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Name the 5
IgG, IgM, IgA, IgD, & IgE
IgG
Monomer -In blood, lymph, & intestine
80% of serum antibodies - Cross placenta
Fix complement
- enhance phagocytosis; neutralize toxic & viruses; protect fetus & new born
IgM antibodies
Prentamer -6% of serum antibodies
Fix complement - Remain in blood vessels
Agglutinate microbes; first Ab produced in response to infection
IgA Antibodies
Dimer -13% of serum antibodies
In secretions - mucosal protects
*secretions like mucous membranes, saliva, tears, & breast milk
IgD Antibodies
Monomer - 0.02% of serum antibodies
In blood, in lymph, & on B cells
No well defined function; assists in the immune response on B cells
IgE Antibodies
Monomer -0.0002% of serum antibodies
On mast cells & basophiles, in blood
Allergic reaction; lysis of parasitic worms