22. Interstitial (reactive blood) cells. Types, histogenesis, structural, ultrastructural and functional characteristics

Interstitial (reactive blood) cells are primarily involved in __________.

immune response and tissue repair.

The key types of interstitial (reactive blood) cells include __________ and __________.

macrophages and fibroblasts.

Histogenesis of interstitial (reactive blood) cells occurs during __________.

tissue injury and inflammation.

The structural characteristic of interstitial (reactive blood) cells includes __________.

irregular shapes and ability to migrate.

Functionally, interstitial (reactive blood) cells play a role in __________.

wound healing and combating infections.

Ultrastructural features of interstitial (reactive blood) cells are visible with __________ microscopy.

electron microscopy.

The primary role of macrophages as interstitial cells is to __________.

phagocytose pathogens and debris.

Fibroblasts are crucial for __________ in connective tissue.

producing extracellular matrix.

what is the blood plasma that escapes called/

interstitial or extracellular

extracellular fluid

• fluid that is not contained in cells for example found in : blood, lymph, body cavities lined with serous membrane, channels of the brain, spinal cord, other body tissues

• tend to have a constant environment for cellular operations high Na+ low K+

• can be divided into interstitial fluid and blood plasma

• it has transcellular fluid making up 2.5%

• normal glucose concentration is 5mm

• pH is tightly regulated at around 7.4

• 15L volume typically

• contains extracellular matrices that act as fluids of suspension for cells and molecules in the ECF

intracellular fluid

unlike extracellular fluid with a contant environment they tend to have low Na+ and high K+