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HIV initiates replication by latching on to which two proteins?
CD4 and CCR32 (a coreceptor)
Delta32 and CCR5
CD4 and CCR5 ( a coreceptor)
TCR and CD4
CD4 and CCR5 ( a coreceptor)
HIV follows which flow of genetic information?
DNA to RNA to mRNA to protein
RNA to DNA to mRNA to protein
RNA to mRNA to DNA to protein
Protein to DNA to mRNA
RNA to DNA to mRNA to protein
Mutation rates can be influenced by:
The environment
The gene region
The species
All of the above
All of the above
The fungus Phytopthera infestans caused the Irish potato famine because it infected potato crops and made them rot. Phytopthera infestans is only virulent when it can avoid the potato plant’s defenses.
A loss-of-function mutation in the Avirulence gene allows this to happen and causes potato disease, but only when fungal strains are homozygous recessive (aa), not when they are AA or Aa. You observe potato crop where 75/100 plants have rotted from Phytopthera infes at the Avirulence locus, what is the frequency of the a allele?
Not enough information
100%
50%
75%
Not enough information
The delta-32 allele has the lowest frequencies in areas where
HIV infection is rampant or abundant
HIV infection is rare
HIV strains are missing the viral protein Nef
HIV contains the CD4 receptor within its RNA genome
HIV infection is rampant or abndant
How does AZT work?
Is a HAART cocktail
Helps reverse transcriptase add more thymidine to the proteins
interrupts the pathway that adds more nucleotides
AZT is not a drug
Interrupts the pathway that adds more nucleotides
The amount of sunlight any orchid receives per day influences growth rates, flowering time, and number of flowers. This is an example of:
Phenotypic influence
Phenotypic cognition
Phenotypic plasticity
Phenotypic diversity
Phenotypic plasticity
What is a paraphyletic group of organisms?
Groups that include paranormal species and their ancestors
Group that includes a common ancestor and some but not all descendants
Groups that include all descendants of a common ancestor
Groups that include all but one descendent of a common ancestor
Group that includes a common ancestor and some but not all descendants
Which of the following may explain why HIV-1 is highly lethal?
Because evolution is short sighted
Because HIV infects host immune cells
Because the high mutations rate of RNA viruses allows natural selection
Because HIV viral loads increased over time
All choices are correct
All choices are correct
Evolution is progressive in that complexity is always increasing with time
True
False
False
What is it called when two species experience similar environments and evolve the same adaptations?
Coincidence
Coevolution
Convergence
Co-adaptation
Convergence
In Sub-sharan Africa, the primary mode of transmitting HIV is?
Transfusions with contaminated blood
Consuming bush meat
Male-Male sex
Male-female sex
Male-female sex
Bayesian phylogentic analysis differs from Maximum Likelihood methods in that:
They are based on the principle of parsimony
They use a bootstrapping process to determine confidence in the results
They infer the likelihood of the data given a tree
They infer the likelihood of a tree given the data
They infer the likelihood of a tree given the data
Because finches with large beaks gave birth to chicks with bigger beaks?
Beak size is a heritable trait
This example gives evidence for the inheritance of acquired characteristics
Beaks size does not influence survival
Conspecific nest parasitism probably doesn’t occur
Beak size is a heritable trait
Which of the following can cause AZT to become less effective as a treatment for HIV infection?
Virions inside a person can mutate to a form that does not allow reverse transcriptase to incorporate AZT into DNA strands
All choice are correct
Virions inside a person can mutate to a form that allows reverse transcriptase to use AZT as an efficient DNA building block
AZT molecules eventually mutate into regular thymidine
Virions inside a person can mutate to a form that does not allow reverse transcriptase to incorporate AZT into DNA strands
Which of the following doe not provide evidence for evolution?
The human hemoglobin family
Theory of Plate Tectonics
Discovery of Archaeopteryx
The immutability of species
The immutability of species
Shared similarity of genetic flaws (e.g. mutations)
Provides further evidence of common descent
Cannot yet be explained by evolutionary biologists, but will likely be explained some day
Helps identify disease
Does not occur
Provides further evidence of common descent
The age of processed pseudogenes can be estimated by the number of mutations they have accumulated. We expect to find that
Older pseudogenes are shared by few species
Older pseudogenes are shared by more species
The older the pseudogene, the less valuable it is for determining relationships
Newer pseudogenes are shared by many species
Older pseudogenes are shared by more species
How does a biologist assess confidence in a particular node of a phylogentic tree?
Maximum likelihood
Polytomy
Bootstrapping or posterior probabilities
Bayesian Markov Chain Monte Carlo
Bootstrapping or posterior probabilities
What is a synapomorphy?
A unique trait found in a species
A common trait found with no shared ancestry
A homologous trait that is shared among certain species
A trait that is shared with the out group
A homologous trait that is shared among certain species
If a phylogenetic tree depicts extant taxa on the right and the point of most recent common ancestry on the left:
An accurate phylogeny only shows taxa on the top and the most recent common ancestor on the bottom
The horizontal axis represents time
The vertical axis represents time
The amount of time since the most recent common ancestor depends on the vertical spacing between taxa
The horizontal axis represents time
HIV was introduced into humans only once (from SIV)
False
True
False
Polyploidy in animals is rare because:
They frequently have temperature-dependent sex determination
Recombination between parents ensure diploidy in offsprings
They are not as promiscuous as plant or fungi
Diploid gametes most often combine with haploids, producing an unstable triploid
Diploid gametes most often combine with haploids, producing an unstable triploid
DNA and protein studies reveal that:
Variation among individuals and populations is ubiquitous
Variation is widespsread among populations but not species
Variation is lower than what was previously thought
Variation is widespread among species but not populations
Variation among individuals and populations is ubiquitous
In the chronic phase of HIV infection, CD$ T-cell counts decrease continually?
False
True
True
In a phylogeny, when evolutionary histories are not well resolved and the node has multiple (more than two) branches arising from it this is known as:
Polytomy
Triploidy
Monophyletic groups
Autapomorphies
Polytomy
Historically, snakes had legs and now they are vestigial structures in certain species
False
True
True
Which type of HIV virus is causing the AIDS epidemic?
HIV-2 subtype A
SIVstm: stump-tailed macaque
HIV-1
HIV-2 subtype B
HIV-1
Evolution cannot anticipate the future and produces changed in populations based on past environments, not future environments
False
True
True
During a drought in the Galapagos, small, easily eaten seeds become less abundant leaving only large, hard-cased seed only birds with large beaks can eat. If this drought persist for several years, then what would be expected from natural selection
Small birds growing larger beaks by exercising their mouth parts
More birds with small beaks dying than large-beaked birds gicing way to offspring produced in subsequent generations having a higher percentage of large-beaked birds
Birds with larger beaks eating less to save some for birds with smaller beaks
Birds with small beaks mutating their beak genes with the result that later-generation offspring have larger beaks
More birds with small beaks dying than large-beaked birds gicing way to offspring produced in subsequent generations having a higher percentage of large-beaked birds
A cladogram is a tree based on:
Clustering only morphological traits
Clustering only genetic similarities
Clustering only synapomorphies
Clustering all traits with non-negligible branch lengths
Clustering only synapomorphies
Isotopes with shorter half-lives are more useful for dating the age of Earth:
False
True
False
Viral load in a patient that is HIV positive?
Continues to decrease until the patient develop AIDS
Initially increases, then decreases, and then increases until the patient develop AIDS
Initially decrease, then increases until the patient develops AIDS
Continues to increase until the patient develop AIDS
Initially increases, then decreases, and then increases until the patient develop AIDS
A reaction norm is:
The average time it takes to answer this or any other question
The genotypic expression range in a single environment
The phenotypic possibilities of a single genotype across an environmental range
The opposite of phenotypic plasticity
The phenotypic possibilities of a single genotype across an environmental range
The unit(s) upon which evolution consist of happens to be
Changes in genotypes
Changes in allele frequencies
Changes in phenotypes
Changes of heritability
Changes in allele frequencies
Which is NOT a category of drugs in use to disrupt which stage of HIV’s life cycle?
Fusion inhibitors
Cholesterol Inhibitors
Integrase Inhibitors
Coreceptor inhibitors
Cholesterol inhibitors
During years 1-6 of infection, HIV evolution is extremely fast, but it slows down during year 7. What would be the underlying cause for the HIV virus evolution to slow?
Viral load decrease
Replication of the HIV virus decreased
Increase in the change of novel epitopes
CD4 T cell count decrease
CD4 T cell count decrease
When Darwin first proposed evolution:
No theory could explain that the earth was old enough for natural selection to work
Geologists had already observed that vast stretched of time were required to produce some rock formations
Some geologists believe that earth was unchangeable ( uniformitarianism)
catastrophism was already accepted among geologists to explain that the earth was older than commonly believed
Geologists had already observed that vast stretched of time were required to produce some rock formations
During the Chronic phase of HIV infection, the patient usually experiences few symptoms
False
True
True
The Modern Synthesis is grounded in which of the following discipline synthesized with the theory of evolution:
Genetics
Thermodynamics
Geology
Mathematic
Genetics