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anaphase
stage of mitosis during which sister chromatids are separated from each other
binary fission
prokaryotic cell division process
cell cycle
ordered series of events involving cell growth and cell division that produces two new daughter cells
cell cycle checkpoint
mechanism that monitors the preparedness of a eukaryotic cell to advance through the various cell-cycle stages
centriole
rod-like structure constructed of microtubules at the center of each animal cell centrosome
centromere
region at which sister chromatids are bound together; a constricted area in condensed chromosomes
chromatid
single DNA molecule of two strands of duplicated DNA and associated proteins held together at the centromere
cleavage furrow
constriction formed by an actin ring during cytokinesis in animal cells that leads to cytoplasmic division
cytokinesis
division of the cytoplasm following mitosis that forms two daughter cells.
diploid
cell, nucleus, or organism containing two sets of chromosomes (2n)
G0 phase
distinct from the G1 phase of interphase; a cell in G0 is not preparing to divide
G1 phase
first phase of interphase centered on cell growth during mitosis
G2 phase
third phase of interphase during which the cell undergoes final preparations for mitosis
gamete
haploid reproductive cell or sex cell (sperm, pollen grain, or egg)
Gene
physical and functional unit of heredity, a sequence of DNA that codes for a protein.
haploid
cell, nucleus, or organism containing one set of chromosomes (n)
homologous chromosomes
chromosomes of the same morphology with genes in the same location; diploid organisms have pairs of homologous chromosomes (homologs), with each homolog derived from a different parent
interphase
period of the cell cycle leading up to mitosis; includes G1, S, and G2 phases (the interim period between two consecutive cell divisions)
locus
position of a gene on a chromosome
metaphase
stage of mitosis during which chromosomes are aligned at the metaphase plate
metaphase plate
equatorial plane midway between the two poles of a cell where the chromosomes align during metaphase
mitosis
(also, karyokinesis) period of the cell cycle during which the duplicated chromosomes are separated into identical nuclei; includes prophase, prometaphase, metaphase, anaphase, and telophase
spindle
apparatus composed of microtubules that orchestrates the movement of chromosomes during mitosis
oncogene
mutated version of a normal gene involved in the positive regulation of the cell cycle
prometaphase
stage of mitosis during which the nuclear membrane breaks down and mitotic spindle fibers attach to kinetochores
prophase
stage of mitosis during which chromosomes condense and the mitotic spindle begins to form
proto-oncogene
normal gene that when mutated becomes an oncogene
s phase
second, or synthesis, stage of interphase during which DNA replication occurs
telophase
stage of mitosis during which chromosomes arrive at opposite poles, decondense, and are surrounded by a new nuclear envelope