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As the frequency of semen collection or sexual activity is increased:
a. the rate of passage through the caput, corpus epididymis is unaffected and the rate of passage through the cauda is increased
b. the rate of passage through the caput and corpus epididymis is increased and the rate of passage through the cauda is unaffected
c. the rate of passage through the caput epididymis is increased and the rate of passage through the corpus and cauda epididymis is unaffected
d. the rate of passage through the caput, corpus, and cauda epididymis is unaffected
e. the rate of passage through the caput, corpus, and cauda epididymis is increased
a. the rate of passage through the caput, corpus epididymis is unaffected and the rate of passage through the cauda is increased
In Freemartinism:
a. The complete separation of the two placentas causes abnormal female tract development
b. AMH from the male causes abnormal female tract development
c. the complete separation of the two placentas causes abnormal development of both twins
d. AMH from the female causes abnormal male tract development
b. AMH from the male causes abnormal female tract development
Phenotypic sex can be different than gonadal sex when:
a. the individual has XXY sex chromosomes
b. the gene encoding the androgen receptor has an inactivating mutation
c. the Sry gene is mutated
d. the Sox9 gene is mutated
b. the gene encoding the androgen receptor has an inactivating mutation
Usually, males that are bilateral cryptorchids are:
a. feminized but fertile
b. completely lacking testes
c. have one undescended testis that does not produce sperm
d. infertile but masculine-appearing
d. infertile but masculine-appearing
The reason that a cell-permeable activator of guanylate cyclase would not be a drug of choice for erectile dysfunction is that:
a. it would block an erection
b. It would break down GTP
c. it would have many side effects because of the multiple functions of guanylate cyclase in different cells and tissues
d. it would break down GMP
e. it would break down cGMP
c. it would have many side effects because of the multiple functions of guanylate cyclase in different cells and tissues
If your grandfather confides in you that he has an elevated PSA and asks what that means, to be accurate, you should tell him that:
a. he has prostate cancer
b. he has a 25-30% likelihood of not having prostate cancer
c. he has a 25-30% likelihood of having prostate cancer
d. he has a 70-75% likelihood of having prostate cancer
e. he has a 70-75% likelihood of having benign prostatic hyperplasia
c. he has a 25-30% likelihood of having prostate cancer
Gonads from XY individuals instruct the invading primordial germ cells to:
a. complete mitosis, enter meiosis, and arrest in meiosis
b. complete meiosis, enter mitosis, and arrest in mitosis
c. arrest in mitosis before entering meiosis
d. immediately develop into mature sperm
c. arrest in mitosis before entering meiosis
The pampiniform plexus surrounds the testicular artery to:
a. cool the blood in the network of veins in the plexus
b. increase the surface area to allow for efficient waste removal.
c. increase the surface area to allow for heat exchange
d. cool the blood that enters the body
e. increase the surface area to allow for more efficient blood exchange
c. increase the surface area to allow for heat exchange
The observation that animals that express the Sry gene but have mutations in the Sox9 gene do not form testes should tell you that:
a. Sry requires Sox9 for testis formation
b. Sox9 protein turns on the SRY gene for testis formation
c. Sox9 requires Sry for testis formation
a. sry requires Sox9 for testis formation
In XX individuals, the paramesonephric ducts will partially fuse together to form
a. the epididymis
b. the oviducts, uterus, cervix and part of the vagina
c. the ovaries
d. the vestibule
b. the oviducts, uterus, cervix and part of the vagina
The cells that produce testosterone are located:
a. in the adluminal compartment
b. in the interstitial compartment
c. in the basal compartment
d. inside the seminiferous tubules
b. in the interstitial compartment
The 3 phases of spermatogenesis are, in chronological order:
a. meiosis, mitosis, differentiation
b. spermatocytogenesis, meiosis, spermiogenesis
c. differentiation, meiosis, stem cell mitosis
d. spermiogenesis, meiosis, spermatocytogenesis
e. differentiation, meiosis, proliferation
b. spermatocytogenesis, meiosis, spermiogenesis
Dihydrotestosterone carries out most of its actions on target tissues by:
a. diffusing across the plasma membrane, binding to a receptor in the nucleus, activating a G protein, adenylate cyclase,and increasing cAMP and protein phosphorylation
d. diffusing across the plasma membrane, binding to a receptor in the nucleus of cells that, in turn, regulates gene transcription
c. binding to a receptor on the target cell plasma membrane that is a transcription factor
d. diffusing across the plasma membrane, activating a G protein, adenylate cyclase, and increasing cAMP and protein phosphorylation
e. diffusing across the plasma membrane, binding to a receptor in the cell cytosol that activates a G protein and then adenylate cyclase to increase the production of cAMP, activate protein kinase A and affect protein phosphorylation.
d. diffusing across the plasma membrane, binding to a receptor in the nucleus of cells that, in turn, regulates gene transcription
Genetic recombination during spermatogenesis begins when males:
a. are in the early fetal stage
b. are in the late fetal stage
c. enter puberty
d. are born
c. enter puberty
The sperm tail is moved by _________________ with dynein feet that use ___________ to slide across each other.
a. mitochondria, ATP
b. microfilaments, GTP
c. microtubules, ATP
d. microfilaments, ATP
e. microtubules, GTP
c. microtubules, ATP
These unusual structures found on male germ cells help to synchronize the timing and development of the germ cells:
a. cytoplasmic bridges that allow RNA and other molecules to pass from one cell to another
b. gap junctions that allow RN and other molecules to pass through
c. structures that allow secreted hormones to move from one cell to another
d. structures that allow secreted growth factors to move from one cell to another
e. bridges that are functional only between spermatogonia
a. cytoplasmic bridges that allow RNA and other molecules to pass from one cell to another
A former baseball player took human chorionic gonadotropin (hCG), which acts very much like LH, to enhance his performance. What would you expect the outcome to be?
a. no change in his endogenous testosterone production
b. decreased endogenous testosterone production
c. increased endogenous testosterone production
d. he might become pregnant
e. he would paradoxically become more feminine in appearance due to negative feedback
c. increased endogenous testosterone production
The anterior pituitary is pivotal in controlling testosterone production because it:
a. produces FSH that acts on Leydig cells
b. produces LH that acts on Leydig cells
c. produces FSH that acts on Sertoli cells
d. produces GnRH that acts on Sertoli cells
b. produces LH that acts on Leydig cells
Sertoli cells are:
a. cells outside the seminiferous tubule that help germ cells develop to sperm
b. cells inside the seminiferous tubule that help germ cells develop to sperm
c. somatic cells outside the seminiferous tubule that migrate into the tubule to help germ cells develop into sperm
d. somatic cells that differentiate into mature sperm
b. cells inside the seminiferous tubule that help germ cells develop to sperm
Cells that are protected by the blood-testis barrier are:
a. spermatogonia
b. leydig cells
c. sertoli cells
d. pre-meiotic and meiotic male germ cells
e. spermatocytes and spermatids
e. spermatocytes and spermatids