PRRs versus antigen receptors

What promotes interferon production?

Viral sensors

What are invariant ligands?

A broad range of pathogens are detected with a limited set of receptors

What are shared receptors?

The same ligands drive diverse responses

What makes the Ig domain very stable?

Intramolecular disulfide bonds

What mediates antigen binding?

Variable domains

What provides structure in a receptor?

The constant domain

How does the secreted form of a BCR differ from the membrane bound form?

It has a hydrophilic segment at the c-terminus

Which antibody isotypes do not have a hinge region?

IgE and IgMW