PRRs versus antigen receptors
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What promotes interferon production?
Viral sensors
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What are invariant ligands?
A broad range of pathogens are detected with a limited set of receptors
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What are shared receptors?
The same ligands drive diverse responses
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What makes the Ig domain very stable?
Intramolecular disulfide bonds
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What mediates antigen binding?
Variable domains
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What provides structure in a receptor?
The constant domain
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How does the secreted form of a BCR differ from the membrane bound form?
It has a hydrophilic segment at the c-terminus
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Which antibody isotypes do not have a hinge region?
IgE and IgMW
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