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Q: If an enzyme lowers activation energy, does it make an endergonic reaction exergonic?
A: No. It speeds the reaction but does not change ΔG.
Q: Is ATP energy stored in the phosphate bonds or released because the products after hydrolysis are more stable?
A: The latter. ATP hydrolysis is favorable because the products (ADP + Pi) have lower free energy and greater stability than ATP. A common shorthand is that ATP stores usable chemical potential in its phosphoanhydride bonds, but the energy released comes from the overall change in bonding and stabilization of the products.
Q: Can a reaction be spontaneous and still require activation energy?
A: Yes.
Q: Does equilibrium mean reactions stop?
A: No. Forward and reverse reactions continue at equal rates.