutrients affecting bone growth?
vitamin D, vitamin C, vitamin A
Vitamin D
absorbs calcium
vitamin C
collagen production
Vitamin A
bone cell activity
What hormones affect bone growth?
human growth hormone, parathyroid hormone, thyroxine, calcitonin, sex hormones
acromegaly
thickening of jaw and hand bones
hypertrophy
build up of calcium
Major bone functions (4)
support and protection, body movement, blood cell formation, inorganic salt storage
How do bones support and protect the body?
hold up weight, protect vital organs (ribs and cranium), attachments and framework
How do bones help in body movement
bones act as levers
How do bones make blood cells?
red marrow in bones produces blood cells (hematopoiesis)
What inorganic salts are stored in bones? (8)
Beneficial- calcium, phosphorus, magnesium, sodium, potassium
Harmful- lead, radium, stratum
Number of bones in the body
206
Number of bones in a baby
260-270
Divisions of skeleton
axial and appendicular
How many axial bones in the body?
80
Examples of axial bones
skull, backbone, ribcage
How many appendicular bones in the body?
126
Examples of appendicular bones
shoulders, arms, hips, legs
Difference between male and female pelvis
female= smoother, lighter, iliac is more flared, larger pelvic inlet and outlet, larger pubic angle, less curvature of sacrum/coccyx
two layers of the integumentary system (cutaneous system)
epidermis and dermis
Epidermis (qualities)
outermost layer, keratinized, stratified squamous ET
Dermis (qualities)
Innermost layer, ET, CT, MT, NT
Subcutaneous layer (type of tissue)
adipose
thin epidermis (qualities)
covers most of your body, 4 strata, .1 mm thick
thick epidermis (qualities)
palms of your hands and soles of your feet, 5 strata, .5 mm thick
Name the layers of the epidermis (5)
stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale
Stratum corneum (qualities)
dead epithelium filled with keratin, 15-30 layers of densely packed keratinocytes, tough and water-resistant, shed or washed away
Stratum lucidum (qualities)
translucent, only in soles and palms, dehydrating and dead
Stratum granulosum (qualities)
3-5 layers of flattened granular cells filled with keratin, proteins bind keratin in bundles, release lipid mixture to coat membrane
Stratum spinosum (qualities)
many layers of rounded cells with large nuclei (desmosomes), making keratin filaments and flattening, dendritic cells (white blood cells)
Stratum basale (qualities)
single row of mitosing cuboidal cells and melanocytes, along with Merkel cells/tactile discs
Function of epidermis (6)
excretes, produces, maintains body temp, detects, stores, protects
Epidermis excretion (4)
water, urea, salt, other wastes
Epidermis produces (3)
melanin, vitamin D, keratin
How does the epidermis maintain body temp?
evaporative cooling and insulation
Epidermis detection (4)
touch, pressure, temp, pain
Epidermis storage (1)
fats
Epidermis protection (3)
Moisture loss, injury, against microorganisms and chemicals
What is the purpose of epidermal ridges and dermal papilla? (3)
resists slippage between both layers, finger prints increase friction, and allows for increase sensitivity for touch receptors
Pigments in the epidermis (3)
hemoglobin, carotene, and melanin
Epidermis hemoglobin (purpose)
blood supply, carries oxygen
Epidermis carotene (purpose)
diet