Necrosis vs Apoptosis

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12 Terms

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Necrosis cell size

Enlargened (swollen)

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Apoptosis cell size

Reduced (shrinkage)

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Apoptosis nucleus

Fragmented into nucleosome sized pieces

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Necrosis nucleus

Pyknosis

Karyorrhexis

Karyolysis

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Necrosis plasma membrane

Ruptured

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Apoptosis plasma membrane

Intact

Altered structure (especially orientation of lipids)

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Necrosis cellular contents

Enzymatic digestion

May leak out of cell

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Apoptosis cellular components

Intact

May be released into apoptotic bodies

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Necrosis adjacent inflammation

Frequent

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Apoptosis adjacent inflammation

No

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Necrosis physiologic or pathologic

Pathologic

Culmination of irreversible cell injury

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Apoptosis physiologic or pathologic

Physiologic

Eliminating unwanted cells may be pathologic after cell injury (especially dna damage)