week 2- levels of evidence, research designs

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25 Terms

1

systematic

research design that presents the strongest level of evidence for all types of questions

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2

RCTs (randomized control trials)

research design with the 2nd-best level of evidence for all types of questions

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3

longitudinal

kind of study that follows subjects through time, measuring data at prescribed intervals

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4

cross-sectional

kind of study that gives a snapshot of a population at one point in time

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5

mechanistic

what kind of study is animal and in-vitro?

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6

case report

study that describes the experience and/or treatment of an individual

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7

case series

study with 1<x<20 individuals, composing of their case studies

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8

case control

kind of study where people with a condition are compared to similar people without the condition

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9

cohort

study that monitors individuals prospectively or retrospectively to assess the development of a disease or other outcome

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10

prospective cohort study

best kind of study to assess prognosis and etiology

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11

randomized control trial

study where a group of similar people are randomly assigned to different treatment groups in order to test the effect of an intervention

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12

meta-analysis

name for when data of many studies in a systematic review are compiled and analyzed as one big study

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13

clinical practice guidelines (CPG)

systematically developed summary of research that includes recommendations for clinical practice

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14

3

what level of evidence is a cohort study?

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15

4

what level of evidence is a case report/case series/case-control study?

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16

5

what level of evidence is mechanistic, like expert opinion or animal studies?

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17

experimental, quasi-experimental, non-experimental

3 kinds of research designs

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18

experimental

kind of design with purposeful manipulation of some variables

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19

quasi-experimental

kind of design with purposeful manipulation of groups of subjects, lacking a control group and/or randomization

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20

non-experimental

kind of research design with no purposeful manipulation of subjects and pre-determine groups

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21

institutional review board

what does IRB stand for?

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22

more than minimal risk to participants, involves sensitive topic, involves minors

when is IRB approval required?

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23

non-invasive research that involves questionnaires or surveys

when would expedited IRB review be reasonable to request?

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24

poses little risk to participants, doesn’t involve a sensitive topic, doesn’t involve minors

when is a study IRB-exempt?

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25

educational settings among normal curriculum

exception to a study not being exempt from the IRB due to involvement of minors

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