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Last updated 1:20 AM on 7/8/26
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Q: If an enzyme lowers activation energy, does it make an endergonic reaction exergonic?

A: No. It speeds the reaction but does not change ΔG.

2
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Q: Is ATP energy stored in the phosphate bonds or released because the products after hydrolysis are more stable?

A: The latter. ATP hydrolysis is favorable because the products (ADP + Pi) have lower free energy and greater stability than ATP. A common shorthand is that ATP stores usable chemical potential in its phosphoanhydride bonds, but the energy released comes from the overall change in bonding and stabilization of the products.

3
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Q: Can a reaction be spontaneous and still require activation energy?

A: Yes.

4
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Q: Does equilibrium mean reactions stop?

A: No. Forward and reverse reactions continue at equal rates.