Pharm Test 1

Codeine Sulfate: class, use, side effects

Class & Use: Opioid analgesic (pain reliever & antitussive) used for mild to moderate pain and cough suppression.

Side effects: resp. depression, drowsiness, N/V, constipation, hypotension

Hydrocodone/APAP (Norco): class, use, side effects

Opioid analgesic used to treat moderate to severe pain.

Side effects: resp. depression, drowsiness, N/V, constipation

Hydromorphone (Dilaudid): class, use, side effects

Opioid analgesic used for moderate to severe pain management.

Side effects: resp depression, sedation, N/V, constipation, hypotension

Morphine Sulfate: class, use, side effects

Opioid analgesic used for severe pain management, especially in cancer and post-op patients.

Side effects: resp depression, hypotension, constipation, sedation

Naloxone (Narcan): class, use, side effects

Opioid analgesic antidote used to reverse opioid overdose.

Side effects: withdrawal symptoms (pain, tachycardia, HTN), N/V

Aspirin (Ecotrin): class, use, side effects

Salicylate used for pain, fever, inflammation, and prevention of cardiovascular events.

Side effects: GI bleeding, Reye’s syndrome, bleeding risk

Celecoxib: class, use, side effects

COX-2 inhibitor NSAID used for pain, osteoarthritis, and rheumatoid arthritis.

Side effects: GI bleeding, cardiovascular events, renal impairment

Ibuprofen (Advil, Motrin): class, use, side effects

NSAID used for pain, inflammation, and fever.

Side effects: Gi bleeding, renal impairment, increased cardiovascular risk

Ampicillin/Sulbactam: class, use, side effects

Penicillin-beta-lactamase inhibitor antibiotic used for bacterial infections (skin, respiratory, & intra-abdominal)

Side effects: allergic reactions, diarrhea, superinfection, nausea

Cefazolin: class, use, side effects

Cephalosporin antibiotic used for bacterial infections and surgical prophylaxis.

Side effects: allergic reactions, diarrhea, superinfection

Levofloxacin: class, use, side effects

Fluoroquinolone/Quinolone antibiotic used for various bacterial infections (respiratory, UTI, skin)

Side effects: tendon rupture, QT prolongation, C. diff infection

Rifampin: class, use, side effects

Rifamycin antibiotic used for treating TB & HIV.

Side effects: hepatotoxicity, red/orange body fluids, GI upset

Sertraline (Zoloft): class, use, side effects

SSRI antidepressant used for depression, anxiety, OCD, PTSD.

Side effects: sexual dysfunction, weight changes, serotonin syndrome, insomnia

Bupropion (Wellbutrin): class, use, side effects

Atypical antidepressant used for depression and smoking cessation.

Side effects: seizures (especially in high doses), insomnia, dry mouth, mania

Hydroxyzine (Vistaril): class, use, side effects

Antihistamine used for anxiety, nausea, itching, and sleep problems.

Side effects: drowsiness, dry mouth, dizziness

Diazepam (Valium): class, use, side effects

Benzodiazepine used for anxiety, muscle spasms, seizures, and alcohol withdrawal.

Side effects: sedation, resp depression, dizziness, dependence, severe liver disease, hypotension

Allopurinol: class, use, side effects

Xanthine oxidase inhibitor used as an anti-gout agent to prevent gout attacks.

Side effects: rash (including Stevens-Johnson syndrome), nausea, kidney stones, liver toxicity, diarrhea

Colchicine: class, use, side effects

Anti-gout agent used for gout flares and prevention.

Side effects: diarrhea, nausea, myelosuppression (bone marrow suppression), abdominal cramping, muscle pain, and neuropathy

Fexofenadine (Allegra): class, use, side effects

Antihistamine used for seasonal allergies and allergic conditions.

Side effects: drowsiness, dry mouth, headache, dizziness, swelling

Atenolol: class, use, side effects

Beta-blocker used to treat hypertension, angina, and post-MI management.

Side effects: bradycardia, hypotension, fatigue, dizziness

Timolol: class, use, side effects

Beta-blocker used as an anti-glaucoma agent.

Side effects: eye irritation, bradycardia, hypotension

Amlodipine: class, use, side effects

Calcium channel blocker used for hypertension and angina.

Side effects: edema, dizziness, hypotension, flushing, arrythmia

Nevirapine: class, use, side effects

NNRTI antiretroviral used for HIV treatment.

Side effects: fatigue, nausea, hepatotoxicity, rash (Stevens-Johnson syndrome), immune reconstitution syndrome

Zidovudine: class, use, side effects

NRTI antiretroviral used for HIV treatment and prevention of maternal-fetal transmission.

Side effects: bone marrow suppression (anemia, neutropenia), lactic acidosis, hepatomegaly, myopathy

Alprazolam (Xanax): class, use, side effects

Benzodiazepine used to treat anxiety and panic disorders.

Side effects: drowsiness, dizziness, dependence, resp depression

Montelukast (Singulair): class, use, side effects

Leukotriene receptor antagonist used for asthma maintenance.

Side effects: mood changes, (depression, suicidal thoughts), H/A, GI upset, anaphalaxis

Dexamethasone (Decadron): class, use, side effects

Corticosteroid used as an anti-inflammatory and immunosuppressant.

Side effects: osteoporosis, hyperglycemia, weight gain, mood changes, immunosuppression, GI ulcers, insomnia

Methylprednisolone (Medrol): class, use, side effects

Corticosteroid used for inflammatory and autoimmune conditions.

Side effects: hyperglycemia, osteoporosis, fluid retention, mood changes, immunosuppression

Hydrocortisone: class, use, side effects

Corticosteroid used to treat adrenal insufficiency, inflammation, and overactive immune response

Side effects: hyperglycemia, osteoporosis, Cushing’s syndrome, mood changes

Ferrous sulfate: class, use, side effects

Iron supplement used to treat iron deficiency anemia.

Side effects: constipation, black & tarry stools, GI upset

Famotidine (Pepcid): class, use, side effects

H2 receptor antagonist used as an anti-ulcer agent.

Side effects: H/A, dizziness, constipation, diarrhea, confusion (elderly pts)

Docusate Sodium (Colace): class, use, side effects

Stool softener used for constipation.

Side effects: abdominal cramping, diarrhea

Lactulose (Kristalose): class, use, side effects

Osmotic laxative used for constipation and hepatic encephalopathy.

Side effects: diarrhea, electrolyte imbalance, bloating

Filgrastim: class, use, side effects

Colony-stimulating factor used to increase WBCs in neutropenic patients.

Side effects: bone pain, leukocytosis (excessive WBC production), splenomegaly, fever, fatigue, nausea, H/A, injection site reactions, splenic rupture, allergic reactions, ARDS

Epoetin: class, use, side effects

Erythropoiesis-stimulating agent used to treat anemia.

Side effects: clot risk, seizures, HTN, H/A fever, pure red cell aplasia, joint pain, thromboembolic events

Acetylcysteine (Mucomyst): class, use, side effects

Mucolytic agent used for acetaminophen overdose and to loosen mucus.

Side effects: N/V, bronchospasm, rash, dizziness, unpleasant sulfur-like odor, hypotension

Clopidogrel: class, use, side effects

Antiplatelet agent used to prevent blood clots in stroke/MI patients.

Side effects: bleeding, bruising, GI upset, TTP, sever hemorrhage

Diphenoxylate/Atropine: class, use, side effects

Opioid antidiarrheal used to slow intestinal motility.

Side effects: drowsiness, dry mouth, constipation, dependence, toxic megacolon (if used in infectious diarrhea), CNS depression, anticholinergic toxicity

Infliximab: class, use, side effects

Monoclonal antibody used in autoimmune diseases.

Side effects: infusion reactions (fever, chills), H/A, nausea, increased infection risk, TB reactivation, hepatotoxicity, lymphoma, heart failure

Alendronate: class, use, side effects

Bisphosphonate used for osteoporosis and Paget’s disease (prevents bone loss).

Side effects: esophagitis, GI upset, hypocalcemia, musculoskeletal pain: class, use, side effects

ANALGESICS

opioids: codeine sulfate, hydrocodone/APAP, hydromorphone, morphine sulfate, naloxone

NSAIDS: aspirin, celecoxib, ibuprofen

ANTIBIOTICS

ampicillin/sulbactam, cefazolin, levofloxacin, rifampin

ANTIDEPRESSANTS

sertraline (SSRI), bupropion (NDRI)

ANTIEMETIC

hydroxyzine

ANTIEPILEPTIC

diazepam

ANTIGOUT AGENTS

allopurinol, colchicine

ANTIHISTAMINES

hydroxyzine, fexofenadine

ANTIHYPERTENSIVES

beta blocker: atenolol, timolol

calcium channel blocker: amlodipine

ANTIRETROVIRALS (HIV/AIDS)

nevirapine, zidovudine

ANXIOLYTICS

benzodiazepines: alprazolam, diazepam

BRONCHODILATOR (LRA)

montelukast

CORTICOSTEROIDS

dexamethasone, methylprednisolone, hydrocortisone

ELECTROLYTE SUPPLEMENT

ferrous sulfate

GI AGENTS

H2 blocker: famotidine

laxatives: docusate sodium (stool softener), lactulose (osmotic laxative)

HEMATOPOIETIC AGENTS

filgrastim, epoetin

MUCOLYTIC

acetylcysteine

ANTIPLATELET AGENTS

clopidogrel, aspirin

ANTIDIARRHEALS

diphenoxylate/atropine

IMMUNOSUPPRESSANTS

infliximab, dexamethasone, methylprednisolone

BONE RESORPTION INHIBITOR

alendronate

codeine sulfate: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Ed: Avoid alcohol. Take w/ food if GI upset occurs. Monitor respiratory status, BP, and bowel function

Labs to Monitor: N/A

Impact on Other Diseases: can exacerbate respiratory issue (COPD & asthma pts) and may worsen GI motility disorders

hydrocodone/APAP: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Ed: Monitor RR, caution with CNS depressants. Take with food if GI upset occurs.

Labs to Monitor: Liver function (APAP component), renal function

Impact on Other Diseases: Caution in pts w/ a h/o substance abuse, resp. disorders, or liver disease

hydromorphone: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor resp. status. Avoid alcohol and CNS depressants. Use stool softeners to prevent constipation.

Labs to Monitor: N/A

Impact on Other Diseases: can exacerbate resp. depression in pts w/ COPD or asthma

morphine sulfate: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor RR and BP. Educate about addiction risk. Encourage fluids and fiber intake.

Labs to Monitor: N/A

Impact on Other Diseases: can exacerbate resp. conditions and worsen GI motility disorders

naloxone: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor RR and BP. Reassess for resp. depression after administration (short half-life).

Labs to Monitor: N/A

Impact on Other Diseases: N/A

aspirin: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Take with food to reduce GI irritation. Monitor for signs of bleeding. Avoid in children with viral infections

Labs to Monitor: Platelet, Hgb, & Hct count, liver function tests (ALT, AST), kidney enzymes (BUN, creatinine)

Impact on Other Diseases: can increase the risk of GI bleeding and worsen renal function in pts w/ kidney disease

celecoxib: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Take with food. Avoid with other NSAIDs. Caution in pt w/ HTN

Labs to Monitor: Renal function, liver enzymes

Impact on Other Diseases: can increase the risk of heart attack, stroke, and GI bleeding. It can also worsen renal function in pts w/ kidney issues

ibuprofen: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Take with food. Avoid with anticoagulants and prolonged use

Labs to Monitor: Renal function, liver function tests

Impact on Other Diseases: Can worsen kidney function and increase the risk of cardiovascular events, particularly in long-term use

Ampicillin/Sulbactam: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Assess for penicillin allergy. Monitor for signs of superinfection (e.g., oral thrush, unusual vaginal discharge)

Labs to Monitor: CBC, renal function, liver function tests

Impact on Other Diseases: can cause an overgrowth of non-susceptible organisms (e.g., C. difficile), leading to secondary infections

cefazolin: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Screen for penicillin allergy. Monitor for C. difficile infection

Labs to Monitor: Renal function, WBC count, liver enzymes

Impact on Other Diseases: can cause or worsen GI infections (e.g., C. difficile) and may increase the risk of nephrotoxicity in pts w/ pre-existing kidney conditions

Levofloxacin: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Avoid excessive sun exposure. Take with plenty of water. Caution in those with renal impairment or a history of seizures.

Labs to Monitor: renal function and electrolytes

Impact on Other Diseases: can increase the risk of tendon rupture, especially in older adults. It can cause QT prolongation, which can be dangerous in pts w/ cardiac conditions

rifampin: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Take on an empty stomach. Avoid alcohol. Caution is advised in pts w/ HIV or those taking other medications that affect liver enzymes

Labs to Monitor: liver function tests

Impact on Other Diseases: may interact with other medications, including antiretrovirals for HIV, and can lower the effectiveness of oral contraceptives

sertraline: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Takes weeks for full effect. Do not stop abruptly. Monitor for suicidal ideation. It may take a few weeks for full effects to be seen. Avoid alcohol.

Labs to Monitor: N/A

Impact on Other Diseases: can worsen conditions like bipolar disorder if not properly monitored. It may also interact with other medications, such as blood thinners, increasing the risk of bleeding

bupropion: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Avoid alcohol. Do not crush or chew extended-release tablets. Monitor for psychiatric side effects, particularly mood changes or seizures. Assess for any signs of suicidal ideation or psychosis.

Labs to Monitor: N/A

Impact on Other Diseases: may lower the seizure threshold and can increase the risk of manic episodes in patients with bipolar disorder

hydroxyzine: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Avoid alcohol and other CNS depressants. Take with food to minimize GI upset. Monitor for sedation, dry mouth, and urinary retention. Assess mental status and level of sedation. Be cautious in older adults and those with a history of respiratory issues. Can worsen glaucoma.

Labs to Monitor: N/A

Impact on Other Diseases: Can worsen glaucoma, urinary retention, and may cause sedation in patients with respiratory conditions.

diazepam: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Avoid alcohol. Monitor for falls in elderly patients. Do not stop abruptly, as this can precipitate withdrawal symptoms. Be cautious when driving or operating machinery.

Labs to Monitor: N/A

Impact on Other Diseases: may exacerbate respiratory depression in patients with COPD or sleep apnea. It can also increase the risk of falls and confusion in elderly patients.

allopurinol: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Encourage hydration to prevent kidney stones. Monitor for rash and liver/kidney function

Labs to Monitor: Uric acid levels, renal and liver function tests

Impact on Other Diseases: can affect renal function, especially in those with pre-existing kidney disease. It should be used cautiously in patients with liver disease. Additionally, it may interact with other drugs like anticoagulants, increasing the risk of bleeding

colchicine: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Take with food to minimize GI upset. Avoid grapefruit juice.

Labs to Monitor: CBC, renal function

Impact on Other Diseases: can cause GI upset and may worsen renal function, especially in pts w/ pre-existing kidney disease

fexofenadine: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Avoid alcohol and CNS depressants. Can be taken with food to decrease GI upset. Avoid grapefruit juice

Labs to Monitor: N/A

Impact on Other Diseases: should be used cautiously in pts w/ kidney disease as the drug is excreted via the kidneys

atenolol: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor BP and HR. Do not stop abruptly (risk of rebound hypertension).

Labs to Monitor: N/A

Impact on Other Diseases: May worsen heart failure in pts w/ poorly controlled heart conditions. Can mask symptoms of hypoglycemia in diabetic pts

timolol: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Do not touch dropper to eye. Hold nasolacrimal duct to prevent systemic absorption.

Labs to Monitor: N/A

Impact on Other Diseases: can exacerbate respiratory conditions such as asthma and can also cause bradycardia and hypotension

amlodipine: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor BP, avoid grapefruit juice,

Labs to Monitor: N/A

Impact on Other Diseases: can lower blood pressure significantly, so caution is required in patients with hypotension or dehydration. It may also exacerbate heart failure and renal impairment in some individuals

nevirapine: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor for liver damage and rashes. Adherence to regimen is crucial.

Labs to Monitor: Liver function tests, CD4 count, viral load

Impact on Other Diseases: can worsen liver disease in patients with pre-existing liver conditions. It may also interact with other medications, such as hormonal contraceptives, reducing their effectiveness

zidovudine: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor for signs of infection or anemia. Adherence to medication regimen is crucial for effectiveness

Labs to Monitor: CBC, liver function tests, lactic acid levels

Impact on Other Diseases: can worsen bone marrow suppression and may increase the risk of infections. It may also interact with other medications, including those that affect liver enzymes

alprazolam: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Avoid alcohol. Do not stop abruptly (risk of withdrawal). Monitor for signs of abuse

Labs to Monitor: N/A

Impact on Other Diseases: Can worsen resp. depression in pts w/ COPD or obstructive sleep apnea. In pts w/ depression, may exacerbate symptoms, especially if used long-term.

montelukast: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: For long-term control, not for acute asthma attacks. Take at bedtime for best results.

Labs to Monitor: N/A

Impact on Other Diseases: generally well-tolerated but can exacerbate psychiatric disorders in vulnerable pts

dexamethasone: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Taper gradually when discontinuing. Monitor blood glucose and infection signs.

Labs to Monitor: Blood glucose, WBC count, electrolytes

Impact on Other Diseases: can exacerbate diabetes, cause fluid retention, and increase the risk of infections. Long-term use can lead to osteoporosis and cataracts.

methylprednisolone: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Do not stop abruptly (risk of adrenal insufficiency). Monitor blood glucose and infection signs. Take with food to prevent GI upset

Labs to Monitor: Blood glucose, WBC count, electrolytes.

Impact on Other Diseases: Long-term use can exacerbate diabetes and osteoporosis. It can also increase the risk of infection due to immune suppression.

hydrocortisone: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Do not stop abruptly. Monitor blood glucose in diabetic patients. Take with food to prevent GI upset

Labs to Monitor: Blood glucose, electrolytes, WBC count

Impact on Other Diseases: Can worsen diabetes and hypertension. It can also suppress the immune system, making infections harder to fight. Prolonged use can lead to osteoporosis and adrenal insufficiency.

ferrous sulfate: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Take on an empty stomach with vitamin C for better absorption; avoid dairy and antacids

Labs to Monitor: Hemoglobin, hematocrit, ferritin, total iron-binding capacity (TIBC)

Impact on Other Diseases: may worsen conditions like hemochromatosis or liver disease

famotidine: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Take with or without food. Avoid alcohol and NSAIDs to prevent irritation. Monitor for signs of GI bleeding

Labs to Monitor: Monitor renal function (serum creatinine) in patients with renal impairment, as the drug is excreted through the kidneys

Impact on Other Diseases: can reduce stomach acid and may affect the absorption of other medications that require an acidic environment for absorption (e.g., certain antifungals, iron)

docusate sodium: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Encourage fluid intake. Do not use long-term. Assess for abdominal distension, bowel sounds, and usual patterns of bowel function.

Labs to Monitor: N/A

Impact on Other Diseases: excessive use may cause electrolyte imbalance, particularly in pts w/ kidney disease or heart conditions

lactulose: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor bowel movements and electrolyte levels

Labs to Monitor: Ammonia levels (in liver disease pts) and monitor electrolyte levels (particularly potassium), as prolonged diarrhea can lead to imbalances

Impact on Other Diseases: Caution in pts w/ DM (d/t high sugar content) and in those with GI obstructions. May exacerbate electrolyte imbalances in pts w/ kidney disease and can cause dehydration if used excessively

filgrastim: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor CBC, especially neutrophil count. Educate about the potential for bone pain. Watch for respiratory symptoms and signs of hypersensitivity

Labs to Monitor: liver function tests, CBC with differential, platelet count, uric acid levels

Impact on Other Diseases: can exacerbate sickle cell disease (triggering crises), may stimulate myeloid malignancies, and can worsen conditions leading to splenic rupture. It may also impact kidney function due to increased uric acid levels.

epoetin: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor BP. Ensure iron intake, monitor hgb levels closely to prevent excessive increases

Labs to Monitor: Hemoglobin, hematocrit, iron studies

Impact on Other Diseases: can exacerbate hypertension and increase the risk of clot formation, which can worsen cardiovascular conditions

acetylcysteine: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Monitor respiratory function, assess for allergic reactions. Instruct the pt that the inhaled form has a strong sulfur smell. Ensure adequate hydration.

Labs to Monitor: Acetaminophen levels (if treating overdose), liver function tests, renal function (BUN, creatinine) if used for nephroprotection

Impact on Other Diseases: Can worsen bronchospasms in asthma. May alter the effectiveness of activated charcoal in poisoning cases.

clopidogrel: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Avoid NSAIDs and aspirin. Report any unusual bleeding.

Labs to Monitor: Platelet count, liver function test, CBC

Impact on Other Diseases: Increases bleeding risk in conditions like peptic ulcer disease, liver disease, and stroke. Can interact with CYP2C19 inhibitors

diphenoxylate/atropine: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Assess for signs of dehydration and electrolyte imbalance. Monitor for CNS effects. Avoid use in infectious diarrhea. : Do not exceed prescribed dose (can cause euphoria). Avoid alcohol and CNS depressants

Labs to Monitor: liver function test and electrolytes

Impact on Other Diseases: Can worsen toxic megacolon in infectious diarrhea. May cause severe constipation in opioid-naïve patients.

infliximab: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Screen for TB before starting treatment. Monitor for signs of infection.

Labs to Monitor: CBC, liver function tests, TB screening

Impact on Other Diseases: Can increase infection risk in immunocompromised pts, reactivate latent TB or hepatitis B, and worsen heart failure

alendronate: nsg considerations & pt ed, labs, impact on other diseases

Nsg Considerations & Pt Education: Take with a full glass of water in the morning before food; remain upright for at least 30 minutes after taking. Monitor bone density

Labs to Monitor: Calcium & Vit D

Impact on Other Diseases: can worsen GERD and dysphagia, can also exacerbate hypocalcemia, Long-term use has been associated with atypical femur fractures