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Is Pain one of main reason why people seek health care?
Yes
Is pain objective or subjective?
Subjective
What type of conditions would a paitent have to not be able to report pain?
Comatose
Dementia
Mentally Disabled
Aphasia
What are some biases that a healthcare provider can have that might cloud judgemtn of pain?
Different Culture
Personal Bias, way of viewing the paitent, like thinking if they are drug seeking
Lack of education of pain managemtn
What do Margo Mccaffery say for pain?
Whatever the person experiencing the pain says it is, existing whenever the person says it does.
What does the International Association for the study of Pain (IASP) say about pain?
An unpleasnt sensory and emotional experience assoicated with actual or potential tissue damanage or described in terms of such damange
What are 10 principles and Practice Stands for pain treatment
Continous assessment for pain
Hollistic approach
Pain managemnt for all
Use pain amnagemtn for acitivites that are supposed to help them
Use all drug types for more effective and least invasive
Collab with all healthcare team members
What is Nocicpetive Pain
Bodys normal healthy functionng response to tissue pain
What is the order of the 4 process that need to happen for nociception to happen
1) Transduction
2) Transmission
3) Perception
4) Modulation
What happens in the Transduction step of Nociception
1) Injured cell site releases mixture of chemicals to nerve endings (Nociceptors), which creates an action potential
Chemicals: Prostaglandins, Bradykinin, Serotonin Histamine

What happens in the Transmission step of Nociception
Action potential travels to nerve fibers and ending up in spinal cord to the cortex in brain for processing

What happens in the Perception step of Nociception
Pain is made concious

What happens in the modulation step of Nociception?
Substances are released back to periopherals in order to manage pain and modify incoming impulses

Whats the difference between Somatic and Visceral Tissue?
Somatic Tissue: Structures you can see and touch externally
Visceral tissue: Internal Organs and internal lining
What does Somatic: Superficial and Deep mean
Superficial: Skin, Mucous membrnes, subcutaneous tissue
Deep: Bone, JOin, Muscle,
What is Somatic: Superficial pain described as
Sharp, Burning Prickly
What is Somatic: Deep pain described as?
Aching or Throbbing
Where are teh nociceptors for Visceral pain
Interal Organs
Lining of body cavities
What is Visceral pain usally caused by
Inflammation, Strestching, Ischemia,
Stretching caused by tumor or obstruction
What is Neuropathic Pain
Pain caused by actual damage to nerves of the PNS or CNA
What does Neuropathic pain feel like?
Numbing, Hot, Burning, Shotting, Stabbing, Electric Shock Like
Sudden, Intense, Short Lived, Lingering
What are the causes of Neuropathic pain?
Diabetes, Trauma, Inflammation, Metabolic Diseases
What type of analgesic is used to treat neuropathy?
Adjuvant analgesics
Medications that arent primarily used to treat pain
Multimodal approach
When assessing a patient for pain subjectivley what Acromym shoudl be used
OPQRST
Onset
Precipitating Factors
Quality
Radiation
Severity
Timing
What assessing pain objectively for patient what tool should be used?
Behavior Pain Scale: For sedated adults

What are the ways to measure intensity of pain ?
Pain Scale: 0-10
Verbal Descriptor Scale
Visual Pain Scales for nonverbal paitents
What are the defining Quality of Neuropathic Pain
Stabbing
Quiick
Burning
Electric
Itchy
Numbing
Shooting
What are the defining qualities of Nociceptive Pain
Sharp
Aching
Throbbing
Dull
Cramping
Why is it important to reassess for Pain
Changes in
Severity
Physical and psychosical condition
Intervention can change pain
Adverse effecvts from treamnts
Agency policy
Whats the differnce betwen Acute and Chronic Pain
Acute: Activates flight or fight.
Chronic: Baseline Vitals, body adapts
However behavior changes: Immobility Withdrawl Despair
What are examples of nondrug treatments
Hot and COld pads
Relaxation
Music, Massage
DIrection
What are examples of Drug Therapy?
Non Opiods
Opiods
Adjuvant
For a paitent with a functing GI system is Oral Admin route prefered?
Yes
Why do oral doses have to be larger compared to other routes of medication
First pass effect because it goes through the GI system
Liver metabolizes most of it
What is a paitent controlled analgesia (PCA)
IV pump controlled by paitent
IV Opoid
Can paitentes overdose on a PCA pump
NO
After giving IV pain medication how long shoudl the nurse wait to reasses for pain
15-30 minutes
After giving Oral pain medication how long should the nurse wait to reassesss for pain
30-60
What are some examples of nonopioids?
Acetaminophone
Aspirin
NSAIDs
Can you be be physically depedable on nonopoids
NO
Can you build a tolerance to nonopoids?
no
What is the opoid sparning effect?
Non opoids are combined with opoids in order to lower the dose of opoids given to smoeone
IS there a dosage ceiling to nonopoids
yes there is a max ceiling meaning they are only so powerful
Opoids have no ceiling
Does Aspirin reduce inflammation
Yes
What are the organs at risk when taking aspirin
GI
Kidney
Hypertension
What does aspirin do for platelet aggregation (clotting)
Decreases clotting
Compared to Aspirin, Acetaminophin doesn’t have
Antiplatelet or antiinflammatory effects
What is the organ at risk when taking aceteamenophin?
Liver-Hepatotoxicity
Are NSAIDS, opoids or nonopioids? What does it stand for
NONOPIOIDS
Non Sterioidal Anti Inflammitory drugs
What do NSAIDs inhibit?
cyclooxygenase (COX)
-Stops Prostaglanis formation
Is Aspirin a NSAIDs
Yes
What is the difference in how Opiods work and Nonopioids
Opioids Bind to Opioid Receptors in CNS
Nonopioids block prostaglandis from forming
Is it true Opoids bind to receptors in the CNS to block the pathway for Nociceptive Pain
Yes
Do Opiods alter limbic system activity
Yes
This allows for decreased emotional response to pain
What are mu receptors
Receptors on Nerves that wen activated, provide strong pain relief
What are Pure Agonists?
Drugs that when attatched to someone turn it one 100%
What are examples are pure agonist that bind to mu receptors
Morphone
Oxycodone
Codeine
Do opiods have a analgesic ceiling
no
They will be more powerful as you dose up
What is the biggest danger with opioids?
Respiratory depression
What is special about the opioid Methadone
Mu Agonist
NMDA receptor anatgonist - stops nerve over activation
What is the opioid Methadone used for
Chronic Pain
Neuropathy
What are the Common side effects of opioids
Constipation
Nausea/vomiting
Sedation
Repiratory depression
Itching
What drug reverses the effects of opioid overdose
Narcan
Can people on opoids build dependence
Yes
In opioid naive paitents are they at a high or low risk of opioid induced repiratory depression
High risk
In opioid tolerant paitents are they at a high or low risk of opioid induced repiratory depression
Low risk
What is the main complaint about epidural and intrathecal routes of opioid admin
Itching
For a standard paitent what type of medication plan would you see, and frequency?
PRN Acetaminophine, PRN NSAIDS, PRN opioids
For a paitent post operation what medication plan would you see
Schduled Acetaminophone and SAIDS and PRN opiods
When given a dose range like 5-10 mg how much should you admin for the first time
5 mg
Why should you not use IV meds to pre medicate for anticipated pain
Because they act fast and wear off rapidy
How is titration level determined
Based on assessment of analgesic effect and side effects
What is Equianalgesic Dosing
Making one dose of a medication equivilant to another medication
When would you do Equianalgesic dosing
When switching medication from IV to PO
When discharing a patient home
Changing of medication
According to the WHO step ladder what are the 3 steps catagorized for
Step 1: Mild Pain
Step 2: Moderate Pain
Step 3: Severe pain
What is Pseudo Addiction
Apperance of drug seeking behavior from paitents who don’t have adequate pain managemnt
What are examples of interventional ( tiny tools) therapy?
Nerve Blocks
Neuroablative Techniques (Permanently destroying painful nerve pathway)
What are some physical nondrug therapies
Physical
TENS
Exercise
Hot or Cold Therapy
Massage
Acupuncture
What are some cognitive therapies for nondrug pain managment
Cognitive Therapy
Distrction
Relaxation
Teaching
What are the benefits of nondrug therapy for pain
Reduces the actual drug doses, reducing side effects
Increase personal control
Why is tolerance a barrier to effective pain management?
Because it increases the dose needed for analgesic effects causing worse side effects
causes Opioid Rotation
Opioid induced hyperalgesia
Why is physical dependence a barrier to effective pain management
Body adapts to opioids and therefore you need more
Withdrawl happens
What is the def of addiction
Neurobiologic cindition with a a drive to obtain and take substances for other than prescribed therapeutic value
Are tolerance and physical depdendce signs of an addiction
No
What are characteristics of addiction
Compulsive use
Loss of control when using
Continued used despite harmful effect
What are the effects of untreated pain to the endocrine system
Stress hormones released
What are the effects of untreated pain to the Cardiovascular/Respiratory system
Pain increases Sympathetic system
Causes increase output and overworking it
What are the effects of untreated pain to the GI system
Cahnges in appetitie
Causing decrease motility
Anorexia
Low energy
What are the effects of untreated pain to the to the Urinary system
Causes urine retention due to increase substances i body that retain urine
What are the effects of untreated pain to the muscular system
Muscule tention due to constant pain
Muscle antrophy
Contractures
What are the effects of untreated pain to the Neuro system
Complex Regional Pain Sydrome (CRPS)
Constant pain
When Geriatric paitents take pain meds what are items to remember
Slower metabolism of drugs
GI blooding
Polypharmacy
Cognitive Impairment