Top Drugs 400

Acetylcysteine (Acetadote)

I: Acetaminophen overdose

D: 300mg/kg total dose administered as a 21-hour IV infusion regimen consisting of 3 doses. First load over 1 hour, second over 4 hours, third over 16 hours.

Acyclovir (Zovirax)

I: Antiviral

D: 200mg orally every 4 hours for 5 doses/day for 10 days

Albuterol sodium (Proventil, Ventolin, Proair)

I: Asthma, COPD, Bronchospasm

D: 1-2 inhalations (90mcg HFA) every 4-6 hours

Alendronate (Fosamax)

I: Osteoporosis

D: 10mg orally once daily OR 70mg once weekly

Allopurinol (Zyloprim)

I: Gout

D: 200-300mg by mouth once a day

Alprazolam (Xanax, Xanax XR)

I: Anxiety

D: 0.25-0.5mg by mouth 3 times a day prn

C: II

Alteplase (Activase)

I: Acute ischemic stroke

D: Load with 0.09mg/kg IV over 1 minute, followed by 0.81mg/kg continuous infusion over 60 minutes (MAX 90mg)

Amiodarone (Cordarone, Pacerone, Nexterone)

I: Arrhythmia

D: 200-400mg by mouth once a day

Amitriptyline (Elavil)

I: Depression

D: 10-100mg by mouth in divided doses or at bedtime

Amlodipine (Norvasc)

I: Hypertension

D: 5mg by mouth once daily

Amoxicillin (Amoxil, Moxatag, Trimox)

I: Bacterial infection

D: 250-500mg by mouth every 8 hours OR 500-875mg every 12 hours

Amoxicillin/Clavulanate (Augmentin, Augmentin XR)

I: Bacterial infection

D: 500/125mg by mouth every 8 hours OR 875/125mg every 12 hours

Amphetamine/Dextroamphetamine salts (Adderall, Adderall XR)

I: ADHD

D: 5-20mg (XR) by mouth once a day

C: II

Ampicillin/Sulbactam (Unasyn)

I: Bacterial infection

D: 1.5g IV infusion every 6 hours (dose is combination of ampicillin & sulbactam)

Anastrozole (Amrimidex)

I: Breast cancer

D: 1mg by mouth once a daily

Apixaban (Eliquis)

I: Anticoagulantion

D: 5mg by mouth two times a day

Aripiprazole (Abilify, Abilify maintena)

I: Schizophrenia

D: 10mg by mouth once a day

Atenolol (Tenormin)

I: Hypertension

D: 50mg by mouth once a day

Atomoxetine (Strattera)

I: ADHD

D: 80mg by mouth once a day OR 40mg by mouth two times a day

Atorvastatin (Lipitor)

I: Dyslipidemia

D: 10mg by mouth once a day

Azelastine (Astelin, Astepro)

I: Rhinitis

D: 2 sprays per nostril twice a day

Azithromycin (Zithromax, Zmax)

I: Bacterial infection

D: 500mg by mouth on day 1, 250mg by mouth on days 2-5

Baclofen (Lioresal)

I: Musculoskeletal pain/spasm

D: 10mg by mouth three times a day prn

Benzonatate (Tessalon)

I: Antitussive (cough)

D: 100mg three times daily prn

Bimatoprost opthalmic (Lumigan, Latisse)

I: Glaucoma

D: 1 drop into affected eye(s) once daily in the evening

Brimonidine Tartrate opthalmic (Alphagan-P)

I: Glaucoma

D: 1 drop into affected eye(s) three times daily 8 hours apart

Budesonide (Pulmicort)

I: Asthma

D: 360mcg inhaled two times a day

Budesonide/Formoterol (Symbicort)

I: Asthma, COPD

D: 2 inhalations of 160mcg/4.5mcg MDI two times a day

Bupropion (Wellbutrin, SR, XL, Zyban)

I: Depression, smoking cessation

D: 150mg ER once a day

Buspirone (Buspar)

I: Anxiety

D: 5mg by mouth three times a day prn

Butalbital, Acetaminophen, & caffeine (Fioricet)

I: Tension headache

D: Capsule- 50mg/300mg/40mg. Tablet- 50mg/325mg/40mg. Dose- 1-2 capsules/tablets every 4 hours prn not to exceed 6 per day

Carbamazepine (Tegretol, XR, Carbatrol ER, Equerto ER)

I: Seizures

D: 400mg by mouth three times

Carvidopa/Levodopa (Sinemet, CR, Rytary)

I: Parkinson’s disease

D: 25/100mg by mouth three times

Cariprazine (Vraylar)

I: Antipsychotic

D: 1.5mg by mouth once daily

Carisoprodol (Soma)

I: Pain relief of musculoskeletal conditions

D: 250-350mg by mouth three times per day & at bedtime

C: IV

Carvedilol (Coreg, CR)

I: Hypertension

D: 6.25mg by mouth two times a day

Cefazolin (Ancef)

I: Bacterial infection

D: 1-2g IV every 8 hours

Cefidinir (Omnicef)

I: Bacterial infection

D: 600mg by mouth daily in 1 or 2 divided doses

Cefepime (Maxipime)

I: Bacterial infection

D: 1-2g IV every 8 hours

Ceftriaxone (Rocephin)

I: Bacterial infection

D: 1-2g IV/IM every 24 hours

Celecoxib (Celebrex)

I: Pain, Osteoarthritis

D: 200mg by mouth daily

Cephalexin (Keflex)

I: Bacterial infection

D: 500 by mouth every 12 hours

Chlorhexidine (Peridex, Periogard)

I: Gingivitis

D: Swish oral rinse for 30 seconds two times a day

Chlorthalidone (Hygroton)

I: Edema

D: 12.5mg by mouth once a day

Ciprofloxacin (Cipro, XR)

I: Bacterial infection

D: 500mg by mouth two times a day

Cisatracurium (Nimbex)

I: Paralytic

D: Initial IV bolus of 0.1-0.2mg/kg. Continuous fusion of 1-3mcg/kg/min

Citalopram (Celexa)

I: Depression

D: 20mg by mouth once a day

Clindamycin (Cleocin)

I: Bacterial infection

D: 300mg by mouth every 6 hours

Clonazepam (Klonopin)

I: Panic disorder

D: 0.25mg by mouth two times a day

C: IV

Clonidine (Catapres, TTS, Nexiclon XR)

I: Hypertension

D: 0.1mg by mouth two times a day

Clonidine ER (Kapvay)

I: ADHD

D: 0.1mg by mouth two times a day

Clopidogrel (Plavix)

I: Reduction of atherosclerotic events

D: 75mg by mouth once a day

Clozapine (Clozaril, Versacloz)

I: Schizophrenia

D: Initial 12.5mg by mouth 1-2 times a day (MAX 900mg/day)

Codeine phosphate w/ Guaifenesin (Mytussin AC, Robitussin AC)

I: Antitussive

D: 5-10mL by mouth every 4-6 hours not to exceed 60mL per 24 hours

C: V

Colestipol Hydrochloride (Colestid)

I: Dyslipidemia

D: Tablets- 2g by mouth 1-2 times per day. Granules- 5g by mouth 1-2 times per day

Cyanocobalamin Vitamin B-12 (Nascobal)

I: Vitamin B12 deficiency

D: 1000mcg intramuscular or subcutaneously once per month

Cyclobenzaprine (Amrix, Flexeril, Fexmid)

I: Musculoskeletal pain/spasm

D: 10mg by mouth three times a day

Cyclosporin Emulsion ophthalmic (Restasis)

I: Keratoconjunctivitis sicca (dry eye syndrome)

D: Instill 1 drop in each eye twice daily at 12 hours intervals

Dapagliflozin (Farxiga)

I: Diabetes

D: 5-10mg by mouth in the morning

Desvenlafaxine (Pristiq)

I: Depression

D: 50mg by mouth once a day

Dexmedetomidine (Precedex)

I: Sedetion

D: 0.2-1.5mcg/kg/hour

Diazepam (Valium)

I: Anxiety

D: 2mg by mouth every 4 hours prn

C: IV

Diclofenac (Voltaren, XR)

I: Pain

D: 50mg by mouth three times a day

Diclofenac topical (Voltaren gel)

I: Osteoarthritis

D: Apply 2g to affected area of upper extremity or 4g to lower extremity up to 4 times a day, MAX total body dose 32g/day

Dicyclomine (Bentyl)

I: IBS

D: 20mg by mouth up to 4 times a day 30 min before meals

Digoxin (Lanoxin, Digitek)

I: Heart failure, atrial fibrillation

D: 0.125-0.25mg by mouth once a day (dose individualized based on serum levels)

Diltiazem (Cardizem, CD, Cartia, Dilacor, Dilt-XR, Tiazac

I: Hypertension

D: 240mg by mouth divided 1-2 times daily

Dipyridamole & Aspirin (Aggrenox)

I: Ischemic stroke prevention

D: 200mg/25mg capsule by mouth twice daily

Divalproex sodium (Depakote, ER)

I: Bipolar disorder, seizures

D: 250mg by mouth three times a day

Dobutamine (Dobutrex)

I: Heart failure

D: Initial dose- 2-5mcg/kg/min IV titrated to clinical effect

Dofetilide (Tikosyn)

I: Atrial fibrillation (flutter)

D: 500mg by mouth twice daily

Donepezil (Aricept)

I: Alzheimer’s disease

D: 5-10mg by mouth at bedtime

Dopamine (Intropin)

I: Shock

D: 1-20 mcg/kg/min IV titrated to clinical effect

Doxycycline (Vibramycin, Doryx)

I: Bacterial infection

D: 100mg by mouth every 12 hours

Duloxetine (Cymbalta)

I: Depression

D: 40-60mg by mouth 1 time a day

Empagliflozin (Jardiance)

I: Diabetes

D: 10-25mg by mouth daily in the morning

Enoxaparin (Lovenox)

I: Anticoagulation

D: 1mg/kg subcutaneous every 12 hours or 1.5mg/kg once daily

Ephedrine (Akovaz, Emerphed)

I: Hypotension caused by anesthesia

D: IV bolus- 5-10mg once, may repeat dose (max 50mg total)

Epinephrine (EpiPen, Auvi-Q, Adrenalin)

I: Anaphylaxis

D: Inject 0.3mg IM, may repeat dose if patient not responding

Epoprostenol (Veletri, Flolan)

I: Pulmonary hypertension

D: Initial 2 ng/kg/min IV, titrated up in increments of 1-2 ng/kg/min every 15 minutes. Usual dose is 25-40 ng/kg/min

Escitalopram (Lexapro)

I: Depression

D: 10mg by mouth once daily

Esomeprazole (Nexium)

I: GERD

D: 20mg by mouth once daily

Estradiol oral (Estrace)

I: Menopausal vasomotor symptoms

D: 0.5mg by mouth once daily

Estradiol topical (Vivelle-Dot, Alora, Climara)

I: Menopausal vasomotor symptoms

D: Product dependent- patches are typically applied 1-2 times per week per product labeling

Estradiol vaginal (Femring, Estring, Vagifem, Divigel)

I: Menopausal vasomotor symptoms

D: Product dependent

Eszopiclone (Lunesta)

I: Insomnia

D: 2mg by mouth at bedtime

C: IV

Evolcumab (Repatha)

I: Dyslipidemia

D: 140mg subcutaneously every 2 weeks or 420mg subcutaneously once per month

Ezetimibe (Zetia)

I: Dyslipidemia

D: 10mg by mouth once daily

Famotidine (Pepcid)

I: GERD

D: 20mg by mouth 2 times a day

Fenofibrate (Lipofen, Tricor)

I: Dyslipidemia

D: 145mg by mouth once daily

Fentanyl transdermal patch (Duragesic)

I: Chronic pain

D: 1 patch applied topically every 72 hours, remove & replace after

C: II

Finasteride (Proscar)

I: BPH

D: 5mg by mouth once daily

Fluconazole (Diflucan)

I: Candida infection

D: 150mg by mouth as a single dose or may require daily treatment

Fluoxetine (Prozac, Sarafem*)

I: Depression, premenstrual dysphoria disorder*

D: 20mg by mouth once daily

Fluticasone furoate/Vilanterol (Breo Ellipta)

I: COPD

D: 1 inhalation of 100/25mcg daily

Fluticasone furoate/Umeclidinium bromide/Vilanterol (Trelegy Ellipta)

I: COPD

D: 1 inhalation of 100/62.5/25mcg daily

Fluticasone propionate nasal (Flonase)

I: Allergic rhinitis

D: 2 sprays in each nostril once daily

Fluticasone/Salmeterol (Advair)

I: Asthma

D: 1 diskus inhalation or 2 HFA inhalations 2 times daily

Folic acid

I: Folic acid deficiency

D: Up to 1mg by mouth daily

Fremanezumab-vfrm (Ajovy)

I: Migraine

D: 225 subcutaneously monthly or 675mg subcutaneously every 3 months