Small size, in general, is necessary for all cells, whether prokaryotic or eukaryotic. As a cell increases in size, its surface area-to-volume ratio decreases. If the cell grows too large, the plasma membrane will not have sufficient surface area to support the rate of diffusion required for the increased volume. In other words, as a cell grows large in size, it becomes less efficient in performing cellular processes! Other ways are to increase surface area is by folding of the cell membrane, become flat or thin and elongated, or develop organelles that perform specific tasks. These adaptations lead to developing more sophisticated cells, which we call eukaryotic cells.