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Spinal Cord
-extends from the brain at foramen magnum down to the second lumbar vertebra.
-Terminates in the conus medullaris
-shorter than vertebral column
Cauda equina
group of nerves leaves the inferior spinal cord and extends downward. Resembles a horses tail.
Cervical enlargement
has nerve fibers that supply the upper limbs
lumbosacral enlargement
has nerve fibers supplying the lower limbs
Spinal cord
larger in diameter at its superior end and gradually decreases in diameter toward its inferior end
31 pairs of spinal nerves
-8 cervical
-12 thoracic
-5 lumbar
-5 sacral
-1 coccygeal
spinal nerves
exit the vertebral column through intervertebral and sacral foramina and connect with various body regions
Spinal cord surroundings
dura mater, arachnoid, and pia mater
dura mater around the spinal cord
is separated from the periosteum of the vertebral canal by the epidural space
epidural space around the spinal cord
is a true space with spinal nerve roots, blood vessels, areolar connective tissue, and adipose tissue
subarachnoid space
between arachnoid mater and pia mater; contains weblike strands of the arachnoid mater, blood vessels, and cerebrospinal fluid.
epidural anesthesia
often administered in women during childbirth by injecting anesthetics into the epidural space of the spinal cord
anterior media fissure and posterior median sulcus
two deep grooves; anterior fissure is deeper and wider
Gray matter
cell bodies of interneurons and motor neurons in addition to dendrites and unmyelinated axons; in transverse section, looks like "H" w/ anterior posterior, & lateral limb (horns)
White matter
surrounds the gray matter and is subdivided into anterior, posterior, and lateral white columns (funiculi).
Pathways
Each white matter column consists of a large bundle of myelinated axons divided into tracts or fascicles.
Gray and white commissures
-connect the two halves of the spinal cord
-contain axons that cross from one side of the spinal cord to the other
Central canal
located in the center of the gray commissure; helps circulate CSF (cerebrospinal fluid)
Ventral roots
axons of motor neurons which innervate muscles and glands
dorsal roots
the axons of these pseudo-unipolar sensory neurons extends from various parts of the body and pass through spinal nerves to…
dorsal root ganglion OR spinal ganglion
sensory neuron cell bodies are contained within here
4 main nerve plexuses
1. cervical plexus
2. brachial plexus
3. lumbar plexus
4. sacral plexus
cervical plexus
supplies nerves to the posterior head and neck, as well as to the diaphragm
brachial plexus
supplies nerves to the arm
lumbar plexus
supplies nerves to the anterior leg
sacral plexus
supplies nerves to the posterior leg
Spinal cord function
function to transmit messages to and from the brain (white matter) and to serve as a reflex center (gray matter)
reflex
automatic response to a stimulus, occurs w/o conscious though; homeostatic
Autonomic reflexes
responsible for maintaining relatively constant blood pressure, blood CO2 levels, and water intake
Somatic reflexes
remove the body from painful stimuli that cause tissue damage or keep body from suddenly falling or moving b/c of external forces
reflex arc
neural pathway that controls a reflex; basic functional unit of the nervous system that is capable of receiving a stimulus and producing a response
components of a reflex arc
1. receptor
2. sensory neuron
3. integration center
4. motor neuron
5. effector
receptor
site of stimulus
sensory neuron
transmits afferent info to the CNS
integration center
1 or more interneurons
motor neuron
transmits efferent signals to effector
effector
muscle or gland
somatic
reflexes involving skeletal muscles and somatic motor neurons
autonomic
reflexes controlled by autonomic neurons are
spinal reflexes
integrated within the spinal cord while cranial reflexes are integrated in the brain
stretch reflex
simplest reflex; contraction of muscles in response to stretching of that same muscle
Ex: knee-jerk reflex (patellar reflex)
golgi tendon reflex
prevents contracting muscles from applying excessive tension to tendons. The sensory receptors for this reflex are called golgi tendon organs; located at muscle-tendon junction.
withdrawal reflex OR flexor reflex
removing a limb or another body part from a painful stimulus
Nerve structure
organized by layers of connective tissue on the outside, around each fascicle, and surrounding individual nerve fibers.
Spina bifida
-condition that affects spine and usually apparent in birth; type of neural tube defect (NTD).
-Can occur anywhere along the spine if the neural tube does not close all the way
spinal transection
tear w/ spinal cord after a traumatic injury
spinal shock
physiologic or anatomic transection of the spinal cord that results in temporary loss or depression of all or most spinal reflex activity below the level of the injury
phantom limb pain
pain felt in arm or leg that has been amputated; although limb is gone, nerve ending at the site of amputation continue to send pain signals to the brain that make the brain think the limb is still there
Phrenic (C3-C5)
diaphragm
Radial (C5-C8, T1)
skin and muscles of posterior arm, forearm, and hand; thumb and first 2 fingers
Median (C5-C8, T1)
skin and muscles of anterior arm, forearm, and hand
Ulnar (C8, T1)
skin and muscles of medial arm , forearm, and hand; little finger and ring finger
Intercostal (T2-T12)
intercostal muscles, abdominal muscles; skin or trunk
femoral (L2-L4)
skin and muscles of anterior thigh, medial leg, and foot
Sciatic (L4-S3)
skin and muscles of posterior thigh, leg and foot