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Acetylcholine (ACh)
Type: excitatory/inhibitory
Function: muscle, learning, memory
Malfunction: too little = Alzheimer’s
Dopamine
Type: excitatory/inhibitory
Function: movement, learning, attention, emotion
Malfunction: too much = schizophrenia
too little = Parkinsons’s
Serotonin
Type: inhibitory
Function: mood, hunger, sleep, arousal
Malfunction: too little = depression
Norepinephrine
Type: excitatory
Function: alertness, arousal
Malfunction: too little = depresses mood
GABA (gamma-aminobutyric acid)!
Type: main inhibitory in CNS
Function: regulates anxiety, stress, sleep
Malfunction: too little = seizures, tremors, insomnia
Glutamate!
Type: main excitatory
Function: learning, memory, cognition, plasticity
Malfunction: too much = brain overstimulation to migraines, seizures
Endorphins
Type: inhibitory
Function: perception of pain and pleasure
Malfunction: too much from opioid use = suppression of natural supply
Substance P
Type: excitatory
Function: pain perception and immune response
Malfunction: too much = chronic pain