IPS1 - [Sterile Dosage Forms] - Implants, Vaginal Inserts

Proverbs 16:3

Implants

These are long-acting dosage forms that provide continuous release of the drug, often for periods of months to years.

TRUE

TRUE OR FALSE:

Implants can be administered for SYSTEMIC or LOCAL delivery.

Leuprolide acetate implant (Viadur)

Example of implants

Vaginal Inserts

These are OVOID or PEAR-shaped compressed tablets inserted into the vagina using a plastic inserter.

TRUE

TRUE OR FALSE:

Vaginal inserts can be used for SYSTEMIC or LOCAL therapy.

● Filler: lactose

● Disintegrating agent: starch

● Dispensing agent: PVP (polyvinylpyrrolidone)

● Lubricant: magnesium stearate

Common formulation of vaginal inserts:

Lactose

Filler used in vaginal inserts

Starch

Disintegrating agent used in vaginal inserts

PVP (polyvinylpyrrolidone)

Dispensing agent used in vaginal inserts

Magnesium stearate

Lubricant used in vaginal inserts

● Vagifem (estradiol)

● Nystatin vaginal tablets

Examples of vaginal inserts