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Endocrine Disruptors
chemicals that interfere w/hormonal systems
bind to cellular receptors meant for hormones blocking the hormone from being received or amplifies its effects
Common Source of Endocrine Disruptors
human medications passed through urine & into sewage or flushed down toilet
Endocrine Disruptor- Atrazine
herbicide to control weeds & prevent crop loss
Atrazine Effect Example
binds to receptors of cells in frogs that should convert in male frogs leading to high estrogen in males, low sperm count, & feminization (development of eggs in testes or ovary formation)
Endocrine Disruptor- DDT
insecticide
Endocrine Disruptor- Phthalates
compounds in plastic & cosmetics
Endocrine Disruptor- Lead, arsenic, mercury
heavy metals
Endocrine Disruptor- Mercury
natural in coal (not toxic on its own)
released by: coal combustion, trash incineration, burned medical waste, heating limestone for cement
Methylmercury
mercury that has become toxic in water-> neurotoxicant
Teratogen
chemical harmful to developing fetuses accumulate in fetus brain
Mercury Effect Example
inhibits estrogen & insulin (interferes w/ menstrual cycle & ovulation)
Arsenic
natural element in rock underground that dissolves in drinking water and is worsened by mining
*can be removed w/water filters
Carcinogenic
can cause cancer
Lead
found in paint in old homes, water pipes, and soils contaminated by PM from vehicle exhaust; also released in fly ash of coal combustion
*can be removed w/water filters
Neurotoxicant
damages CNS
Coal Ash
source of mercury, lead, arsenic