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Major Hypothalamus-Pituitary-Regular Hormones and other hormones
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Vasopressin
-peptide hormone
-made by hypothalamus
-secreted by posterior pituitary gland
-tells nephrons in kidneys to reabsorb water
-causes arterioles to vasoconstrict
Oxytocin
-peptide hormone
-made by hypothalamus
-secreted by posterior pituitary gland
-promotes contraction of uterus during childbirth
-causes ejection of milk from mammary glands
Thyrotropin-Releasing Hormone (TRH)
-peptide hormone
-made & secreted by hypothalamus
-stimulates release of TSH & PRL
Corticotropin-releasing hormone (CRH)
-peptide hormone
-stimulates release of ACTH
-made & secreted by hypothalamus
Gonadotropin-releasing hormone (GnRH)
-peptide hormone
-stimulates release of FSH & LH (gonadotropins)
-made & secreted by hypothalamus
Growth hormone-releasing hormone (GHRH)
-peptide hormone
-stimulates release of GH
-made & secreted by hypothalamus
Somatostatin (growth hormone-inhibiting hormone; GHIH)
-peptide hormone
-inhibits release of GH & TSH
-made & secreted by hypothalamus
Prolactin-releasing peptide (PrRP)
-peptide hormone
-stimulates release of PRL
-made & secreted by hypothalamus
Dopamine (prolactin-inhibiting hormone; PIH)
-Catecholamine hormone
-inhibits release of PRL
-made & secreted by hypothalamus
Growth Hormone (GH, somatotropin)
-peptide hormone
-made & secreted by anterior pituitary
-secreted by somatotropes
-regulates body growth and exerts metabolic effects
-stimulates release of insulin-like growth factor 1 (IGF-1)
-uses JAK/STAT pathway
Thyroid-Stimulating Hormone (TSH, thyrotropin)
-peptide hormone
-made & secreted by anterior pituitary
-secreted by thyrotropes
-stimulates secretion of thyroid hormone and growth of thyroid gland
-uses cAMP
Adrenocorticotropic hormone (ACTH, adrenocorticotropin)
-peptide hormone
-made & secreted by anterior pituitary
-secreted by Corticotropes
-stimulates cortisol and androgen secretion and promotes growth of adrenal cortex
-precursor -- pro-opiomelanocortin (POMC)
-uses cAMP pathway
Follicle-Stimulating Hormone (FSH)
-peptide hormone
-made & secreted by anterior pituitary
-secreted by Gonadotropes
-helps regulate gamete production in both sexes
-in females it stimulates grwoth & develop of ovarian follicles
-needed for sperm production
-uses cAMP pathway
Luteinizing Hormone (LH)
-peptide hormone
-made & secreted by anterior pituitary
-secreted by Gonadotropes
-helps control sex hormone secretion in both sexes
-regulates ovarian secretion of estrogen and progesterone
-stimulates testes to secrete testosterone
-responsible for ovulation and luteinization
-uses cAMP pathway
Prolactin (PRL)
-peptide hormone
-made & secreted by anterior pituitary
-secreted by Lactotropes
-enhances breast development and lactation
-uses JAK/STAT pathway
Insulin
-peptide hormone
-stimulated by high glucose
-secreted by beta cells
-lowers blood glucose
-stores energy
-helps cells uptake glucose
Glucagon
-peptide hormone
-stimulated by low blood glucose
-secreted by alpha cells in the pancreas
-raises blood glucose and fatty acids levels in the liver
Amylin
-peptide hormone
-stimulated by large food intake
-secreted by beta cells in pancreas